GRAP Products
(GRB2-Related Adaptor Protein (GRAP))
Categories
This gene encodes a member of the GRB2/Sem5/Drk family and functions as a cytoplasmic signaling protein which contains an SH2 domain flanked by two SH3 domains. The SH2 domain interacts with ligand-activated receptors for stem cell factor and erythropoietin, and facilitates the formation of a stable complex with the BCR-ABL oncoprotein. This protein also associates with the Ras guanine nucleotide exchange factor SOS1 (son of sevenless homolog 1) through its N-terminal SH3 domain. In general, it couples signals from receptor and cytoplasmic tyrosine kinases to the Ras signaling pathway. [provided by RefSeq, Jul 2012].
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Featured GRAP Categories
GRAP Antibodies
High quality antibodies with extensive validation data.
GRAP ELISA Kits
Reliable ELISA kits for a wide range of species.
GRAP Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended GRAP Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human, Mouse
Application
WB, ELISA, IHC, ICC, IF
Validations
- (3)
Cat. No.
ABIN6262074
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, ICC, IF, IHC (p)
Validations
- (3)
Cat. No.
ABIN2855869
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human, Mouse
Application
ELISA, IHC
Validations
- (2)
Cat. No.
ABIN7245824
Quantity
200 μL
Datasheet
Datasheet
Recommended GRAP ELISA Kits
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Analytical Method
Validations
Cat. No.
ABIN1135514
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Mouse
Analytical Method
Validations
Cat. No.
ABIN1135515
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Cow
Analytical Method
Validations
Cat. No.
ABIN1135513
Quantity
96 tests
Datasheet
Datasheet
Recommended GRAP Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1355690
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Tobacco (Nicotiana tabacum)
Validations
Cat. No.
ABIN3080886
Quantity
1 mg
Datasheet
Datasheet
Reactivity
Mouse
Source
Tobacco (Nicotiana tabacum)
Validations
Cat. No.
ABIN3128580
Quantity
1 mg
Datasheet
Datasheet
Latest Publications for our GRAP products
: "Efficient differentiation of human embryonic stem cells toward dopaminergic neurons using recombinant LMX1A factor." in: Molecular biotechnology, Vol. 57, Issue 2, pp. 184-94, (2015) (PubMed).: "The immunoglobulin tail tyrosine motif upgrades memory-type BCRs by incorporating a Grb2-Btk signalling module." in: Nature communications, Vol. 5, pp. 5456, (2014) (PubMed).
: "Grap is a novel SH3-SH2-SH3 adaptor protein that couples tyrosine kinases to the Ras pathway." in: The Journal of biological chemistry, Vol. 271, Issue 21, pp. 12129-32, (1996) (PubMed).
Synonyms and alternative names related to GRAP
GRB2-related adaptor protein (GRAP), GRB2-related adaptor protein (Grap), GRB2-related adapter protein (LOC489534), GRB2-related adaptor protein a (grapa), GRB2-related adaptor protein b (grapb), GRB2-related adapter protein (LOC100727005), 8430435N19Rik, BB233594, GRAP, grap, Grap, MGC109892, si:dkeyp-9d4.1, zgc:110202Protein level used designations for GRAP
- GRB2-related adapter protein
- growth factor receptor-bound protein 2-related adaptor protein
- GRB2-related adaptor protein
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