Glypican 3 Products
(Glypican 3 (GPC3))
Categories
Cell surface heparan sulfate proteoglycans are composed of a membrane-associated protein core substituted with a variable number of heparan sulfate chains. Members of the glypican-related integral membrane proteoglycan family (GRIPS) contain a core protein anchored to the cytoplasmic membrane via a glycosyl phosphatidylinositol linkage. These proteins may play a role in the control of cell division and growth regulation. The protein encoded by this gene can bind to and inhibit the dipeptidyl peptidase activity of CD26, and it can induce apoptosis in certain cell types. Deletion mutations in this gene are associated with Simpson-Golabi-Behmel syndrome, also known as Simpson dysmorphia syndrome. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2009].
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Featured Glypican 3 Categories
Glypican 3 Antibodies
High quality antibodies with extensive validation data.
Glypican 3 ELISA Kits
Reliable ELISA kits for a wide range of species.
Glypican 3 Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended Glypican 3 Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human, Mouse
Application
WB, FACS, IHC, ELISA, ICC
Validations
- (2)
- (7)
Cat. No.
ABIN969523
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Mouse
Application
WB, IHC, ICC, IP
Validations
- (6)
Cat. No.
ABIN7442228
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, FACS, IHC, ELISA
Validations
- (7)
Cat. No.
ABIN7193621
Quantity
100 μL
Datasheet
Datasheet
Recommended Glypican 3 ELISA Kits
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (7)
- (1)
Cat. No.
ABIN6956276
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (4)
- (1)
Cat. No.
ABIN6973977
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Mouse
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6967170
Quantity
96 tests
Datasheet
Datasheet
Recommended Glypican 3 Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
HEK-293 Cells
Validations
- (4)
Cat. No.
ABIN7274774
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Cynomolgus
Source
HEK-293 Cells
Validations
- (3)
Cat. No.
ABIN7274772
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Source
HEK-293 Cells
Validations
- (3)
Cat. No.
ABIN7274775
Quantity
100 μg
Datasheet
Datasheet
Latest Publications for our Glypican 3 products
: "In Vitro Performance of Published Glypican 3-Targeting Peptides TJ12P1 and L5 Indicates Lack of Specificity and Potency." in: Cancer biotherapy & radiopharmaceuticals, (2019) (PubMed).: "Development and in vitro study of a bi-specific magnetic resonance imaging molecular probe for hepatocellular carcinoma." in: World journal of gastroenterology, Vol. 25, Issue 24, pp. 3030-3043, (2019) (PubMed).
: "Elevated plasma glypicans are associated with organ failure in patients with infection." in: Intensive care medicine experimental, Vol. 7, Issue 1, pp. 2, (2019) (PubMed).
: "Glypican-3: A promising biomarker for hepatocellular carcinoma diagnosis and treatment." in: Medicinal research reviews, Vol. 38, Issue 2, pp. 741-767, (2018) (PubMed).
: "Identification of Glypican-3 as a potential metastasis suppressor gene in gastric cancer." in: Oncotarget, Vol. 7, Issue 28, pp. 44406-44416, (2018) (PubMed).
: "Autophagy suppresses proliferation of HepG2 cells via inhibiting glypican-3/wnt/β-catenin signaling." in: OncoTargets and therapy, Vol. 11, pp. 193-200, (2018) (PubMed).
: "High-density single cell mRNA sequencing to characterize circulating tumor cells in hepatocellular carcinoma." in: Scientific reports, Vol. 8, Issue 1, pp. 11570, (2018) (PubMed).
: "Elevated GPC3 level promotes cell proliferation in liver cancer." in: Oncology letters, Vol. 16, Issue 1, pp. 970-976, (2018) (PubMed).
: "Cytotoxic and partial hepatoprotective activity of sodium ascorbate against hepatocellular carcinoma through inhibition of sulfatase-2 in vivo and in vitro." in: Biomedicine & pharmacotherapy, Vol. 103, pp. 362-372, (2018) (PubMed).
: "New tumor suppressor microRNAs target glypican-3 in human liver cancer." in: Oncotarget, Vol. 8, Issue 25, pp. 41211-41226, (2017) (PubMed).
Synonyms and alternative names related to Glypican 3
glypican 3 (gpc3), glypican 3 (GPC3), glypican 3 (Gpc3), dgsx, DGSX, Glypican-3, GPC3, GTR2-2, MXR7, oci-5, OCI-5, sdys, SDYS, sgb, SGB, sgbs, SGBS, sgbs1, SGBS1Protein level used designations for Glypican 3
- glypican 3
- glypican-3-like
- glypican proteoglycan 3
- glypican-3
- heparan sulphate proteoglycan
- intestinal protein OCI-5
- secreted glypican-3
- defective in Simpson-Golabi-Behmel overgrowth syndrome
- proteoglycan GPC3
- Intestinal protein OCI-5
Did you look for something else?
- GLYP
- Glyoxylate Reductase/hydroxypyruvate Reductase
- Glyoxalase
- GLYCTK
- Glycosyltransferase 25 Domain Containing 1
- Glycosylation Dependent Cell Adhesion Molecule 1 (Pseudogene)
- Glycosylated Serum Protein
- Glycoprotein Xg
- Glycoprotein M6B
- Glycoprotein M6A
- Glycoprotein I
- Glycoprotein G2 (SFTS Virus HN6)
- Glycophosphatidylinositol (GPI)
- Glycolate oxidase 1
- Glycogenin 2
- Glycogenin 1
- Glycogen Synthase Kinase 3
- Glycogen Synthase Kinase
- Glycogen Synthase 2
- Glycogen Synthase 1
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