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GPR56 Products

(G Protein-Coupled Receptor 56 (GPR56))

Categories

This gene encodes a member of the G protein-coupled receptor family. The protein contains 7 transmembrane domains and a mucin-like domain in the N-terminal region. The gene is implicated in the regulation of brain cortical patterning. The protein binds specifically to transglutaminase 2 in the extracellular space. Expression of this gene is downregulated in melanoma cell lines, and overexpression of this gene can suppress tumor growth and metastasis. Mutations in this gene result in bilateral frontoparietal polymicrogyria. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2009].

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Featured GPR56 Categories

GPR56 Antibodies

High quality antibodies with extensive validation data.

GPR56 Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended GPR56 Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, FACS
Validations
  • (4)
Cat. No. ABIN522766
Quantity 50 μg
Datasheet Datasheet
Reactivity Human
Application WB, ELISA, IHC
Validations
  • (2)
Cat. No. ABIN6258204
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Monkey
Application IHC, IHC (p)
Validations
  • (2)
Cat. No. ABIN1048840
Quantity 50 μg
Datasheet Datasheet

Recommended GPR56 ELISA Kits

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
Cat. No. ABIN4883128
Quantity 96 tests
Datasheet Datasheet
Reactivity Human
Analytical Method Semi-Quantitative Sandwich ELISA
Validations
Cat. No. ABIN6385567
Quantity 96 tests
Datasheet Datasheet

Recommended GPR56 Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source HEK-293 Cells
Validations
  • (1)
Cat. No. ABIN7491385
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1788443
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1355626
Quantity 10 μg
Datasheet Datasheet

Latest Publications for our GPR56 products

Stoveken, Hajduczok, Xu, Tall: "Adhesion G protein-coupled receptors are activated by exposure of a cryptic tethered agonist." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 112, Issue 19, pp. 6194-9, (2015) (PubMed).

Yang, Friedland, Corson, Xu: "GPR56 inhibits melanoma growth by internalizing and degrading its ligand TG2." in: Cancer research, Vol. 74, Issue 4, pp. 1022-31, (2014) (PubMed).

Chiang, Hsiao, Huang, Chen, Hsieh, Chang, Lin: "Disease-associated GPR56 mutations cause bilateral frontoparietal polymicrogyria via multiple mechanisms." in: The Journal of biological chemistry, Vol. 286, Issue 16, pp. 14215-25, (2011) (PubMed).

Paavola, Stephenson, Ritter, Alter, Hall: "The N terminus of the adhesion G protein-coupled receptor GPR56 controls receptor signaling activity." in: The Journal of biological chemistry, Vol. 286, Issue 33, pp. 28914-21, (2011) (PubMed).

Synonyms and alternative names related to GPR56

adhesion G protein-coupled receptor G1 (ADGRG1), adhesion G protein-coupled receptor G1 (adgrg1), adhesion G protein-coupled receptor G1 (Adgrg1), G protein-coupled receptor 56 (GPR56), BFPP, Cyt28, fc49b10, GPR56, TM7LN4, TM7XN1, wu:fc49b10

Protein level used designations for GPR56

  • G protein-coupled receptor 56
  • G-protein coupled receptor 56-like
  • 7-transmembrane protein with no EGF-like N-terminal domains-1
  • G-protein coupled receptor 56
  • secretin receptor
  • serpentine receptor cyt28
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