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GMDS Products

(GDP-Mannose 4,6-Dehydratase (GMDS))
GDP-mannose 4,6-dehydratase (GMD\; EC 4.2.1.47) catalyzes the conversion of GDP-mannose to GDP-4-keto-6-deoxymannose, the first step in the synthesis of GDP-fucose from GDP-mannose, using NADP+ as a cofactor. The second and third steps of the pathway are catalyzed by a single enzyme, GDP-keto-6-deoxymannose 3,5-epimerase, 4-reductase, designated FX in humans (MIM 137020).[supplied by OMIM, Aug 2009].

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Featured GMDS Categories

GMDS Antibodies

High quality antibodies with extensive validation data.

GMDS ELISA Kits

Reliable ELISA kits for a wide range of species.

GMDS Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended GMDS Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application ELISA, IHC, IF
Validations
  • (2)
Cat. No. ABIN7153745
Quantity 100 μg
Datasheet Datasheet
Reactivity Human, Mouse
Application ELISA, IHC
Validations
  • (2)
Cat. No. ABIN7247072
Quantity 200 μL
Datasheet Datasheet
Reactivity Human
Application WB
Validations
  • (2)
Cat. No. ABIN950001
Quantity 100 μg
Datasheet Datasheet

Recommended GMDS ELISA Kits

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method
Validations
Cat. No. ABIN1134585
Quantity 96 tests
Datasheet Datasheet
Reactivity Mouse
Analytical Method
Validations
Cat. No. ABIN1134586
Quantity 96 tests
Datasheet Datasheet

Recommended GMDS Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
  • (1)
Cat. No. ABIN7123070
Quantity 50 μg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1355286
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source HEK-293 Cells
Validations
  • (1)
Cat. No. ABIN2722082
Quantity 20 μg
Datasheet Datasheet

Latest Publications for our GMDS products

Wei, Zhang, Qin, Zhu, Qin, Yu, Wang: "GMDS knockdown impairs cell proliferation and survival in human lung adenocarcinoma." in: BMC cancer, Vol. 18, Issue 1, pp. 600, (2018) (PubMed).

Synonyms and alternative names related to GMDS

GDP-mannose 4, 6-dehydratase (Gmds), GDP-mannose 4,6-dehydratase (GMDS), BC031788, C87208, GMD, SDR3E1

Protein level used designations for GMDS

  • GDP-D-mannose dehydratase
  • GDP-mannose 4,6 dehydratase
  • GMD
  • short chain dehydrogenase/reductase family 3E, member 1
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