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GNMT Products

(Glycine N-Methyltransferase (GNMT))

Categories

The protein encoded by this gene is an enzyme that catalyzes the conversion of S-adenosyl-L-methionine (along with glycine) to S-adenosyl-L-homocysteine and sarcosine. The encoded protein is found in the cytoplasm and acts as a homotetramer. Defects in this gene are a cause of GNMT deficiency (hypermethioninemia). [provided by RefSeq, Oct 2008].

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Featured GNMT Categories

GNMT Antibodies

High quality antibodies with extensive validation data.

GNMT ELISA Kits

Reliable ELISA kits for a wide range of species.

GNMT Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended GNMT Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human, Rat
Application WB, ELISA, IF (cc), IF (p), IHC (fro), IHC (p)
Validations
  • (3)
Cat. No. ABIN739680
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application WB, IHC
Validations
  • (3)
Cat. No. ABIN6262025
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application ELISA, IHC, IF
Validations
  • (2)
Cat. No. ABIN7154182
Quantity 100 μg
Datasheet Datasheet

Recommended GNMT ELISA Kits

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6967143
Quantity 96 tests
Datasheet Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6956244
Quantity 96 tests
Datasheet Datasheet
Reactivity Rat
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN4993471
Quantity 96 tests
Datasheet Datasheet

Recommended GNMT Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
  • (1)
Cat. No. ABIN666718
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1355423
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1355425
Quantity 10 μg
Datasheet Datasheet

Latest Publications for our GNMT products

Fling, Doskey, Fader, Nault, Zacharewski: "2,3,7,8-Tetrachlorodibenzo-p-dioxin (TCDD) dysregulates hepatic one carbon metabolism during the progression of steatosis to steatohepatitis with fibrosis in mice." in: Scientific reports, Vol. 10, Issue 1, pp. 14831, (2021) (PubMed).

Kuai, Luo, Qu, Ru, Luo, Ding, Xing, Liu, Sun, Li, Li: "Transcriptomic Analysis of the Mechanisms for Alleviating Psoriatic Dermatitis Using Taodan Granules in an Imiquimod-Induced Psoriasis-like Mouse Model." in: Frontiers in pharmacology, Vol. 12, pp. 632414, (2021) (PubMed).

Wagner, Choi, Panzitt, Mamrosh, Lee, Zaufel, Xiao, Wooton-Kee, Ståhlman, Newgard, Borén, Moore: "Liver receptor homolog-1 is a critical determinant of methyl-pool metabolism." in: Hepatology (Baltimore, Md.), Vol. 63, Issue 1, pp. 95-106, (2016) (PubMed).

Ottaviani, Brooke, OHanlon-Brown, Waxman, Ali, Buluwela: "Characterisation of the androgen regulation of glycine N-methyltransferase in prostate cancer cells." in: Journal of molecular endocrinology, Vol. 51, Issue 3, pp. 301-12, (2013) (PubMed).

DiBello, Dayal, Kaveti, Zhang, Kinter, Lentz, Jacobsen: "The nutrigenetics of hyperhomocysteinemia: quantitative proteomics reveals differences in the methionine cycle enzymes of gene-induced versus diet-induced hyperhomocysteinemia." in: Molecular & cellular proteomics : MCP, Vol. 9, Issue 3, pp. 471-85, (2010) (PubMed).

Augoustides-Savvopoulou, Luka, Karyda, Stabler, Allen, Patsiaoura, Wagner, Mudd: "Glycine N -methyltransferase deficiency: a new patient with a novel mutation." in: Journal of inherited metabolic disease, Vol. 26, Issue 8, pp. 745-59, (2004) (PubMed).

Tseng, Shih, Huang, Wang, Chen, Chang, Yeh, Chen, Buetow: "Genotypic and phenotypic characterization of a putative tumor susceptibility gene, GNMT, in liver cancer." in: Cancer research, Vol. 63, Issue 3, pp. 647-54, (2003) (PubMed).

Luka, Cerone, Phillips, Mudd, Wagner: "Mutations in human glycine N-methyltransferase give insights into its role in methionine metabolism." in: Human genetics, Vol. 110, Issue 1, pp. 68-74, (2002) (PubMed).

Synonyms and alternative names related to GNMT

glycine N-methyltransferase (CpipJ_CPIJ015956), glycine N-methyltransferase (Gnmt), glycine N-methyltransferase (GNMT)

Protein level used designations for GNMT

  • glycine N-methyltransferase
  • glycine N methyl transferase
  • folate-binding protein
  • glycine methyltransferase
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