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GGA1 Products

(Golgi-Associated, gamma Adaptin Ear Containing, ARF Binding Protein 1 (GGA1))

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This gene encodes a member of the Golgi-localized, gamma adaptin ear-containing, ARF-binding (GGA) protein family. Members of this family are ubiquitous coat proteins that regulate the trafficking of proteins between the trans-Golgi network and the lysosome. These proteins share an amino-terminal VHS domain which mediates sorting of the mannose 6-phosphate receptors at the trans-Golgi network. They also contain a carboxy-terminal region with homology to the ear domain of gamma-adaptins. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008].

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Featured GGA1 Categories

GGA1 Antibodies

High quality antibodies with extensive validation data.

GGA1 Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended GGA1 Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, ELISA, IHC (p)
Validations
  • (4)
Cat. No. ABIN565221
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application WB, ELISA, RNAi
Validations
  • (4)
Cat. No. ABIN565222
Quantity 100 μg
Datasheet Datasheet
Reactivity Human, Mouse
Application WB, IF
Validations
  • (1)
  • (2)
Cat. No. ABIN389018
Quantity 400 μL
Datasheet Datasheet

Recommended GGA1 ELISA Kits

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
Cat. No. ABIN6212537
Quantity 96 tests
Datasheet Datasheet

Recommended GGA1 Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1355037
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Tobacco (Nicotiana tabacum)
Validations
Cat. No. ABIN3080754
Quantity 1 mg
Datasheet Datasheet
Reactivity Mouse
Source Tobacco (Nicotiana tabacum)
Validations
Cat. No. ABIN3126561
Quantity 1 mg
Datasheet Datasheet

Latest Publications for our GGA1 products

von Arnim, Spoelgen, Peltan, Deng, Courchesne, Koker, Matsui, Kowa, Lichtenthaler, Irizarry, Hyman: "GGA1 acts as a spatial switch altering amyloid precursor protein trafficking and processing." in: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 26, Issue 39, pp. 9913-22, (2006) (PubMed).

Shiba, Kawasaki, Takatsu, Nogi, Matsugaki, Igarashi, Suzuki, Kato, Nakayama, Wakatsuki: "Molecular mechanism of membrane recruitment of GGA by ARF in lysosomal protein transport." in: Nature structural biology, Vol. 10, Issue 5, pp. 386-93, (2003) (PubMed).

Zhu, Zhai, He, Terzyan, Zhang, Joachimiak, Tang, Zhang: "Crystal structure of the human GGA1 GAT domain." in: Biochemistry, Vol. 42, Issue 21, pp. 6392-9, (2003) (PubMed).

Zhai, He, Liu, Wakeham, Zhu, Li, Tang, Zhang: "The interaction of the human GGA1 GAT domain with rabaptin-5 is mediated by residues on its three-helix bundle." in: Biochemistry, Vol. 42, Issue 47, pp. 13901-8, (2003) (PubMed).

Synonyms and alternative names related to GGA1

putative golgi associated, gamma adaptin ear containing,arf binding protein 1 (gga1) (Smp_164030), golgi associated, gamma adaptin ear containing, ARF binding protein 1 (Gga1), golgi-associated, gamma adaptin ear containing, ARF binding protein 1 (gga1), golgi associated, gamma adaptin ear containing, ARF binding protein 1 (GGA1), 4930406E12Rik, AU016030, AW209092, fb33h10, im:6912200, wu:fb33h10, zgc:101044

Protein level used designations for GGA1

  • golgi associated gamma adaptin ear containing arf binding protein 1 (gga1)
  • ADP-ribosylation factor-binding protein GGA1
  • gamma-adaptin-related protein 1
  • golgi-localized, gamma ear-containing, ARF-binding protein 1
  • ADP-ribosylation factor binding protein 1
  • gamma-adaptin related protein 1
  • golgi associated, gamma adaptin ear containing, ARF binding protein 1
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