GNRHR Products
(Gonadotropin-Releasing Hormone Receptor (GNRHR))
Categories
This gene encodes the receptor for type 1 gonadotropin-releasing hormone. This receptor is a member of the seven-transmembrane, G-protein coupled receptor (GPCR) family. It is expressed on the surface of pituitary gonadotrope cells as well as lymphocytes, breast, ovary, and prostate. Following binding of gonadotropin-releasing hormone, the receptor associates with G-proteins that activate a phosphatidylinositol-calcium second messenger system. Activation of the receptor ultimately causes the release of gonadotropic luteinizing hormone (LH) and follicle stimulating hormone (FSH). Defects in this gene are a cause of hypogonadotropic hypogonadism (HH). Alternative splicing results in multiple transcript variants encoding different isoforms. More than 18 transcription initiation sites in the 5' region and multiple polyA signals in the 3' region have been identified for this gene. [provided by RefSeq, Jul 2008].
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Featured GNRHR Categories
GNRHR Antibodies
High quality antibodies with extensive validation data.
GNRHR ELISA Kits
Reliable ELISA kits for a wide range of species.
GNRHR Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended GNRHR Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human, Rat
Application
WB, ELISA, IHC (p), IHC (fro), ICC, IF (cc), IF (p)
Validations
- (2)
- (5)
Cat. No.
ABIN686917
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human, Mouse
Application
WB, ELISA, IHC
Validations
- (3)
Cat. No.
ABIN7242191
Quantity
200 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, ELISA, FACS, IHC (fro)
Validations
- (4)
Cat. No.
ABIN966217
Quantity
0.5 mL
Datasheet
Datasheet
Recommended GNRHR ELISA Kits
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Rat
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6967187
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Mouse
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6967186
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6967185
Quantity
96 tests
Datasheet
Datasheet
Recommended GNRHR Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
HEK-293 Cells
Validations
- (1)
Cat. No.
ABIN6964191
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
Cat. No.
ABIN1330111
Quantity
2 μg
Datasheet
Datasheet
Reactivity
Rat
Source
Escherichia coli (E. coli)
Validations
Cat. No.
ABIN7394573
Quantity
100 μg
Datasheet
Datasheet
Latest Publications for our GNRHR products
: "Androgen receptor as a prognostic biomarker and therapeutic target in uterine leiomyosarcoma." in: Journal of gynecologic oncology, Vol. 29, Issue 3, pp. e30, (2019) (PubMed).: "The influence of dopaminergic system inhibition on biosynthesis of gonadotrophin-releasing hormone (GnRH) and GnRH receptor in anoestrous sheep; hierarchical role of kisspeptin and RFamide-related ..." in: Reproduction, fertility, and development, (2018) (PubMed).
: "Investigation of hormone receptor expression and its prognostic value in endometrial stromal sarcoma." in: Virchows Archiv : an international journal of pathology, Vol. 473, Issue 1, pp. 61-69, (2018) (PubMed).
: "The expression of several reproductive hormone receptors can be modified by perfluorooctane sulfonate (PFOS) in adult male rats." in: Chemosphere, Vol. 155, pp. 488-97, (2016) (PubMed).
: "Effects of di-(2-ethylhexyl) phthalate on the hypothalamus-pituitary-ovarian axis in adult female rats." in: Reproductive toxicology (Elmsford, N.Y.), Vol. 46, pp. 141-7, (2014) (PubMed).
: "Improvement of chloride transport defect by gonadotropin-releasing hormone (GnRH) in cystic fibrosis epithelial cells." in: PLoS ONE, Vol. 9, Issue 2, pp. e88964, (2014) (PubMed).
: "Inhibition of ovarian cancer growth by a tumor-targeting peptide that binds eukaryotic translation initiation factor 4E." in: Clinical cancer research : an official journal of the American Association for Cancer Research, Vol. 15, Issue 13, pp. 4336-47, (2009) (PubMed).
: "Expression and transcriptional regulation of the GnRH receptor gene in human neuronal cells." in: Molecular human reproduction, Vol. 11, Issue 11, pp. 837-42, (2006) (PubMed).
: "Characterization of a new upstream GnRH receptor promoter in human ovarian granulosa-luteal cells." in: Molecular endocrinology (Baltimore, Md.), Vol. 16, Issue 7, pp. 1552-64, (2002) (PubMed).
: "Endogenous regulation of the GnRH receptor by GnRH in the human placenta." in: Molecular human reproduction, Vol. 7, Issue 1, pp. 89-95, (2001) (PubMed).
Synonyms and alternative names related to GNRHR
gonadotropin releasing hormone receptor (GNRHR), gonadotropin releasing hormone receptor (Gnrhr), gonadotropin releasing hormone receptor (gnrhr), gonadotropin-releasing hormone receptor (gnrh-r), GH1, gnrh-r, GNRHR, GNRHR1, GNRHR1/III, GNRHR2, gnrhr3/ii, GRHR, HH7, LHRHR, Lhrhr, LRHR, xgnrhrProtein level used designations for GNRHR
- gnRH receptor
- gnRH-R
- gonadotropin-releasing hormone (type 1) receptor 1
- leutinizing hormone releasing horomone receptor
- leutinizing-releasing hormone receptor
- luliberin receptor
- type I GnRH receptor
- GnRH receptor
- gonadotropin-releasing hormone receptor
- gonadotropin releasing hormone receptor
- growth hormone
- luteinizing-releasing hormone receptor
- gnoadotropin releasing hormone receptor 2
- gonadotropin-releasing hormone II receptor
- type 1/III gonadotropin-releasing hormone receptor hexahelical
- type 3/II gonadotropin-releasing hormone receptor
- pituitary GnRH receptor
- pituitary gonadotropin-releasing hormone receptor
- LHRH
- luteinizing hormone-releasing hormone receptor
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