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GRHL2 Products

(Grainyhead-Like 2 (GRHL2))

Categories

The protein encoded by this gene is a transcription factor that can act as a homodimer or as a heterodimer with either GRHL1 or GRHL3. Defects in this gene are a cause of non-syndromic sensorineural deafness autosomal dominant type 28 (DFNA28).[provided by RefSeq, Mar 2009].

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Featured GRHL2 Categories

GRHL2 Antibodies

High quality antibodies with extensive validation data.

GRHL2 Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended GRHL2 Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, IF
Validations
  • (2)
  • (3)
Cat. No. ABIN529152
Quantity 50 μg
Datasheet Datasheet
Reactivity Human
Application ELISA, IHC, IF
Validations
  • (3)
Cat. No. ABIN7154376
Quantity 100 μg
Datasheet Datasheet

Application WB, IHC, IHC (p)
Validations
  • (3)
Cat. No. ABIN6744427
Quantity 100 μL
Datasheet Datasheet

Recommended GRHL2 Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1355716
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1355718
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Tobacco (Nicotiana tabacum)
Validations
Cat. No. ABIN3092858
Quantity 1 mg
Datasheet Datasheet

Latest Publications for our GRHL2 products

Mehrazarin, Chen, Oh, Liu, Kang, Yi, Kim, Shin, Park, Kang: "The p63 Gene Is Regulated by Grainyhead-like 2 (GRHL2) through Reciprocal Feedback and Determines the Epithelial Phenotype in Human Keratinocytes." in: The Journal of biological chemistry, Vol. 290, Issue 32, pp. 19999-20008, (2015) (PubMed).

Quan, Xu, Cui, Ye, Zhuang, Min: "Grainyhead-like 2 Promotes Tumor Growth and is Associated with Poor Prognosis in Colorectal Cancer." in: Journal of Cancer, Vol. 6, Issue 4, pp. 342-50, (2015) (PubMed).

Varma, Mahavadi, Sasikumar, Cushing, Hyland, Rosser, Riccardi, Lu, Kalin, Kalinichenko, Guenther, Ramirez, Pardo, Selman, Warburton: "Grainyhead-like 2 (GRHL2) distribution reveals novel pathophysiological differences between human idiopathic pulmonary fibrosis and mouse models of pulmonary fibrosis." in: American journal of physiology. Lung cellular and molecular physiology, Vol. 306, Issue 5, pp. L405-19, (2014) (PubMed).

Quan, Jin, Huang, Zhao, Feng, Zang, Zheng: "Downregulation of GRHL2 inhibits the proliferation of colorectal cancer cells by targeting ZEB1." in: Cancer biology & therapy, Vol. 15, Issue 7, pp. 878-87, (2014) (PubMed).

Butz, Szabó, Nofech-Mozes, Rotondo, Kovacs, Mirham, Girgis, Boles, Patocs, Yousef: "Integrative bioinformatics analysis reveals new prognostic biomarkers of clear cell renal cell carcinoma." in: Clinical chemistry, Vol. 60, Issue 10, pp. 1314-26, (2014) (PubMed).

Torres-Reyes, Alvarado-Ruiz, Piña-Sánchez, Martínez-Silva, Ramos-Solano, Olimón-Andalón, Ortiz-Lazareno, Hernández-Flores, Bravo-Cuellar, Aguilar-Lemarroy, Jave-Suarez: "Expression of transcription factor grainyhead-like 2 is diminished in cervical cancer." in: International journal of clinical and experimental pathology, Vol. 7, Issue 11, pp. 7409-18, (2014) (PubMed).

Werner, Frey, Riethdorf, Schulze, Alawi, Kling, Vafaizadeh, Sauter, Terracciano, Schumacher, Pantel, Assmann: "Dual roles of the transcription factor grainyhead-like 2 (GRHL2) in breast cancer." in: The Journal of biological chemistry, Vol. 288, Issue 32, pp. 22993-3008, (2013) (PubMed).

Cieply, Farris, Denvir, Ford, Frisch: "Epithelial-mesenchymal transition and tumor suppression are controlled by a reciprocal feedback loop between ZEB1 and Grainyhead-like-2." in: Cancer research, Vol. 73, Issue 20, pp. 6299-309, (2013) (PubMed).

Gao, Vockley, Pauli, Newberry, Xue, Randell, Reddy, Hogan: "Evidence for multiple roles for grainyhead-like 2 in the establishment and maintenance of human mucociliary airway epithelium.[corrected]." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 110, Issue 23, pp. 9356-61, (2013) (PubMed).

Chen, Xiao Liu, Oh, Shin, Kim, Jiang, Park, Kang: "Grainyhead-like 2 (GRHL2) inhibits keratinocyte differentiation through epigenetic mechanism." in: Cell death & disease, Vol. 3, pp. e450, (2012) (PubMed).

Synonyms and alternative names related to GRHL2

grainyhead-like transcription factor 2b (grhl2b), grainyhead like transcription factor 2 (GRHL2), grainyhead-like transcription factor 2 (Grhl2), grainyhead-like 2 (Drosophila) (Grhl2), grainyhead like transcription factor 2 (Grhl2), grainyhead-like transcription factor 2a (grhl2a), 0610015A08Rik, BOM, DFNA28, grhl2, GRHL2, RGD1561191, si:dkey-21k18.2, Tcfcp2l3, TFCP2L3, zgc:110324

Protein level used designations for GRHL2

  • grainyhead-like 2
  • grainyhead-like 2b protein
  • grainyhead-like protein 2 homolog
  • grainyhead-like 2 (Drosophila)
  • brother of mammalian grainyhead
  • transcription factor CP2-like 3
  • grainyhead like 2
  • grainyhead-like 2a
  • grainyhead-like transcription factor 2a
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