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Glutaminase Products

(Glutaminase (GLS))
This gene encodes the K-type mitochondrial glutaminase. The encoded protein is an phosphate-activated amidohydrolase that catalyzes the hydrolysis of glutamine to glutamate and ammonia. This protein is primarily expressed in the brain and kidney plays an essential role in generating energy for metabolism, synthesizing the brain neurotransmitter glutamate and maintaining acid-base balance in the kidney. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Jan 2012].

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Featured Glutaminase Categories

Glutaminase Antibodies

High quality antibodies with extensive validation data.

Glutaminase ELISA Kits

Reliable ELISA kits for a wide range of species.

Glutaminase Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended Glutaminase Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human, Mouse, Rat
Application WB, IF, FACS, IHC (p)
Validations
  • (1)
  • (7)
Cat. No. ABIN652757
Quantity 200 μL
Datasheet Datasheet
Reactivity Mouse
Application WB, IHC, IP, ICC
Validations
  • (6)
Cat. No. ABIN7436600
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, ELISA, IF
Validations
  • (4)
  • (4)
Cat. No. ABIN561056
Quantity 100 μg
Datasheet Datasheet

Recommended Glutaminase ELISA Kits

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
  • (1)
Cat. No. ABIN6956181
Quantity 96 tests
Datasheet Datasheet
Reactivity Rat
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
  • (1)
Cat. No. ABIN6956183
Quantity 96 tests
Datasheet Datasheet
Reactivity Mouse
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6956182
Quantity 96 tests
Datasheet Datasheet

Recommended Glutaminase Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
  • (1)
Cat. No. ABIN7123119
Quantity 50 μg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1355244
Quantity 10 μg
Datasheet Datasheet
Reactivity Rat
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN7409218
Quantity 100 μg
Datasheet Datasheet

Latest Publications for our Glutaminase products

Shah, Singh, Eddy, Filipp, Chen: "Concurrent Targeting of Glutaminolysis and Metabotropic Glutamate Receptor 1 (GRM1) Reduces Glutamate Bioavailability in GRM1+ Melanoma." in: Cancer research, Vol. 79, Issue 8, pp. 1799-1809, (2019) (PubMed).

Uddin, Mahmood, Ibrahim, Briski: "Sex-Dimorphic Estrogen Receptor Regulation of Ventromedial Hypothalamic Nucleus Glucoregulatory Neuron Adrenergic Receptor Expression in Hypoglycemic Male and Female Rats." in: Brain research, pp. 146311, (2019) (PubMed).

Wang, Guo, Li, Yu, Han, Liu, Han: "The role of intestinal endotoxemia in a rat model of aluminum neurotoxicity." in: Molecular medicine reports, Vol. 16, Issue 2, pp. 1878-1884, (2018) (PubMed).

Dorai, Shah, Summers, Mathew, Huang, Hsieh, Wu: "NRH:quinone oxidoreductase 2 (NQO2) and glutaminase (GLS) both play a role in large extracellular vesicles (LEV) formation in preclinical LNCaP-C4-2B prostate cancer model of progressive metastasis." in: The Prostate, Vol. 78, Issue 15, pp. 1181-1195, (2018) (PubMed).

Pacheco-Velázquez, Robledo-Cadena, Hernández-Reséndiz, Gallardo-Pérez, Moreno-Sánchez, Rodríguez-Enríquez: "Energy Metabolism Drugs Block Triple Negative Breast Metastatic Cancer Cell Phenotype." in: Molecular pharmaceutics, Vol. 15, Issue 6, pp. 2151-2164, (2018) (PubMed).

Al-Suwailem, Abdi, El-Ansary: "Sex differences in the glutamate signaling pathway in juvenile rats." in: Journal of neuroscience research, Vol. 96, Issue 3, pp. 459-466, (2018) (PubMed).

Wise, Taylor, Herane-Vives, Gammazza, Cappello, Lythgoe, Williams, Young, Cleare, Arnone: "Glutamatergic hypofunction in medication-free major depression: Secondary effects of affective diagnosis and relationship to peripheral glutaminase." in: Journal of affective disorders, Vol. 234, pp. 214-219, (2018) (PubMed).

Lukey, Greene, Erickson, Wilson, Cerione: "The oncogenic transcription factor c-Jun regulates glutaminase expression and sensitizes cells to glutaminase-targeted therapy." in: Nature communications, Vol. 7, pp. 11321, (2016) (PubMed).

Tanaka, Sasayama, Irino, Takata, Nagashima, Satoh, Kyotani, Mizowaki, Imahori, Ejima, Masui, Gini, Yang, Hosoda, Sasaki, Mischel, Kohmura: "Compensatory glutamine metabolism promotes glioblastoma resistance to mTOR inhibitor treatment." in: The Journal of clinical investigation, Vol. 125, Issue 4, pp. 1591-602, (2015) (PubMed).

Reynolds, Lane, Robertson, Kemp, Liu, Hill, Dean, Clem: "Control of glutamine metabolism by the tumor suppressor Rb." in: Oncogene, Vol. 33, Issue 5, pp. 556-66, (2014) (PubMed).

Synonyms and alternative names related to Glutaminase

glutaminase (Gls), glutaminase (GLS), glutaminase (gls), glutaminase b (glsb), Glutaminase (GLS), glutaminase (glsA2), glutaminase (glsA-2), glutaminase (Arnit_3113), glutaminase (Celal_2913), Glutaminase (Celly_0289), glutaminase (Weevi_2101), glutaminase (Mesop_4683), glutaminase kidney isoform, mitochondrial (LOC100069617), 6330442B14, AAD20, AI314027, B230365M23Rik, BA3155, CG8772, CG8872, Dmel\\CG42708, Dmel_CG8772, GA, GAC, GAM, gls, GLS1, Glut, KGA, PAG, RATGLUT, si:dz87i4.2, wu:fa97e05

Protein level used designations for Glutaminase

  • K-glutaminase
  • L-glutamine amidohydrolase
  • glutaminase kidney isoform, mitochondrial
  • glutaminase C
  • glutaminase
  • phosphate-activated glutaminase
  • glutaminase, phosphate-activated
  • CG42708-PA
  • CG42708-PB
  • CG42708-PC
  • CG42708-PD
  • CG42708-PE
  • CG42708-PF
  • CG42708-PH
  • CG42708-PI
  • Glutaminase
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