GLI3 Products
(GLI Family Zinc Finger 3 (GLI3))
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This gene encodes a protein which belongs to the C2H2-type zinc finger proteins subclass of the Gli family. They are characterized as DNA-binding transcription factors and are mediators of Sonic hedgehog (Shh) signaling. The protein encoded by this gene localizes in the cytoplasm and activates patched Drosophila homolog (PTCH) gene expression. It is also thought to play a role during embryogenesis. Mutations in this gene have been associated with several diseases, including Greig cephalopolysyndactyly syndrome, Pallister-Hall syndrome, preaxial polydactyly type IV, and postaxial polydactyly types A1 and B. [provided by RefSeq, Jul 2008].
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Featured GLI3 Categories
GLI3 Antibodies
High quality antibodies with extensive validation data.
GLI3 ELISA Kits
Reliable ELISA kits for a wide range of species.
GLI3 Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended GLI3 Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB, IF, IHC (p), ICC
Validations
- (8)
- (1)
Cat. No.
ABIN2855813
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, ELISA, IHC
Validations
- (1)
- (3)
Cat. No.
ABIN129623
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Application
WB, ELISA, IF, PLA
Validations
- (4)
Cat. No.
ABIN561053
Quantity
100 μg
Datasheet
Datasheet
Recommended GLI3 ELISA Kits
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
Cat. No.
ABIN4883079
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Human
Analytical Method
Semi-Quantitative Sandwich ELISA
Validations
Cat. No.
ABIN6385958
Quantity
96 tests
Datasheet
Datasheet
Recommended GLI3 Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1355197
Quantity
10 μg
Datasheet
Datasheet
Latest Publications for our GLI3 products
: "Sonic hedgehog regulation of human rhabdosphincter muscle:Potential implications for treatment of stress urinary incontinence." in: Neurourology and urodynamics, Vol. 37, Issue 8, pp. 2551-2559, (2019) (PubMed).: "Modulation of the IL-6 Receptor α Underlies GLI2-Mediated Regulation of Ig Secretion in Waldenström Macroglobulinemia Cells." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 195, Issue 6, pp. 2908-16, (2015) (PubMed).
: "Anti-apoptotic role of sonic hedgehog on blood platelets." in: Thrombosis research, Vol. 134, Issue 6, pp. 1311-5, (2014) (PubMed).
: "Anti-apoptotic role of the sonic hedgehog signaling pathway in the proliferation of ameloblastoma." in: International journal of oncology, Vol. 43, Issue 3, pp. 695-702, (2013) (PubMed).
: "Gli2 and Gli3 localize to cilia and require the intraflagellar transport protein polaris for processing and function." in: PLoS genetics, Vol. 1, Issue 4, pp. e53, (2005) (PubMed).
Synonyms and alternative names related to GLI3
GLI family zinc finger 3 (GLI3), GLI family zinc finger 3 (Gli3), GLI family zinc finger 3 L homeolog (gli3.L), GLI-Kruppel family member GLI3 (Gli3), GLI family zinc finger 3 (gli3), ACLS, add, AI854843, AU023367, Bph, GCPS, GLI3, GLI3-190, GLI3FL, im:7142603, PAP-A, PAPA, PAPA1, PAPB, Pdn, PHS, PPDIV, xgli3, XtProtein level used designations for GLI3
- GLI-Kruppel family member GLI3
- glioma-associated oncogene family zinc finger 3
- oncogene GLI3
- transcriptional activator GLI3
- zinc finger protein GLI3
- GLI-Kruppel family member GLI3 (Greig cephalopolysyndactyly syndrome)
- GLI3 full length protein
- neural specific DNA binding protein
- neural-specific DNA-binding protein xGLI3
- xGLI-3
- GLI-Kruppel family member 3
- GLI3 form of 190 kDa
- anterior digit pattern deformity
- brachyphalangy
- extra toes
- polydactyly Nagoya
- zinc finger transcription factor Gli3
- GLI family zinc finger 3
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