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GIP Products

(Gastric Inhibitory Polypeptide (GIP))
Preferentially catalyzes the dephosphorylation of 'Ser- 5' within the tandem 7 residues repeats in the C-terminal domain (CTD) of the largest RNA polymerase II subunit POLR2A. Negatively regulates RNA polymerase II transcription, possibly by controlling the transition from initiation/capping to processive transcript elongation (By similarity). Recruited by REST to neuronal genes that contain RE-1 elements, leading to neuronal gene silencing in non-neuronal cells.

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Featured GIP Categories

GIP Antibodies

High quality antibodies with extensive validation data.

GIP ELISA Kits

Reliable ELISA kits for a wide range of species.

GIP Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended GIP Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, IHC, IP, ICC
Validations
  • (3)
Cat. No. ABIN7429760
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, IHC, ELISA
Validations
  • (3)
Cat. No. ABIN7129604
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application IHC, ELISA
Validations
  • (2)
Cat. No. ABIN7139855
Quantity 100 μL
Datasheet Datasheet

Recommended GIP ELISA Kits

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Rat
Analytical Method Quantitative Competition ELISA
Validations
  • (3)
  • (1)
Cat. No. ABIN6956060
Quantity 96 tests
Datasheet Datasheet
Reactivity Rat
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6966966
Quantity 96 tests
Datasheet Datasheet
Reactivity Mouse
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6966965
Quantity 96 tests
Datasheet Datasheet

Recommended GIP Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source HEK-293 Cells
Validations
  • (3)
Cat. No. ABIN7274746
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Source HEK-293 Cells
Validations
  • (3)
Cat. No. ABIN7274747
Quantity 100 μg
Datasheet Datasheet
Reactivity Mouse
Source HEK-293 Cells
Validations
  • (2)
Cat. No. ABIN7274749
Quantity 100 μg
Datasheet Datasheet

Latest Publications for our GIP products

Camacho-Ramírez, Prada-Oliveira, Ribelles-García, Almorza-Gomar, Pérez-Arana: "The Leading Role of Peptide Tyrosine Tyrosine in Glycemic Control After Roux-en-Y Gastric Bypass in Rats." in: Obesity surgery, Vol. 30, Issue 2, pp. 697-706, (2020) (PubMed).

Stafeev, Sklyanik, Yahyaev, Shestakova, Yurasov, Karmadonov, Chibalin, Yu Menshikov, Vorotnikov, Parfyonova, Shestakova: "Low AS160 and high SGK basal phosphorylation associates with impaired incretin profile and type 2 diabetes in adipose tissue of obese patients." in: Diabetes research and clinical practice, Vol. 158, pp. 107928, (2020) (PubMed).

Stygar, Sawczyn, Skrzep-Poloczek, Owczarek, Matysiak, Michalski, Mielańczyk, Bażanów, Ziora, Choręza, Doleżych, Karcz: "The Effects of Duodenojejunal Omega Switch in Combination with High-Fat Diet and Control Diet on Incretins, Body Weight, and Glucose Tolerance in Sprague-Dawley Rats." in: Obesity surgery, Vol. 28, Issue 3, pp. 748-759, (2018) (PubMed).

Skurikhin, Pakhomova, Pershina, Ermolaeva, Krupin, Ermakova, Pan, Kudryashova, Rybalkina, Pavlovskaya, Litvyakov, Goldberg, Dygai: "Regenerative Potential of Spermatogonial Stem Cells, Endothelial Progenitor Cells, and Epithelial Progenitor Cells of C57Bl/6 Male Mice with Metabolic Disorders." in: Bulletin of experimental biology and medicine, Vol. 163, Issue 2, pp. 239-244, (2018) (PubMed).

Zhang, Huang, Li, Chen, Li, Zhou, Wang, Kang, Zhang, Yang, Dong, Wu: "Pancreatic cancer-derived exosomes suppress the production of GIP and GLP-1 from STC-1���cells in vitro by down-regulating the PCSK1/3." in: Cancer letters, Vol. 431, pp. 190-200, (2018) (PubMed).

Dolo, Yao, Li, Zhu, Shi, Widjaja: "Preserving Duodenal-Jejunal (Foregut) Transit Does Not Impair Glucose Tolerance and Diabetes Remission Following Gastric Bypass in Type 2 Diabetes Sprague-Dawley Rat Model." in: Obesity surgery, Vol. 28, Issue 5, pp. 1313-1320, (2018) (PubMed).

Kohashi, Hiromura, Mori, Terasaki, Watanabe, Kushima, Shinmura, Tomoyasu, Nagashima, Hirano: "A Dipeptidyl Peptidase-4 Inhibitor but not Incretins Suppresses Abdominal Aortic Aneurysms in Angiotensin II-Infused Apolipoprotein E-Null Mice." in: Journal of atherosclerosis and thrombosis, Vol. 23, Issue 4, pp. 441-54, (2017) (PubMed).

Tamargo, Bader, Li, Yu, Wang, Talbot, DiMarchi, Pick, Greig: "Novel GLP-1R/GIPR co-agonist "twincretin" is neuroprotective in cell and rodent models of mild traumatic brain injury." in: Experimental neurology, Vol. 288, pp. 176-186, (2017) (PubMed).

Zhang, Li, Li, Zhang, Chen, Liu, Zhang, Zhang, Yang, Hu, Wu, Li, Ju, Yang: "The anti-hyperglycemic efficacy of a lipid-lowering drug Daming capsule and the underlying signaling mechanisms in a rat model of diabetes mellitus." in: Scientific reports, Vol. 6, pp. 34284, (2016) (PubMed).

Banerjee, Zoetewey, Ovee, Mazumder, Petrenko, Samoylova, Mohanty: "Specificity and promiscuity in human glutaminase interacting protein recognition: insight from the binding of the internal and C-terminal motif." in: Biochemistry, Vol. 51, Issue 35, pp. 6950-60, (2012) (PubMed).

Synonyms and alternative names related to GIP

gastric inhibitory polypeptide (GIP), gastric inhibitory polypeptide (gip), gastric inhibitory polypeptide (Gip), gastric inhibitory polypeptide L homeolog (gip.L), GIP, Gludins, RATGLUDINS, xgip

Protein level used designations for GIP

  • glucose-dependent insulinotropic polypeptide
  • gastric inhibitory polypeptide
  • incretin hormone
  • Glucose-dependent insulinotropic peptide
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