GRID2 Products
(Glutamate Receptor, Ionotropic, delta 2 (GRID2))
Categories
Human glutamate receptor delta-2 (GRID2) is a relatively new member of the family of ionotropic glutamate receptors which are the predominant excitatory neurotransmitter receptors in the mammalian brain. GRID2 is a predicted 1,007 amino acid protein that shares 97% identity with the mouse homolog which is expressed selectively in cerebellar Purkinje cells. A point mutation in mouse GRID2, associated with the phenotype named 'lurcher', in the heterozygous state leads to ataxia resulting from selective, cell-autonomous apoptosis of cerebellar Purkinje cells during postnatal development. Mice homozygous for this mutation die shortly after birth from massive loss of mid- and hindbrain neurons during late embryogenesis. This strongly suggests a role for GRID2 in neuronal apoptotic death. [provided by RefSeq, Jul 2008].
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Featured GRID2 Categories
GRID2 Antibodies
High quality antibodies with extensive validation data.
GRID2 ELISA Kits
Reliable ELISA kits for a wide range of species.
GRID2 Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended GRID2 Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human, Mouse, Rat
Application
WB, IF, ELISA, ICC, IHC
Validations
- (3)
Cat. No.
ABIN6257247
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, ELISA
Validations
- (2)
Cat. No.
ABIN561131
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Application
WB, IF, ELISA
Validations
- (1)
Cat. No.
ABIN7184958
Quantity
100 μg
Datasheet
Datasheet
Recommended GRID2 ELISA Kits
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6956153
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Human
Analytical Method
Quantitative Competition ELISA
Validations
Cat. No.
ABIN1503169
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Mouse
Analytical Method
Quantitative Competition ELISA
Validations
Cat. No.
ABIN1503171
Quantity
96 tests
Datasheet
Datasheet
Recommended GRID2 Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1355734
Quantity
10 μg
Datasheet
Datasheet
Latest Publications for our GRID2 products
: "Differential localization of delta glutamate receptors in the rat cerebellum: coexpression with AMPA receptors in parallel fiber-spine synapses and absence from climbing fiber-spine synapses." in: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 17, Issue 2, pp. 834-42, (1997) (PubMed).: "Neurodegeneration in Lurcher mice caused by mutation in delta2 glutamate receptor gene." in: Nature, Vol. 388, Issue 6644, pp. 769-73, (1997) (PubMed).
: "Suppression of LTD in cultured Purkinje cells deficient in the glutamate receptor delta 2 subunit." in: Neuroreport, Vol. 6, Issue 3, pp. 524-6, (1995) (PubMed).
: "Impairment of motor coordination, Purkinje cell synapse formation, and cerebellar long-term depression in GluR delta 2 mutant mice." in: Cell, Vol. 81, Issue 2, pp. 245-52, (1995) (PubMed).
: "Selective expression of the glutamate receptor channel delta 2 subunit in cerebellar Purkinje cells." in: Biochemical and biophysical research communications, Vol. 197, Issue 3, pp. 1267-76, (1994) (PubMed).
Synonyms and alternative names related to GRID2
glutamate receptor, ionotropic, delta 2 (grid2), glutamate receptor ionotropic, delta-2 (LOC704787), glutamate ionotropic receptor delta type subunit 2 (GRID2), glutamate receptor, ionotropic, delta 2 (Grid2), glutamate ionotropic receptor delta type subunit 2 (Grid2), glutamate receptor ionotropic, delta-2 (LOC536367), B230104L07Rik, cpr, GluD2, glurd2, GluRdelta2, GRID2, ho, Lc, LcProtein level used designations for GRID2
- gluR delta-2 subunit
- glutamate receptor delta-2 subunit
- glutamate receptor ionotropic, delta-2
- glutamate receptor, ionotropic, delta 2
- glutamate receptor delta-2 subunit-like
- GluR-delta-2
- creeper
- hotfoot
- lurcher
- minisatellite 10ac detected by probe MMS10
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