GIT2 Products
(G Protein-Coupled Receptor Kinase Interactor 2 (GIT2))
Categories
This gene encodes a member of the GIT protein family, which interact with G protein-coupled receptor kinases and possess ADP-ribosylation factor (ARF) GTPase-activating protein (GAP) activity. GIT proteins traffic between cytoplasmic complexes, focal adhesions, and the cell periphery, and interact with Pak interacting exchange factor beta (PIX) to form large oligomeric complexes that transiently recruit other proteins. GIT proteins regulate cytoskeletal dynamics and participate in receptor internalization and membrane trafficking. This gene has been shown to repress lamellipodial extension and focal adhesion turnover, and is thought to regulate cell motility. This gene undergoes extensive alternative splicing to generate multiple isoforms, but the full-length nature of some of these variants has not been determined. The various isoforms have functional differences, with respect to ARF GAP activity and to G protein-coupled receptor kinase 2 binding. [provided by RefSeq, Sep 2008].
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Featured GIT2 Categories
GIT2 Antibodies
High quality antibodies with extensive validation data.
GIT2 ELISA Kits
Reliable ELISA kits for a wide range of species.
GIT2 Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended GIT2 Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB, ELISA, IF, IHC (p)
Validations
- (5)
Cat. No.
ABIN564230
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Application
WB, ELISA, IF, IP
Validations
- (5)
Cat. No.
ABIN564231
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Application
WB, FACS
Validations
- (4)
Cat. No.
ABIN523246
Quantity
50 μg
Datasheet
Datasheet
Recommended GIT2 ELISA Kits
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human, Mouse, Rat
Analytical Method
Qualitative Cell ELISA
Validations
Cat. No.
ABIN5648198
Quantity
96 tests
Datasheet
Datasheet
Recommended GIT2 Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1355123
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1355125
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Tobacco (Nicotiana tabacum)
Validations
Cat. No.
ABIN3080737
Quantity
1 mg
Datasheet
Datasheet
Latest Publications for our GIT2 products
: "The PAK system links Rho GTPase signaling to thrombin-mediated platelet activation." in: American journal of physiology. Cell physiology, Vol. 305, Issue 5, pp. C519-28, (2013) (PubMed).: "VENNTURE--a novel Venn diagram investigational tool for multiple pharmacological dataset analysis." in: PLoS ONE, Vol. 7, Issue 5, pp. e36911, (2012) (PubMed).
: "GIT2 acts as a potential keystone protein in functional hypothalamic networks associated with age-related phenotypic changes in rats." in: PLoS ONE, Vol. 7, Issue 5, pp. e36975, (2012) (PubMed).
: "Minimal peroxide exposure of neuronal cells induces multifaceted adaptive responses." in: PLoS ONE, Vol. 5, Issue 12, pp. e14352, (2010) (PubMed).
Synonyms and alternative names related to GIT2
GIT ArfGAP 2 (GIT2), G protein-coupled receptor kinase interacting ArfGAP 2 (git2), G protein-coupled receptor kinase interacting ArfGAP 2a (git2a), G protein-coupled receptor kinase-interactor 2 (Git2), GIT ArfGAP 2 (Git2), G protein-coupled receptor kinase interacting ArfGAP 2 L homeolog (git2.L), G protein-coupled receptor kinase interacting ArfGAP 2b (git2b), 1500036H07Rik, 5830420E16Rik, 6430510B20Rik, 9630056M03Rik, B230104M05Rik, CAT-2, cat-2, CAT2, git2, mKIAA0148, si:dkey-234h16.4, xgit2, zgc:158416Protein level used designations for GIT2
- ARF GAP GIT2
- ARF GTPase-activating protein GIT2
- G protein-coupled receptor kinase-interactor 2
- GRK-interacting protein 2
- cool-associated, tyrosine phosphorylated protein 2
- cool-interacting tyrosine-phosphorylated protein 2
- G protein-coupled receptor kinase interactor 2
- ARF GTPase activating protein 2
- cool associated tyrosine phosphorylated-2
- G protein-coupled receptor kinase interacting ArfGAP 2 L homeolog
- G protein-coupled receptor kinase interacting ArfGAP 2
- G protein-coupled receptor kinase interactor 2b
- tyrosine-phosphorylated protein CAT-2
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