GPS2 Products
(G Protein Pathway Suppressor 2 (GPS2))
Categories
This gene encodes a protein involved in G protein-mitogen-activated protein kinase (MAPK) signaling cascades. When overexpressed in mammalian cells, this gene could potently suppress a RAS- and MAPK-mediated signal and interfere with JNK activity, suggesting that the function of this gene may be signal repression. The encoded protein is an integral subunit of the NCOR1-HDAC3 (nuclear receptor corepressor 1-histone deacetylase 3) complex, and it was shown that the complex inhibits JNK activation through this subunit and thus could potentially provide an alternative mechanism for hormone-mediated antagonism of AP1 (activator protein 1) function. [provided by RefSeq, Jul 2008].
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Featured GPS2 Categories
GPS2 Antibodies
High quality antibodies with extensive validation data.
GPS2 Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended GPS2 Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB, ELISA
Validations
- (1)
- (3)
Cat. No.
ABIN561119
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Application
WB, ELISA
Validations
- (1)
Cat. No.
ABIN7188791
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Application
ELISA, IF
Validations
- (1)
Cat. No.
ABIN7153281
Quantity
100 μg
Datasheet
Datasheet
Recommended GPS2 ELISA Kits
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
Cat. No.
ABIN6204554
Quantity
96 tests
Datasheet
Datasheet
Recommended GPS2 Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1355662
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1355661
Quantity
25 μg
Datasheet
Datasheet
Reactivity
Human
Source
Tobacco (Nicotiana tabacum)
Validations
Cat. No.
ABIN3080928
Quantity
1 mg
Datasheet
Datasheet
Latest Publications for our GPS2 products
: "Involvement of corepressor complex subunit GPS2 in transcriptional pathways governing human bile acid biosynthesis." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 104, Issue 40, pp. 15665-70, (2007) (PubMed).: "The N-CoR-HDAC3 nuclear receptor corepressor complex inhibits the JNK pathway through the integral subunit GPS2." in: Molecular cell, Vol. 9, Issue 3, pp. 611-23, (2002) (PubMed).
: "Gps2, a protein partner for human papillomavirus E6 proteins." in: Journal of virology, Vol. 75, Issue 1, pp. 151-60, (2001) (PubMed).
: "AMF-1/Gps2 binds p300 and enhances its interaction with papillomavirus E2 proteins." in: Journal of virology, Vol. 74, Issue 13, pp. 5872-9, (2000) (PubMed).
Synonyms and alternative names related to GPS2
G protein pathway suppressor 2 (gps2), G protein pathway suppressor 2 L homeolog (gps2.L), G protein pathway suppressor 2 (GPS2), G protein pathway suppressor 2 (Gps2), AI505953, amf-1, AMF-1, gps2, GPS2, MGC63588, MGC68832, MGC133909, zgc:63588Protein level used designations for GPS2
- G protein pathway suppressor 2
- G-protein pathway suppressor 2
- GPS-2
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