GNPTAB Products
(N-Acetylglucosamine-1-Phosphate Transferase, alpha and beta Subunits (GNPTAB))
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This gene encodes two of three subunit types of the membrane-bound enzyme N-acetylglucosamine-1-phosphotransferase, a heterohexameric complex composed of two alpha, two beta, and two gamma subunits. The encoded protein is proteolytically cleaved at the Lys928-Asp929 bond to yield mature alpha and beta polypeptides while the gamma subunits are the product of a distinct gene (GeneID 84572). In the Golgi apparatus, the heterohexameric complex catalyzes the first step in the synthesis of mannose 6-phosphate recognition markers on certain oligosaccharides of newly synthesized lysosomal enzymes. These recognition markers are essential for appropriate trafficking of lysosomal enzymes. Mutations in this gene have been associated with both mucolipidosis II and mucolipidosis IIIA.[provided by RefSeq, May 2010].
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Featured GNPTAB Categories
GNPTAB Antibodies
High quality antibodies with extensive validation data.
Recommended GNPTAB Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Bat, Cow, Dog, Guinea Pig, Horse, Human, Monkey, Mouse, Rabbit, Rat, Zebrafish (Danio rerio)
Application
WB
Validations
- (1)
Cat. No.
ABIN6745666
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB
Validations
- (1)
Cat. No.
ABIN7268770
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB
Validations
- (1)
Cat. No.
ABIN928289
Quantity
100 μL
Datasheet
Datasheet
Recommended GNPTAB ELISA Kits
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Rat
Analytical Method
Quantitative Sandwich ELISA
Validations
Cat. No.
ABIN6229857
Quantity
96 tests
Datasheet
Datasheet
Synonyms and alternative names related to GNPTAB
N-acetylglucosamine-1-phosphate transferase alpha and beta subunits (GNPTAB), N-acetylglucosamine-1-phosphate transferase, alpha and beta subunits (gnptab), N-acetylglucosamine-1-phosphotransferase subunits alpha/beta (LOC100175423), N-acetylglucosamine-1-phosphate transferase alpha and beta subunits (gnptab), N-acetylglucosamine-1-phosphate transferase, alpha and beta subunits (Gnptab), EG432486, GNPTA, ICD, mKIAA1208, RGD1564821, si:ch211-234f20.3, wu:fd55d09, zgc:122985, zgc:158502Protein level used designations for GNPTAB
- N-acetylglucosamine-1-phosphate transferase, alpha and beta subunits
- N-acetylglucosamine-1-phosphotransferase subunits alpha/beta
- stealth protein gnptab
- glcNAc-1-phosphotransferase subunits alpha/beta
- UDP-N-acetylglucosamine-1-phosphotransferase subunits alpha/beta
- N-acetylglucosamine-1-phosphotransferase subunits alpha/beta-like
- n-acetylglucosamine-1-phosphotransferase subunits alpha/beta-like
- GlcNAc phosphotransferase
- UDP-N-acetylglucosamine-lysosomal-enzyme N-acetylglucosamine
- glucosamine (UDP-N-acetyl)-lysosomal-enzyme N-acetylglucosamine phosphotransferase
- stealth protein GNPTAB
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