GLDC Products
(Glycine Dehydrogenase (GLDC))
Categories
Degradation of glycine is brought about by the glycine cleavage system, which is composed of four mitochondrial protein components: P protein (a pyridoxal phosphate-dependent glycine decarboxylase), H protein (a lipoic acid-containing protein), T protein (a tetrahydrofolate-requiring enzyme), and L protein (a lipoamide dehydrogenase). The protein encoded by this gene is the P protein, which binds to glycine and enables the methylamine group from glycine to be transferred to the T protein. Defects in this gene are a cause of nonketotic hyperglycinemia (NKH).[provided by RefSeq, Jan 2010].
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GLDC Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
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Latest Publications for our GLDC products
: "SHMT2 drives glioma cell survival in ischaemia but imposes a dependence on glycine clearance." in: Nature, Vol. 520, Issue 7547, pp. 363-7, (2015) (PubMed).Synonyms and alternative names related to GLDC
glycine dehydrogenase (decarboxylating) GcvP (gcvP), glycine dehydrogenase (gcvP), glycine dehydrogenase (Tb927.7.1910), glycine cleavage system P-protein (gcvP), glycine decarboxylase (Gldc), glycine decarboxylase (GLDC), glycine dehydrogenase (decarboxylating) (gldc), glycine decarboxylase S homeolog (gldc.S), D030049L12Rik, D19Wsu57e, DDBDRAFT_0219205, DDBDRAFT_0231130, DDB_0219205, DDB_0231130, fb23b05, GCE, GCSP, gldc, HYGN1, PSPTO1276, Tb07.43M14.350, wu:fb23b05, zgc:66198Protein level used designations for GLDC
- glycine dehydrogenase
- glycine cleavage system P protein
- glycine dehydrogenase [decarboxylating], mitochondrial
- glycine cleavage system protein P
- glycine decarboxylase P-protein
- glycine cleavage system protein P)
- glycine decarboxylase
- glycine dehydrogenase (decarboxylating; glycine decarboxylase, glycine cleavage system protein P)
- glycine decarboxylase, glycine cleavage system protein P)
- glycine dehydrogenase (decarboxylating), mitochondrial
- glycine decarboxylase S homeolog
- glycine dehydrogenase (decarboxylating) S homeolog
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