GRM8 Products
(Glutamate Receptor, Metabotropic 8 (GRM8))
Categories
L-glutamate is the major excitatory neurotransmitter in the central nervous system and activates both ionotropic and metabotropic glutamate receptors. Glutamatergic neurotransmission is involved in most aspects of normal brain function and can be perturbed in many neuropathologic conditions. The metabotropic glutamate receptors are a family of G protein-coupled receptors, that have been divided into 3 groups on the basis of sequence homology, putative signal transduction mechanisms, and pharmacologic properties. Group I includes GRM1 and GRM5 and these receptors have been shown to activate phospholipase C. Group II includes GRM2 and GRM3 while Group III includes GRM4, GRM6, GRM7 and GRM8. Group II and III receptors are linked to the inhibition of the cyclic AMP cascade but differ in their agonist selectivities. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Jul 2008].
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Featured GRM8 Categories
GRM8 Antibodies
High quality antibodies with extensive validation data.
GRM8 ELISA Kits
Reliable ELISA kits for a wide range of species.
GRM8 Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended GRM8 Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB, ELISA, FACS
Validations
- (5)
Cat. No.
ABIN5611162
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, IHC, ELISA
Validations
- (3)
Cat. No.
ABIN7181343
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Bat, Chicken, Dog, Hamster, Horse, Human, Monkey, Mouse, Rabbit, Rat, Sheep
Application
IHC, IHC (p), ICC
Validations
- (3)
Cat. No.
ABIN1048944
Quantity
50 μg
Datasheet
Datasheet
Recommended GRM8 ELISA Kits
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human, Mouse, Rat
Analytical Method
Qualitative Cell ELISA
Validations
Cat. No.
ABIN1381317
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Human
Analytical Method
Quantitative Competition ELISA
Validations
Cat. No.
ABIN1743306
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Sheep
Analytical Method
Validations
Cat. No.
ABIN1774211
Quantity
96 tests
Datasheet
Datasheet
Recommended GRM8 Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1355789
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
Cat. No.
ABIN1330189
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Mammalian Cells
Validations
Cat. No.
ABIN7538306
Quantity
50 μg
Datasheet
Datasheet
Latest Publications for our GRM8 products
: "Ecdysone-based system for controlled inducible expression of metabotropic glutamate receptor subtypes 2, 5, and 8." in: Journal of biomolecular screening, Vol. 10, Issue 8, pp. 841-8, (2006) (PubMed).Synonyms and alternative names related to GRM8
glutamate metabotropic receptor 8 (GRM8), metabotropic glutamate receptor 8 (MGLUR8), metabotropic glutamate receptor 8 (LOAG_14062), glutamate receptor, metabotropic 8 (Grm8), glutamate metabotropic receptor 8 (Grm8), A230002O04, GLUR8, Glur8, GPRC1H, Gprc1h, GRM8, mGlu8, mGlur, mGluR8, MGLUR8, Mglur8, mGluR8bProtein level used designations for GRM8
- metabotropic glutamate receptor 8
- metabotropic type glutamate receptor 8
- glutamate receptor, metabotropic 8
- G protein coupled receptor, family C, group 1, member H
- G protein-coupled receptor, family C, group 1, member H
- G protein-coupled receptor family C group 1 member H
- metabotropic glutamate receptor subtype 8b
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