GPX4 Products
(Glutathione Peroxidase 4 (GPX4))
Categories
Glutathione peroxidase catalyzes the reduction of hydrogen peroxide, organic hydroperoxide, and lipid peroxides by reduced glutathione and functions in the protection of cells against oxidative damage. Human plasma glutathione peroxidase has been shown to be a selenium-containing enzyme and the UGA codon is translated into a selenocysteine. Through alternative splicing and transcription initiation, rat produces proteins that localize to the nucleus, mitochondrion, and cytoplasm. In humans, experimental evidence for alternative splicing exists\; alternative transcription initiation and the cleavage sites of the mitochondrial and nuclear transit peptides need to be experimentally verified. [provided by RefSeq, Jul 2008].
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Featured GPX4 Categories
GPX4 Antibodies
High quality antibodies with extensive validation data.
GPX4 ELISA Kits
Reliable ELISA kits for a wide range of species.
GPX4 Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended GPX4 Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB, IHC, IP, IF
Validations
- (1)
- (8)
Cat. No.
ABIN3015730
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, IHC, IP, ICC
Validations
- (9)
Cat. No.
ABIN7438652
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Mouse
Application
WB, IHC, IP, ICC
Validations
- (4)
Cat. No.
ABIN7439558
Quantity
100 μL
Datasheet
Datasheet
Recommended GPX4 ELISA Kits
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6956199
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Mouse
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6975523
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Rat
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6975657
Quantity
96 tests
Datasheet
Datasheet
Recommended GPX4 Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
- (1)
Cat. No.
ABIN7123131
Quantity
50 μg
Datasheet
Datasheet
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
Cat. No.
ABIN7403591
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Mouse
Source
Escherichia coli (E. coli)
Validations
Cat. No.
ABIN7404995
Quantity
100 μg
Datasheet
Datasheet
Latest Publications for our GPX4 products
: "Physiological functions of ferroportin in the regulation of renal iron recycling and ischemic acute kidney injury." in: American journal of physiology. Renal physiology, Vol. 315, Issue 4, pp. F1042-F1057, (2018) (PubMed).: "The oxido-reductase enzyme glutathione peroxidase 4 (GPX4) governs Salmonella Typhimurium-induced neutrophil transepithelial migration." in: Cellular microbiology, Vol. 16, Issue 9, pp. 1339-53, (2014) (PubMed).
: "SECIS-binding protein 2 promotes cell survival by protecting against oxidative stress." in: Antioxidants & redox signaling, Vol. 12, Issue 7, pp. 797-808, (2010) (PubMed).
: "Mutations in the selenocysteine insertion sequence-binding protein 2 gene lead to a multisystem selenoprotein deficiency disorder in humans. ..." in: The Journal of clinical investigation, Vol. 120, Issue 12, pp. 4220-35, (2010) (PubMed).
: "Post-transcriptional regulation of mRNA associated with DJ-1 in sporadic Parkinson disease." in: Neuroscience letters, Vol. 452, Issue 1, pp. 8-11, (2009) (PubMed).
: "Mammalian selenoprotein thioredoxin-glutathione reductase. Roles in disulfide bond formation and sperm maturation." in: The Journal of biological chemistry, Vol. 280, Issue 28, pp. 26491-8, (2005) (PubMed).
: "Role of mitochondrial phospholipid hydroperoxide glutathione peroxidase (PHGPx) as an antiapoptotic factor." in: Biological & pharmaceutical bulletin, Vol. 27, Issue 7, pp. 956-60, (2004) (PubMed).
: "A comparative study on the hydroperoxide and thiol specificity of the glutathione peroxidase family and selenoprotein P." in: The Journal of biological chemistry, Vol. 277, Issue 43, pp. 41254-8, (2002) (PubMed).
Synonyms and alternative names related to GPX4
glutathione peroxidase 4 (GPX4), glutathione peroxidase 4 (Gpx4), glutathione peroxidase 4a (gpx4a), 1700027O09Rik, ATGPX4, cb563, cb691, F11L15.5, glutathione peroxidase 4, GP-GPx4, GPx-4, gpx-4, GSHPx-4, MCSP, mtPHGPx, PHGPx, Phgpx, PHGPxa, sb:cb563, snGPx, snGpx, snPHGPx, wu:fb82e03, zgc:92253Protein level used designations for GPX4
- phospholipid hydroperoxidase
- phospholipid hydroperoxide glutathione peroxidase, mitochondrial
- sperm nucleus glutathione peroxidase
- GSHPx-4
- phospholipid hydroperoxide glutathione peroxidase, nuclear
- glutathione peroxidase 4
- GPx-4
- sperm nuclei glutathione peroxidase
- glutathione peroxidase 4 (phospholipid hydroperoxidase)
- phospholipid hydroperoxide glutathione peroxidase
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