GPBAR1 Products
(G Protein-Coupled Bile Acid Receptor 1 (GPBAR1))
Categories
This gene encodes a member of the G protein-coupled receptor (GPCR) superfamily. This enzyme functions as a cell surface receptor for bile acids. Treatment of cells expressing this GPCR with bile acids induces the production of intracellular cAMP, activation of a MAP kinase signaling pathway, and internalization of the receptor. The receptor is implicated in the suppression of macrophage functions and regulation of energy homeostasis by bile acids. Alternative splicing results in multiple transcript variants encoding the same protein. [provided by RefSeq, Jul 2008].
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Featured GPBAR1 Categories
GPBAR1 Antibodies
High quality antibodies with extensive validation data.
GPBAR1 ELISA Kits
Reliable ELISA kits for a wide range of species.
GPBAR1 Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended GPBAR1 Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB, IHC (p)
Validations
- (3)
Cat. No.
ABIN2857020
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
IHC, IHC (p)
Validations
- (2)
Cat. No.
ABIN1049401
Quantity
50 μg
Datasheet
Datasheet
Reactivity
Human
Application
ELISA, IF
Validations
Cat. No.
ABIN7189041
Quantity
100 μg
Datasheet
Datasheet
Recommended GPBAR1 ELISA Kits
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Rat
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6966916
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Rat
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6956015
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6973446
Quantity
96 tests
Datasheet
Datasheet
Recommended GPBAR1 Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1355520
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Mammalian Cells
Validations
Cat. No.
ABIN7538251
Quantity
50 μg
Datasheet
Datasheet
Reactivity
Mouse
Source
Tobacco (Nicotiana tabacum)
Validations
Cat. No.
ABIN3124225
Quantity
1 mg
Datasheet
Datasheet
Latest Publications for our GPBAR1 products
: "Lithocholic acid, a bacterial metabolite reduces breast cancer cell proliferation and aggressiveness." in: Biochimica et biophysica acta. Bioenergetics, Vol. 1859, Issue 9, pp. 958-974, (2018) (PubMed).: "Ginsenoside metabolite compound K stimulates glucagon-like peptide-1 secretion in NCI-H716 cells via bile acid receptor activation." in: Archives of pharmacal research, Vol. 37, Issue 9, pp. 1193-200, (2014) (PubMed).
: "Spergularia marina induces glucagon-like peptide-1 secretion in NCI-H716 cells through bile acid receptor activation." in: Journal of medicinal food, Vol. 17, Issue 11, pp. 1197-203, (2014) (PubMed).
: "TGR5 signalling inhibits the production of pro-inflammatory cytokines by in vitro differentiated inflammatory and intestinal macrophages in Crohn's disease." in: Immunology, Vol. 139, Issue 1, pp. 19-29, (2013) (PubMed).
: "Plasma bile acids are associated with energy expenditure and thyroid function in humans." in: The Journal of clinical endocrinology and metabolism, Vol. 97, Issue 2, pp. 535-42, (2012) (PubMed).
: "Activation of the bile acid receptor GPBAR1 protects against gastrointestinal injury caused by non-steroidal anti-inflammatory drugs and aspirin in mice." in: British journal of pharmacology, Vol. 168, Issue 1, pp. 225-37, (2012) (PubMed).
: "The receptor TGR5 mediates the prokinetic actions of intestinal bile acids and is required for normal defecation in mice." in: Gastroenterology, Vol. 144, Issue 1, pp. 145-54, (2012) (PubMed).
: "The bile acid receptor GPBAR-1 (TGR5) modulates integrity of intestinal barrier and immune response to experimental colitis." in: PLoS ONE, Vol. 6, Issue 10, pp. e25637, (2011) (PubMed).
Synonyms and alternative names related to GPBAR1
G protein-coupled bile acid receptor 1 (GPBAR1), G protein-coupled bile acid receptor 1 (Gpbar1), G protein-coupled bile acid receptor 1 S homeolog (gpbar1.S), BG37, GPBAR1, Gpbar1, GPCR, GPCR19, GPR131, M-BAR, MGC84403, TGR5, Tgr5Protein level used designations for GPBAR1
- G-protein coupled bile acid receptor 1
- G-protein coupled bile acid receptor BG37
- G-protein coupled receptor GPCR19
- hBG37
- hGPCR19
- membrane bile acid receptor
- membrane-type receptor for bile acids
- G protein-coupled receptor TGR5
- G protein-coupled receptor
- M-BAR
- G protein-coupled bile acid receptor 1
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