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GLI1 Products

(Zinc Finger Protein GLI1 (GLI1))

Categories

This gene encodes a member of the Kruppel family of zinc finger proteins. The encoded transcription factor is activated by the sonic hedgehog signal transduction cascade and regulates stem cell proliferation. The activity and nuclear localization of this protein is negatively regulated by p53 in an inhibitory loop. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2009].

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Featured GLI1 Categories

GLI1 Antibodies

High quality antibodies with extensive validation data.

GLI1 ELISA Kits

Reliable ELISA kits for a wide range of species.

GLI1 Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended GLI1 Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human, Mouse, Pig, Rat
Application WB, ELISA, FACS, IF (cc), IHC (p), IF (p), ICC, IHC (fro)
Validations
  • (8)
  • (5)
Cat. No. ABIN673374
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application ELISA, IHC, FACS, ICC
Validations
  • (7)
Cat. No. ABIN5542320
Quantity 100 μL
Datasheet Datasheet
Reactivity Cow, Dog, Guinea Pig, Horse, Human, Mouse, Rabbit, Rat
Application WB
Validations
  • (8)
  • (5)
Cat. No. ABIN2779593
Quantity 100 μL
Datasheet Datasheet

Recommended GLI1 ELISA Kits

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Rat
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6971225
Quantity 96 tests
Datasheet Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6960589
Quantity 96 tests
Datasheet Datasheet
Reactivity Mouse
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6960590
Quantity 96 tests
Datasheet Datasheet

Recommended GLI1 Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1355193
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1355195
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN7409449
Quantity 100 μg
Datasheet Datasheet

Latest Publications for our GLI1 products

Maghmomeh, El-Gayar, El-Karef, Abdel-Rahman: "Arsenic trioxide and curcumin attenuate cisplatin-induced renal fibrosis in rats through targeting Hedgehog signaling." in: Naunyn-Schmiedeberg's archives of pharmacology, Vol. 393, Issue 3, pp. 303-313, (2021) (PubMed).

Abdel-Rahman, Sharawy, Megahed, El-Awady: "Vitamin D3 abates BDL-induced cholestasis and fibrosis in rats via regulating Hedgehog pathway." in: Toxicology and applied pharmacology, Vol. 380, pp. 114697, (2020) (PubMed).

Mazzone, Gibbons, Eisenman, Strege, Zheng, DAmato, Ordog, Fernandez-Zapico, Farrugia: "Direct repression of anoctamin 1 (ANO1) gene transcription by Gli proteins." in: FASEB journal : official publication of the Federation of American Societies for Experimental Biology, Vol. 33, Issue 5, pp. 6632-6642, (2019) (PubMed).

Chiang, Tan, Kuonen, Hodgkinson, Chiang, Cho, South, Tang, Chang, Rieger, Oro, Sarin: "Genetic mutations underlying phenotypic plasticity in basosquamous carcinoma." in: The Journal of investigative dermatology, (2019) (PubMed).

Petty, Li, Wang, Dai, Heyman, Hsu, Huang, Yang: "Hedgehog signaling promotes tumor-associated macrophage polarization to suppress intratumoral CD8+ T cell recruitment." in: The Journal of clinical investigation, Vol. 129, Issue 12, pp. 5151-5162, (2019) (PubMed).

Yao, Yu, He, Liu, Li, Liu, Long, Wu: "Primary impact of Gli1 on radioresistance in esophageal cancer." in: Oncology letters, Vol. 18, Issue 5, pp. 4825-4833, (2019) (PubMed).

Tanno, Leonardi, Babini, Giardullo, De Stefano, Pasquali, Saran, Mancuso: "Nanog-driven cell-reprogramming and self-renewal maintenance in Ptch1+/-granule cell precursors after radiation injury." in: Scientific reports, Vol. 7, Issue 1, pp. 14238, (2018) (PubMed).

Wang, Chen, Qian, Cui, Gao, Lou: "Hedgehog/Gli1 signaling pathway regulates MGMT expression and chemoresistance to temozolomide in human glioblastoma." in: Cancer cell international, Vol. 17, pp. 117, (2018) (PubMed).

Jin, Zhu, Cheng, Zhang: "Disulfiram/copper targets stem cell-like ALDH+ population of multiple myeloma by inhibition of ALDH1A1 and Hedgehog pathway." in: Journal of cellular biochemistry, Vol. 119, Issue 8, pp. 6882-6893, (2018) (PubMed).

Gao, Li, Li: "Exendin-4 promotes the osteogenic differentiation of osteoblasts via the Hedgehog/Gli1 signaling pathway." in: American journal of translational research, Vol. 10, Issue 1, pp. 315-324, (2018) (PubMed).

Synonyms and alternative names related to GLI1

GLI family zinc finger 1 (GLI1), GLI family zinc finger 1 (Gli1), GLI family zinc finger 1 S homeolog (gli1.S), GLI family zinc finger 1 (gli1), GLI-Kruppel family member GLI1 (Gli1), AV235269, GLI, Gli, Gli-1, gli1.1, Zfp-5, Zfp5

Protein level used designations for GLI1

  • glioma-associated oncogene 1
  • glioma-associated oncogene homolog 1 (zinc finger protein)
  • oncogene GLI
  • zinc finger protein GLI1
  • GLI-Kruppel family member GLI1
  • GLI family zinc finger 1, gene 1
  • zinc finger DNA binding protein Gli-1
  • detour
  • dtr
  • glioma-associated oncogene homolog
  • zinc finger protein 5
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