GNE Products
(Glucosamine (UDP-N-Acetyl)-2-Epimerase/N-Acetylmannosamine Kinase (GNE))
Categories
The protein encoded by this gene is a bifunctional enzyme that initiates and regulates the biosynthesis of N-acetylneuraminic acid (NeuAc), a precursor of sialic acids. It is a rate-limiting enzyme in the sialic acid biosynthetic pathway. Sialic acid modification of cell surface molecules is crucial for their function in many biologic processes, including cell adhesion and signal transduction. Differential sialylation of cell surface molecules is also implicated in the tumorigenicity and metastatic behavior of malignant cells. Mutations in this gene are associated with sialuria, autosomal recessive inclusion body myopathy, and Nonaka myopathy. Alternative splicing of this gene results in transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008].
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Featured GNE Categories
GNE Antibodies
High quality antibodies with extensive validation data.
GNE ELISA Kits
Reliable ELISA kits for a wide range of species.
GNE Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended GNE Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB, IHC
Validations
- (6)
Cat. No.
ABIN6141232
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human, Mouse, Rat
Application
WB, IHC, ELISA, IF, ICC
Validations
- (3)
Cat. No.
ABIN6258893
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, IHC, ELISA
Validations
- (2)
Cat. No.
ABIN7180179
Quantity
100 μL
Datasheet
Datasheet
Recommended GNE ELISA Kits
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Analytical Method
Validations
Cat. No.
ABIN1123852
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Mouse
Analytical Method
Validations
Cat. No.
ABIN1123853
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Rat
Analytical Method
Validations
Cat. No.
ABIN1123854
Quantity
96 tests
Datasheet
Datasheet
Recommended GNE Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1355375
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1355377
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Tobacco (Nicotiana tabacum)
Validations
Cat. No.
ABIN3092772
Quantity
1 mg
Datasheet
Datasheet
Synonyms and alternative names related to GNE
glucosamine (UDP-N-acetyl)-2-epimerase/N-acetylmannosamine kinase (GNE), glucosamine (UDP-N-acetyl)-2-epimerase/N-acetylmannosamine kinase (gne), glucosamine (UDP-N-acetyl)-2-epimerase/N-acetylmannosamine kinase (Gne), 2310066H07Rik, DMRV, GLCNE, GNE, IBM2, MGC145505, NM, UAE1, Uae1, zgc:77657Protein level used designations for GNE
- UDP-N-acetylglucosamine-2-epimerase/N-acetylmannosamine kinase
- bifunctional UDP-N-acetylglucosamine 2-epimerase/N-acetylmannosamine kinase
- glucosamine (UDP-N-acetyl)-2-epimerase/N-acetylmannosamine kinase
- bifunctional UDP-N-acetylglucosamine 2-epimerase/N-acetylmannosamine kinase-like
- N-acylmannosamine kinase
- UDP-GlcNAc-2-epimerase/ManAc kinase
- UDP-N-acetylglucosamine 2-epimerase/N-acetylmannosamine kinase
- UDP-N-acetylglucosamine-2-epimerase/N- acetylmannosamine kinase
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