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GGA2 Products

(Golgi-Associated, gamma Adaptin Ear Containing, ARF Binding Protein 2 (GGA2))

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This gene encodes a member of the Golgi-localized, gamma adaptin ear-containing, ARF-binding (GGA) family. This family includes ubiquitous coat proteins that regulate the trafficking of proteins between the trans-Golgi network and the lysosome. These proteins share an amino-terminal VHS domain which mediates sorting of the mannose 6-phosphate receptors at the trans-Golgi network. They also contain a carboxy-terminal region with homology to the ear domain of gamma-adaptins. This family member may play a significant role in cargo molecules regulation and clathrin-coated vesicle assembly. [provided by RefSeq, Jul 2008].

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Featured GGA2 Categories

GGA2 Antibodies

High quality antibodies with extensive validation data.

GGA2 Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended GGA2 Antibodies

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Reactivity
Application
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Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, IF
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Cat. No. ABIN3021665
Quantity 100 μL
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Reactivity Human, Mouse
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Cat. No. ABIN7255805
Quantity 200 μL
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Reactivity Human
Application WB, IHC, ELISA
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Cat. No. ABIN7143467
Quantity 100 μL
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Recommended GGA2 ELISA Kits

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
Cat. No. ABIN6217475
Quantity 96 tests
Datasheet Datasheet

Recommended GGA2 Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
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Reactivity Human
Source Wheat germ
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Cat. No. ABIN1355039
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Tobacco (Nicotiana tabacum)
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Cat. No. ABIN3080727
Quantity 1 mg
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Reactivity Mouse
Source Tobacco (Nicotiana tabacum)
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Cat. No. ABIN3123611
Quantity 1 mg
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Latest Publications for our GGA2 products

Kalthoff, Groos, Kohl, Mahrhold, Ungewickell: "Clint: a novel clathrin-binding ENTH-domain protein at the Golgi." in: Molecular biology of the cell, Vol. 13, Issue 11, pp. 4060-73, (2002) (PubMed).

Strausberg, Feingold, Grouse, Derge, Klausner, Collins, Wagner, Shenmen, Schuler, Altschul, Zeeberg, Buetow, Schaefer, Bhat, Hopkins, Jordan, Moore, Max, Wang, Hsieh, Diatchenko, Marusina, Farmer et al.: "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. ..." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 99, Issue 26, pp. 16899-903, (2002) (PubMed).

Nielsen, Madsen, Christensen, Nykjaer, Gliemann, Kasper, Pohlmann, Petersen: "The sortilin cytoplasmic tail conveys Golgi-endosome transport and binds the VHS domain of the GGA2 sorting protein." in: The EMBO journal, Vol. 20, Issue 9, pp. 2180-90, (2001) (PubMed).

Puertollano, Aguilar, Gorshkova, Crouch, Bonifacino: "Sorting of mannose 6-phosphate receptors mediated by the GGAs." in: Science (New York, N.Y.), Vol. 292, Issue 5522, pp. 1712-6, (2001) (PubMed).

Hirst, Lui, Bright, Totty, Seaman, Robinson: "A family of proteins with gamma-adaptin and VHS domains that facilitate trafficking between the trans-Golgi network and the vacuole/lysosome." in: The Journal of cell biology, Vol. 149, Issue 1, pp. 67-80, (2000) (PubMed).

Synonyms and alternative names related to GGA2

golgi associated, gamma adaptin ear containing, ARF binding protein 2 (Gga2), golgi associated, gamma adaptin ear containing, ARF binding protein 2 (GGA2), 1200007E24Rik, mKIAA1080, VEAR

Protein level used designations for GGA2

  • ADP-ribosylation factor-binding protein GGA2
  • gamma-adaptin-related protein 2
  • golgi-localized, gamma ear-containing, ARF-binding protein 2
  • VHS domain and ear domain of gamma-adaptin
  • VHS domain and ear domain-containing protein
  • golgi associated, gamma adaptin ear containing, ARF binding protein 2
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