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GNAQ Products

(Guanine Nucleotide Binding Protein (G Protein), Q Polypeptide (GNAQ))

Categories

This locus encodes a guanine nucleotide-binding protein. The encoded protein, an alpha subunit in the Gq class, couples a seven-transmembrane domain receptor to activation of phospolipase C-beta. Mutations at this locus have been associated with problems in platelet activation and aggregation. A related pseudogene exists on chromosome 2.[provided by RefSeq, Nov 2010].

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Featured GNAQ Categories

GNAQ Antibodies

High quality antibodies with extensive validation data.

GNAQ Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended GNAQ Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human, Mouse, Rat
Application WB, IHC (p)
Validations
  • (1)
  • (6)
Cat. No. ABIN2855848
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, ELISA
Validations
  • (1)
  • (5)
Cat. No. ABIN516106
Quantity 100 μg
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application WB, ELISA, IHC (p), IF (cc), IF (p), IHC (fro)
Validations
  • (4)
Cat. No. ABIN763181
Quantity 100 μL
Datasheet Datasheet

Recommended GNAQ Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
  • (1)
Cat. No. ABIN7123242
Quantity 50 μg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1355347
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1355345
Quantity 10 μg
Datasheet Datasheet

Latest Publications for our GNAQ products

Rushton, Korb, Kummer, Reichart, Fuchs-Baumgartinger, Tichy, Nell: "Protein expression of KIT, BRAF, GNA11, GNAQ and RASSF1 in feline diffuse iris melanomas." in: Veterinary journal (London, England : 1997), Vol. 249, pp. 33-40, (2019) (PubMed).

Sánchez-Fernández, Cabezudo, Caballero, García-Hoz, Tall, Klett, Michnick, Mayor, Ribas: "Protein Kinase C ζ Interacts with a Novel Binding Region of Gαq to Act as a Functional Effector." in: The Journal of biological chemistry, Vol. 291, Issue 18, pp. 9513-25, (2016) (PubMed).

Ngai, Inngjerdingen, Berge, Taskén: "Interplay between the heterotrimeric G-protein subunits Galphaq and Galphai2 sets the threshold for chemotaxis and TCR activation." in: BMC immunology, Vol. 10, pp. 27, (2009) (PubMed).

Dutt, Kjoller, Giel, Hall, Toksoz: "Activated Galphaq family members induce Rho GTPase activation and Rho-dependent actin filament assembly." in: FEBS letters, Vol. 531, Issue 3, pp. 565-9, (2002) (PubMed).

Li, Iyengar: "Calpain as an effector of the Gq signaling pathway for inhibition of Wnt/beta -catenin-regulated cell proliferation." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 99, Issue 20, pp. 13254-9, (2002) (PubMed).

Strathmann, Simon: "G protein diversity: a distinct class of alpha subunits is present in vertebrates and invertebrates." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 87, Issue 23, pp. 9113-7, (1991) (PubMed).

Synonyms and alternative names related to GNAQ

guanine nucleotide binding protein (G protein), q polypeptide (gnaq), G protein subunit alpha q (GNAQ), G protein subunit alpha q (Gnaq), guanine nucleotide binding protein (G protein), q polypeptide S homeolog (gnaq.S), guanine nucleotide binding protein, alpha q polypeptide (Gnaq), 1110005L02Rik, 6230401I02Rik, AA408290, AW060788, CMC1, Dsk1, Dsk10, G-ALPHA-q, g-alpha-q, Galphaq, GAQ, gaq, Gnaq, gnaqb, Gq, GqI, si:ch73-270f14.2, SWS

Protein level used designations for GNAQ

  • Galpha q
  • gnaqa
  • guanine nucleotide-binding protein G(q) subunit alpha
  • guanine nucleotide-binding protein alpha-q
  • G alpha q
  • guanine nucleotide binding protein alpha q subunit
  • guanine nucleotide binding protein, alpha q polypeptide
  • guanine nucleotide regulatory protein G alpha q
  • heterotrimeric guanine nucleotide-binding protein alpha q subunit
  • guanine nucleotide-binding protein G(q) alpha subunit
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