GRM7 Products
(Glutamate Receptor, Metabotropic 7 (GRM7))
Categories
L-glutamate is the major excitatory neurotransmitter in the central nervous system, and it activates both ionotropic and metabotropic glutamate receptors. Glutamatergic neurotransmission is involved in most aspects of normal brain function and can be perturbed in many neuropathologic conditions. The metabotropic glutamate receptors are a family of G protein-coupled receptors that have been divided into three groups on the basis of sequence homology, putative signal transduction mechanisms, and pharmacologic properties. Group I includes GRM1 and GRM5, and these receptors have been shown to activate phospholipase C. Group II includes GRM2 and GRM3, while Group III includes GRM4, GRM6, GRM7 and GRM8. Group II and III receptors are linked to the inhibition of the cyclic AMP cascade but differ in their agonist selectivities. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jun 2009].
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Featured GRM7 Categories
GRM7 Antibodies
High quality antibodies with extensive validation data.
GRM7 ELISA Kits
Reliable ELISA kits for a wide range of species.
GRM7 Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended GRM7 Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
ELISA, FACS
Validations
- (4)
Cat. No.
ABIN5611160
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human, Mouse, Rat
Application
WB, ELISA, IHC, IF, ICC
Validations
- (3)
Cat. No.
ABIN6263242
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Cow, Dog, Horse, Human, Monkey, Mouse, Rat
Application
WB, IHC, IHC (p)
Validations
- (3)
Cat. No.
ABIN1048941
Quantity
50 μg
Datasheet
Datasheet
Recommended GRM7 ELISA Kits
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human, Mouse, Rat
Analytical Method
Qualitative Cell ELISA
Validations
Cat. No.
ABIN1381316
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Human
Analytical Method
Quantitative Competition ELISA
Validations
Cat. No.
ABIN1743305
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Sheep
Analytical Method
Validations
Cat. No.
ABIN1774210
Quantity
96 tests
Datasheet
Datasheet
Recommended GRM7 Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
HEK-293 Cells
Validations
- (2)
Cat. No.
ABIN7491677
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1355787
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1355786
Quantity
25 μg
Datasheet
Datasheet
Latest Publications for our GRM7 products
: "Localization of kainate receptors in inner and outer hair cell synapses." in: Hearing research, Vol. 314, pp. 20-32, (2014) (PubMed).: "GRM7 variants confer susceptibility to age-related hearing impairment. ..." in: Human molecular genetics, Vol. 18, Issue 4, pp. 785-96, (2009) (PubMed).
: "Glutamate receptor metabotropic 7 is cis-regulated in the mouse brain and modulates alcohol drinking." in: Genomics, Vol. 90, Issue 6, pp. 690-702, (2007) (PubMed).
: "Characterization of three novel isoforms of the metabotrobic glutamate receptor 7 (GRM7)." in: Neuroscience letters, Vol. 326, Issue 1, pp. 37-40, (2002) (PubMed).
Synonyms and alternative names related to GRM7
glutamate metabotropic receptor 7 (GRM7), glutamate receptor, metabotropic 7 (Grm7), glutamate metabotropic receptor 7 (Grm7), 6330570A01Rik, BB176677, C030018L03, E130018M02Rik, GLUR7, Gpr1g, GPRC1G, Gprc1g, MGLU7, MGLUR7, mGluR7Protein level used designations for GRM7
- metabotropic glutamate receptor 7
- mGluR7
- G protein-coupled receptor GRM7
- G protein-coupled receptor, family C, group 1, member G
- mGlu7a receptor
- metabotropic glutamate receptor mGluR7
- metabotropic glutamate receptor subtype 7b
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