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GRK6 Products

(G Protein-Coupled Receptor Kinase 6 (GRK6))

Categories

This gene encodes a member of the guanine nucleotide-binding protein (G protein)-coupled receptor kinase subfamily of the Ser/Thr protein kinase family. The protein phosphorylates the activated forms of G protein-coupled receptors thus initiating their deactivation. Several transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Jul 2008].

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Featured GRK6 Categories

GRK6 Antibodies

High quality antibodies with extensive validation data.

GRK6 Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended GRK6 Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, ELISA
Validations
  • (5)
Cat. No. ABIN561112
Quantity 100 μg
Datasheet Datasheet
Reactivity Human, Rat
Application WB
Validations
  • (1)
  • (1)
  • (1)
Cat. No. ABIN3042435
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application WB, ELISA
Validations
  • (1)
  • (3)
Cat. No. ABIN561115
Quantity 100 μg
Datasheet Datasheet

Recommended GRK6 Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1355769
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1355768
Quantity 25 μg
Datasheet Datasheet
Reactivity Human
Source Baculovirus infected Insect Cells
Validations
  • (1)
Cat. No. ABIN7317064
Quantity 50 μg
Datasheet Datasheet

Latest Publications for our GRK6 products

Reichel, Weitzel, Klement, Hoffmann, Drube: "Suitability of GRK Antibodies for Individual Detection and Quantification of GRK Isoforms in Western Blots." in: International journal of molecular sciences, Vol. 23, Issue 3, (2022) (PubMed).

Oda, Tadokoro, Takase, Kanahara, Watanabe, Shirayama, Hashimoto, Iyo: "G protein-coupled receptor kinase 6/?-arrestin 2 system in a rat model of dopamine supersensitivity psychosis." in: Journal of psychopharmacology (Oxford, England), (2015) (PubMed).

McCormick, Segarra, Gasperini, Gulino, Tosato: "Impaired recruitment of Grk6 and beta-Arrestin 2 causes delayed internalization and desensitization of a WHIM syndrome-associated CXCR4 mutant receptor." in: PLoS ONE, Vol. 4, Issue 12, pp. e8102, (2009) (PubMed).

Teli, Markovic, Levine, Hillhouse, Grammatopoulos et al.: "Regulation of corticotropin-releasing hormone receptor type 1alpha signaling: structural determinants for G protein-coupled receptor kinase-mediated phosphorylation and agonist-mediated ..." in: Molecular endocrinology (Baltimore, Md.), Vol. 19, Issue 2, pp. 474-90, (2005) (PubMed).

Hagen, Kondyra, Grocott, El-Moalem, Bainbridge, Mathew, Newman, Reves, Schwinn, Kwatra: "Cardiopulmonary bypass decreases G protein-coupled receptor kinase activity and expression in human peripheral blood mononuclear cells." in: Anesthesiology, Vol. 98, Issue 2, pp. 343-8, (2003) (PubMed).

Miyagawa, Ohguro, Odagiri, Maruyama, Maeda, Maeda, Sasaki, Nakazawa: "Aberrantly expressed recoverin is functionally associated with G-protein-coupled receptor kinases in cancer cell lines." in: Biochemical and biophysical research communications, Vol. 300, Issue 3, pp. 669-73, (2002) (PubMed).

Strausberg, Feingold, Grouse, Derge, Klausner, Collins, Wagner, Shenmen, Schuler, Altschul, Zeeberg, Buetow, Schaefer, Bhat, Hopkins, Jordan, Moore, Max, Wang, Hsieh, Diatchenko, Marusina, Farmer et al.: "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. ..." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 99, Issue 26, pp. 16899-903, (2002) (PubMed).

Synonyms and alternative names related to GRK6

G protein-coupled receptor kinase 6 (GRK6), G protein-coupled receptor kinase 6 S homeolog (grk6.S), G protein-coupled receptor kinase 6 (grk6), G protein-coupled receptor kinase 6 (Grk6), GPRK6, Gprk6, GRK6, MGC83187

Protein level used designations for GRK6

  • G protein-coupled receptor kinase 6
  • G protein-coupled receptor kinase 6-like
  • g protein-coupled receptor kinase GRK6
  • G-protein coupled receptor kinase 6
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