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GFRA2 Products

(GDNF Family Receptor alpha 2 (GFRA2))
Glial cell line-derived neurotrophic factor (GDNF) and neurturin (NTN) are two structurally related, potent neurotrophic factors that play key roles in the control of neuron survival and differentiation. The protein encoded by this gene is a member of the GDNF receptor family. It is a glycosylphosphatidylinositol(GPI)-linked cell surface receptor for both GDNF and NTN, and mediates activation of the RET tyrosine kinase receptor. This encoded protein acts preferentially as a receptor for NTN compared to its other family member, GDNF family receptor alpha 1. This gene is a candidate gene for RET-associated diseases. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2009].

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Featured GFRA2 Categories

GFRA2 Antibodies

High quality antibodies with extensive validation data.

GFRA2 ELISA Kits

Reliable ELISA kits for a wide range of species.

GFRA2 Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended GFRA2 Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human, Mouse, Rat
Application WB, ELISA, IF (cc), IF (p), IHC (fro), IHC (p)
Validations
  • (3)
Cat. No. ABIN724235
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, ELISA, IF
Validations
  • (1)
  • (2)
Cat. No. ABIN1450225
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application WB, ELISA, IF
Validations
  • (2)
Cat. No. ABIN7153721
Quantity 100 μg
Datasheet Datasheet

Recommended GFRA2 ELISA Kits

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
Cat. No. ABIN4883060
Quantity 96 tests
Datasheet Datasheet
Reactivity Mouse
Analytical Method Quantitative Sandwich ELISA
Validations
Cat. No. ABIN6730173
Quantity 96 tests
Datasheet Datasheet
Reactivity Human
Analytical Method Semi-Quantitative Sandwich ELISA
Validations
Cat. No. ABIN6384541
Quantity 96 tests
Datasheet Datasheet

Recommended GFRA2 Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Human Cells
Validations
Cat. No. ABIN4371205
Quantity 50 μg
Datasheet Datasheet
Reactivity Human
Source Human Cells
Validations
Cat. No. ABIN1096735
Quantity 50 μg
Datasheet Datasheet
Reactivity Human
Source HEK-293 Cells
Validations
Cat. No. ABIN7534248
Quantity 100 μg
Datasheet Datasheet

Latest Publications for our GFRA2 products

Siatra, Vatsellas, Chatzianastasiou, Balafas, Manolakou, Papapetropoulos, Agapaki, Mouchtouri, Ruchaya, Korovesi, Mavroidis, Thanos, Beis, Kokkinopoulos: "Return of the Tbx5; lineage-tracing reveals ventricular cardiomyocyte-like precursors in the injured adult mammalian heart." in: NPJ Regenerative medicine, Vol. 8, Issue 1, pp. 13, (2023) (PubMed).

Lippoldt, Elmes, McCoy, Knowlton, McKemy: "Artemin, a glial cell line-derived neurotrophic factor family member, induces TRPM8-dependent cold pain." in: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 33, Issue 30, pp. 12543-52, (2013) (PubMed).

Synonyms and alternative names related to GFRA2

GDNF family receptor alpha 2 (GFRA2), glial cell line derived neurotrophic factor family receptor alpha 2 (Gfra2), GDNF family receptor alpha 2 (Gfra2), GDNF family receptor alpha 2 (gfra2), GDNF family receptor alpha 2a (gfra2a), GDNFRB, gdnfrb, gfra2, NRTNR-ALPHA, nrtnr-alpha, NTNRA, ntnra, NTNRALPHA, RETL2, Retl2, retl2, TRNR2, trnr2

Protein level used designations for GFRA2

  • GDNF family receptor alpha-2
  • GDNF receptor beta
  • GDNFR-alpha-2
  • GDNFR-beta
  • GFR-alpha 2
  • NTNR-alpha
  • PI-linked cell-surface accessory protein
  • RET ligand 2
  • TGF-beta-related neurotrophic factor receptor 2
  • TRN receptor, GPI-anchored
  • glial cell line derived neurotrophic factor receptor, beta
  • neurturin receptor alpha
  • GDNF receptor alpha-2
  • GFR alpha 2
  • GFR alpha-2
  • GFR-alpha-2
  • NRTNR-alpha
  • CDC42 binding protein kinase alpha (DMPK-like)
  • glial cell line derived neurotrophic factor family receptor alpha 2
  • tyrosine kinase receptor ligand 2
  • GDNF family receptor alpha 2
  • GDNF family receptor alpha-2-like
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