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GP6 Products

(Glycoprotein VI (Platelet) (GP6))
This gene encodes a platelet membrane glycoprotein of the immunoglobulin superfamily. The encoded protein is a receptor for collagen and plays a critical role in collagen-induced platelet aggregation and thrombus formation. The encoded protein forms a complex with the Fc receptor gamma-chain that initiates the platelet activation signaling cascade upon collagen binding. Mutations in this gene are a cause of platelet-type bleeding disorder-11 (BDPLT11). Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Dec 2011].

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Featured GP6 Categories

GP6 Antibodies

High quality antibodies with extensive validation data.

GP6 ELISA Kits

Reliable ELISA kits for a wide range of species.

GP6 Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended GP6 Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, IHC, IP, ICC
Validations
  • (4)
Cat. No. ABIN7434317
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application ELISA, IHC, IF
Validations
  • (3)
Cat. No. ABIN7163593
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application WB, FACS, IHC (p)
Validations
  • (3)
Cat. No. ABIN651878
Quantity 400 μL
Datasheet Datasheet

Recommended GP6 ELISA Kits

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
  • (1)
Cat. No. ABIN6956265
Quantity 96 tests
Datasheet Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6967157
Quantity 96 tests
Datasheet Datasheet
Reactivity Rat
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN4993472
Quantity 96 tests
Datasheet Datasheet

Recommended GP6 Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source HEK-293 Cells
Validations
  • (3)
Cat. No. ABIN7274760
Quantity 100 μg
Datasheet Datasheet
Reactivity Cynomolgus
Source HEK-293 Cells
Validations
  • (3)
Cat. No. ABIN7274759
Quantity 100 μg
Datasheet Datasheet
Reactivity Mouse
Source HEK-293 Cells
Validations
  • (2)
Cat. No. ABIN7274761
Quantity 100 μg
Datasheet Datasheet

Latest Publications for our GP6 products

Goetzl, Goetzl, Karliner, Tang, Pulliam: "Human plasma platelet-derived exosomes: effects of aspirin." in: FASEB journal : official publication of the Federation of American Societies for Experimental Biology, Vol. 30, Issue 5, pp. 2058-63, (2017) (PubMed).

Windeløv, Ostrowski, Johansson, Wanscher, Larsen, Sørensen, Rasmussen: "Circulating levels of platelet ?-granule cytokines in trauma patients." in: Inflammation research : official journal of the European Histamine Research Society ... [et al.], Vol. 64, Issue 3-4, pp. 235-41, (2015) (PubMed).

Lindsey, Jiang, Woulfe, Papoutsakis: "Platelets from mice lacking the aryl hydrocarbon receptor exhibit defective collagen-dependent signaling." in: Journal of thrombosis and haemostasis : JTH, Vol. 12, Issue 3, pp. 383-94, (2014) (PubMed).

Inoue, Suzuki-Inoue, Dean, Frampton, Watson: "Integrin alpha2beta1 mediates outside-in regulation of platelet spreading on collagen through activation of Src kinases and PLCgamma2." in: The Journal of cell biology, Vol. 160, Issue 5, pp. 769-80, (2003) (PubMed).

Jandrot-Perrus, Busfield, Lagrue, Xiong, Debili, Chickering, Le Couedic, Goodearl, Dussault, Fraser, Vainchenker, Villeval: "Cloning, characterization, and functional studies of human and mouse glycoprotein VI: a platelet-specific collagen receptor from the immunoglobulin superfamily." in: Blood, Vol. 96, Issue 5, pp. 1798-807, (2000) (PubMed).

Synonyms and alternative names related to GP6

glycoprotein VI platelet (GP6), glycoprotein 6 (platelet) (Gp6), glycoprotein VI (Gp6), glycoprotein VI platelet (Gp6), platelet glycoprotein VI (LOC103346235), 9830166G18Rik, BDPLT11, Gm469, GP6, GPIV, GPVI, Gpvi

Protein level used designations for GP6

  • glycoprotein 6
  • platelet collagen receptor
  • platelet glycoprotein VI
  • glycoprotein VI (platelet)
  • glycoprotein 5
  • glycoprotein 6 (platelet)
  • glycoprotein VI
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