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GLDC Products

(Glycine Dehydrogenase (GLDC))
Degradation of glycine is brought about by the glycine cleavage system, which is composed of four mitochondrial protein components: P protein (a pyridoxal phosphate-dependent glycine decarboxylase), H protein (a lipoic acid-containing protein), T protein (a tetrahydrofolate-requiring enzyme), and L protein (a lipoamide dehydrogenase). The protein encoded by this gene is the P protein, which binds to glycine and enables the methylamine group from glycine to be transferred to the T protein. Defects in this gene are a cause of nonketotic hyperglycinemia (NKH).[provided by RefSeq, Jan 2010].

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Featured GLDC Categories

GLDC Antibodies

High quality antibodies with extensive validation data.

GLDC ELISA Kits

Reliable ELISA kits for a wide range of species.

GLDC Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

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Latest Publications for our GLDC products

Kim, Fiske, Birsoy, Freinkman, Kami, Possemato, Chudnovsky, Pacold, Chen, Cantor, Shelton, Gui, Kwon, Ramkissoon, Ligon, Kang, Snuderl, Vander Heiden, Sabatini: "SHMT2 drives glioma cell survival in ischaemia but imposes a dependence on glycine clearance." in: Nature, Vol. 520, Issue 7547, pp. 363-7, (2015) (PubMed).

Synonyms and alternative names related to GLDC

glycine dehydrogenase (decarboxylating) GcvP (gcvP), glycine dehydrogenase (gcvP), glycine dehydrogenase (Tb927.7.1910), glycine cleavage system P-protein (gcvP), glycine decarboxylase (Gldc), glycine decarboxylase (GLDC), glycine dehydrogenase (decarboxylating) (gldc), glycine decarboxylase S homeolog (gldc.S), D030049L12Rik, D19Wsu57e, DDBDRAFT_0219205, DDBDRAFT_0231130, DDB_0219205, DDB_0231130, fb23b05, GCE, GCSP, gldc, HYGN1, PSPTO1276, Tb07.43M14.350, wu:fb23b05, zgc:66198

Protein level used designations for GLDC

  • glycine dehydrogenase
  • glycine cleavage system P protein
  • glycine dehydrogenase [decarboxylating], mitochondrial
  • glycine cleavage system protein P
  • glycine decarboxylase P-protein
  • glycine cleavage system protein P)
  • glycine decarboxylase
  • glycine dehydrogenase (decarboxylating; glycine decarboxylase, glycine cleavage system protein P)
  • glycine decarboxylase, glycine cleavage system protein P)
  • glycine dehydrogenase (decarboxylating), mitochondrial
  • glycine decarboxylase S homeolog
  • glycine dehydrogenase (decarboxylating) S homeolog
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