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GPI Products

(Glucose-6-Phosphate Isomerase (GPI))

Categories

This gene belongs to the GPI family whose members encode multifunctional phosphoglucose isomerase proteins involved in energy pathways. The protein encoded by this gene is a dimeric enzyme that catalyzes the reversible isomerization of glucose-6-phosphate and fructose-6-phosphate. The protein functions in different capacities inside and outside the cell. In the cytoplasm, the gene product is involved in glycolysis and gluconeogenesis, while outside the cell it functions as a neurotrophic factor for spinal and sensory neurons. Defects in this gene are the cause of nonspherocytic hemolytic anemia and a severe enzyme deficiency can be associated with hydrops fetalis, immediate neonatal death and neurological impairment. [provided by RefSeq, Jul 2008].

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Featured GPI Categories

GPI Antibodies

High quality antibodies with extensive validation data.

GPI ELISA Kits

Reliable ELISA kits for a wide range of species.

GPI Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended GPI Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, ELISA, IHC, IF, IP
Validations
  • (5)
Cat. No. ABIN7153928
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application WB, ELISA, IHC
Validations
  • (5)
Cat. No. ABIN571080
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application WB, ELISA, IHC, ICC
Validations
  • (3)
  • (4)
Cat. No. ABIN969176
Quantity 100 μL
Datasheet Datasheet

Recommended GPI ELISA Kits

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
  • (1)
Cat. No. ABIN6956126
Quantity 96 tests
Datasheet Datasheet
Reactivity Mouse
Analytical Method Quantitative Sandwich ELISA
Validations
  • (2)
  • (1)
Cat. No. ABIN6956127
Quantity 96 tests
Datasheet Datasheet
Reactivity Rat
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6967039
Quantity 96 tests
Datasheet Datasheet

Recommended GPI Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
  • (1)
Cat. No. ABIN7123106
Quantity 50 μg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1355542
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1355544
Quantity 10 μg
Datasheet Datasheet

Latest Publications for our GPI products

Guo, Jiang, Yu, Niu, Liu, Zhou, Zhang, Li, Zhu, Zhou, Sha, Guo, Chen: "Proteomics analysis of asthenozoospermia and identification of glucose-6-phosphate isomerase as an important enzyme for sperm motility." in: Journal of proteomics, Vol. 208, pp. 103478, (2020) (PubMed).

Sio, Anantharaman, Lee, Matta, Ng, Chew: "The Asthma-associated PER1-like domain-containing protein 1 (PERLD1) Haplotype Influences Soluble Glycosylphosphatidylinositol Anchor Protein (sGPI-AP) Levels in Serum and Immune Cell Proliferation." in: Scientific reports, Vol. 10, Issue 1, pp. 715, (2020) (PubMed).

Liu, Zhao, Zheng, Zhu, Cui, Cao: "The Glycosylphosphatidylinositol Transamidase Complex Subunit PbGPI16 of Plasmodium berghei Is Important for Inducing Experimental Cerebral Malaria." in: Infection and immunity, Vol. 86, Issue 8, (2019) (PubMed).

Nyhoff, Barron, Johnson, Bonami, Maseda, Fensterheim, Han, Blackwell, Crofford, Kendall: "Bruton's Tyrosine Kinase Deficiency Inhibits Autoimmune Arthritis in Mice but Fails to Block Immune Complex-Mediated Inflammatory Arthritis." in: Arthritis & rheumatology (Hoboken, N.J.), Vol. 68, Issue 8, pp. 1856-68, (2016) (PubMed).

Jiang, Wang, Wang, Xu, Xu, Tang, Sun, Wang, Zhang: "Enolase1 (ENO1) and glucose-6-phosphate isomerase (GPI) are good markers to predict human sperm freezability." in: Cryobiology, Vol. 71, Issue 1, pp. 141-5, (2015) (PubMed).

Zhao, Li, Liao, Luo, Shi, Feng, Chen: "Evodiamine Induces Apoptosis and Inhibits Migration of HCT-116 Human Colorectal Cancer Cells." in: International journal of molecular sciences, Vol. 16, Issue 11, pp. 27411-21, (2015) (PubMed).

Lucarelli, Galleggiante, Rutigliano, Sanguedolce, Cagiano, Bufo, Lastilla, Maiorano, Ribatti, Giglio, Serino, Vavallo, Bettocchi, Selvaggi, Battaglia, Ditonno: "Metabolomic profile of glycolysis and the pentose phosphate pathway identifies the central role of glucose-6-phosphate dehydrogenase in clear cell-renal cell carcinoma." in: Oncotarget, Vol. 6, Issue 15, pp. 13371-86, (2015) (PubMed).

Lucarelli, Rutigliano, Sanguedolce, Galleggiante, Giglio, Cagiano, Bufo, Maiorano, Ribatti, Ranieri, Gigante, Gesualdo, Ferro, de Cobelli, Buonerba, Di Lorenzo, De Placido, Palazzo, Bettocchi et al.: "Increased Expression of the Autocrine Motility Factor is Associated With Poor Prognosis in Patients With Clear Cell-Renal Cell Carcinoma. ..." in: Medicine, Vol. 94, Issue 46, pp. e2117, (2015) (PubMed).

Nakajima, Yanagawa, Watanabe, Takagishi: "Hyperthermia reduces migration of osteosarcoma by suppression of autocrine motility factor." in: Oncology reports, Vol. 28, Issue 6, pp. 1953-8, (2012) (PubMed).

Benveniste, Frelin, Janmohamed, Barbara, Herrington, Hyam, Iscove: "Intermediate-term hematopoietic stem cells with extended but time-limited reconstitution potential." in: Cell stem cell, Vol. 6, Issue 1, pp. 48-58, (2010) (PubMed).

Synonyms and alternative names related to GPI

glucose-6-phosphate isomerase (GPI), glucose-6-phosphate isomerase (Gpi), glucose-6-phosphate isomerase (gpi), gpi (pgi), glucose-6-phosphate isomerase 1 (GPI1), gpi Glucose-6-phosphate isomerase (gpi), Phosphoglucose isomerase (Pgi), glucose phosphate isomerase 1 (Gpi1), glucose-6-phosphate isomerase b (gpib), Amf, AMF, CG8251, DDBDRAFT_0185620, DDBDRAFT_0231026, DDB_0185620, DDB_0231026, Dmel\\CG8251, GNPI, GPI, Gpi, gpi, Gpi-1, Gpi-1r, Gpi-1s, Gpi-1t, Gpi1, Gpi1-r, Gpi1-s, Gpi1-t, Gpi1s, MF, NK, NK/GPI, NLK, Org, PGI, pgi, pgi-2, PHI, SA-36, SA36

Protein level used designations for GPI

  • AMF
  • NLK
  • PHI
  • autocrine motility factor
  • glucose phosphate isomerase
  • muscle phosphohexose isomerase
  • neuroleukin
  • phosphoglucose isomerase
  • phosphohexose isomerase
  • PGI
  • glucosephosphate isomerase
  • glucose-6-phosphate isomerase
  • gpi Glucose-6-phosphate isomerase
  • CG8251-PA
  • CG8251-PB
  • CG8251-PC
  • Pgi-PA
  • Pgi-PB
  • Pgi-PC
  • phosphoglucoisomerase
  • glucose phosphate isomerase 1 complex
  • glucose phosphate isomerase 1, regulatory
  • glucose phosphate isomerase 1, structural
  • glucose phosphate isomerase 1, temporal
  • maturation factor
  • structural glucose phosphate isomerase 1
  • hexose monophosphate isomerase
  • hexosephosphate isomerase
  • oxoisomerase
  • phosphohexomutase
  • phosphosaccharomutase
  • sperm antigen 36
  • sperm antigen-36
  • glucose phosphate isomerase b
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