GNAQ Products
(Guanine Nucleotide Binding Protein (G Protein), Q Polypeptide (GNAQ))
Categories
This locus encodes a guanine nucleotide-binding protein. The encoded protein, an alpha subunit in the Gq class, couples a seven-transmembrane domain receptor to activation of phospolipase C-beta. Mutations at this locus have been associated with problems in platelet activation and aggregation. A related pseudogene exists on chromosome 2.[provided by RefSeq, Nov 2010].
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Featured GNAQ Categories
GNAQ Antibodies
High quality antibodies with extensive validation data.
GNAQ Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended GNAQ Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human, Mouse, Rat
Application
WB, IHC (p)
Validations
- (1)
- (6)
Cat. No.
ABIN2855848
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, ELISA
Validations
- (1)
- (5)
Cat. No.
ABIN516106
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human, Mouse, Rat
Application
WB, ELISA, IHC (p), IF (cc), IF (p), IHC (fro)
Validations
- (4)
Cat. No.
ABIN763181
Quantity
100 μL
Datasheet
Datasheet
Recommended GNAQ Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
- (1)
Cat. No.
ABIN7123242
Quantity
50 μg
Datasheet
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1355347
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1355345
Quantity
10 μg
Datasheet
Datasheet
Latest Publications for our GNAQ products
: "Protein expression of KIT, BRAF, GNA11, GNAQ and RASSF1 in feline diffuse iris melanomas." in: Veterinary journal (London, England : 1997), Vol. 249, pp. 33-40, (2019) (PubMed).: "Protein Kinase C ζ Interacts with a Novel Binding Region of Gαq to Act as a Functional Effector." in: The Journal of biological chemistry, Vol. 291, Issue 18, pp. 9513-25, (2016) (PubMed).
: "Interplay between the heterotrimeric G-protein subunits Galphaq and Galphai2 sets the threshold for chemotaxis and TCR activation." in: BMC immunology, Vol. 10, pp. 27, (2009) (PubMed).
: "Activated Galphaq family members induce Rho GTPase activation and Rho-dependent actin filament assembly." in: FEBS letters, Vol. 531, Issue 3, pp. 565-9, (2002) (PubMed).
: "Calpain as an effector of the Gq signaling pathway for inhibition of Wnt/beta -catenin-regulated cell proliferation." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 99, Issue 20, pp. 13254-9, (2002) (PubMed).
: "G protein diversity: a distinct class of alpha subunits is present in vertebrates and invertebrates." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 87, Issue 23, pp. 9113-7, (1991) (PubMed).
Synonyms and alternative names related to GNAQ
guanine nucleotide binding protein (G protein), q polypeptide (gnaq), G protein subunit alpha q (GNAQ), G protein subunit alpha q (Gnaq), guanine nucleotide binding protein (G protein), q polypeptide S homeolog (gnaq.S), guanine nucleotide binding protein, alpha q polypeptide (Gnaq), 1110005L02Rik, 6230401I02Rik, AA408290, AW060788, CMC1, Dsk1, Dsk10, G-ALPHA-q, g-alpha-q, Galphaq, GAQ, gaq, Gnaq, gnaqb, Gq, GqI, si:ch73-270f14.2, SWSProtein level used designations for GNAQ
- Galpha q
- gnaqa
- guanine nucleotide-binding protein G(q) subunit alpha
- guanine nucleotide-binding protein alpha-q
- G alpha q
- guanine nucleotide binding protein alpha q subunit
- guanine nucleotide binding protein, alpha q polypeptide
- guanine nucleotide regulatory protein G alpha q
- heterotrimeric guanine nucleotide-binding protein alpha q subunit
- guanine nucleotide-binding protein G(q) alpha subunit
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