GJA8 Products
(Gap Junction Protein, alpha 8, 50kDa (GJA8))
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This gene encodes a transmembrane connexin protein that is necessary for lens growth and maturation of lens fiber cells. The encoded protein is a component of gap junction channels and functions in a calcium and pH-dependent manner. Mutations in this gene have been associated with zonular pulverulent cataracts, nuclear progressive cataracts, and cataract-microcornea syndrome. [provided by RefSeq, Dec 2009].
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Featured GJA8 Categories
GJA8 Antibodies
High quality antibodies with extensive validation data.
GJA8 Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended GJA8 Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
ELISA, WB, IHC, IF
Validations
- (4)
Cat. No.
ABIN7153601
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Application
WB
Validations
- (4)
- (1)
Cat. No.
ABIN1882072
Quantity
400 μL
Datasheet
Datasheet
Reactivity
Human
Application
ELISA, WB
Validations
- (2)
Cat. No.
ABIN1774805
Quantity
100 μg
Datasheet
Datasheet
Recommended GJA8 Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1355133
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1355135
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
HEK-293 Cells
Validations
- (1)
Cat. No.
ABIN2721890
Quantity
20 μg
Datasheet
Datasheet
Latest Publications for our GJA8 products
: "Intramolecular loop/tail interactions are essential for connexin 43-hemichannel activity." in: FASEB journal : official publication of the Federation of American Societies for Experimental Biology, Vol. 24, Issue 11, pp. 4378-95, (2010) (PubMed).: "[A novel GJA8 mutation in a Chinese family with autosomal dominant congenital cataract]." in: Zhonghua yi xue yi chuan xue za zhi = Zhonghua yixue yichuanxue zazhi = Chinese journal of medical genetics, Vol. 25, Issue 1, pp. 59-62, (2008) (PubMed).
: "A missense mutation in the human connexin50 gene (GJA8) underlies autosomal dominant "zonular pulverulent" cataract, on chromosome 1q." in: American journal of human genetics, Vol. 62, Issue 3, pp. 526-32, (1998) (PubMed).
: "The human lens intrinsic membrane protein MP70 (Cx50) gene: clonal analysis and chromosome mapping." in: Current eye research, Vol. 14, Issue 10, pp. 979-81, (1996) (PubMed).
: "The human lens intrinsic membrane protein MP70 (Cx50) gene: clonal analysis and chromosome mapping." in: Current eye research, Vol. 14, Issue 3, pp. 215-21, (1995) (PubMed).
Synonyms and alternative names related to GJA8
gap junction protein, alpha 8 (Gja8), gap junction protein alpha 8 (GJA8), Aey5, CAE, CAE1, Cnx50, CTRCT1, Cx45.6, Cx50, CX50, CZP1, Lop10, MP70Protein level used designations for GJA8
- alpha 8 connexin
- connexin-50
- gap junction alpha-8 protein
- gap junction membrane channel protein alpha 8
- lens fiber protein MP70
- lens opacity 10
- connexin 50
- cell surface glycoprotein
- gap junction membrane channel protein alpha-8
- lens intrinsic membrane protein MP70
- connexin 45.6
- connexin-45.6
- MP38
- MP64
- connexin-49
- cx49
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