GFRA1 Products
(GDNF Family Receptor alpha 1 (GFRA1))
Categories
Glial cell line-derived neurotrophic factor (GDNF) and neurturin (NTN) are two structurally related, potent neurotrophic factors that play key roles in the control of neuron survival and differentiation. The protein encoded by this gene is a member of the GDNF receptor family. It is a glycosylphosphatidylinositol(GPI)-linked cell surface receptor for both GDNF and NTN, and mediates activation of the RET tyrosine kinase receptor. This gene is a candidate gene for Hirschsprung disease. Multiple alternatively spliced transcript variants have been described for this gene. [provided by RefSeq, Feb 2009].
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Featured GFRA1 Categories
GFRA1 Antibodies
High quality antibodies with extensive validation data.
GFRA1 ELISA Kits
Reliable ELISA kits for a wide range of species.
GFRA1 Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended GFRA1 Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB, IHC, IP, ICC
Validations
- (6)
Cat. No.
ABIN7430060
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, IHC, IF
Validations
- (1)
- (5)
Cat. No.
ABIN6141065
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, ELISA, IHC, IF
Validations
- (3)
Cat. No.
ABIN7153717
Quantity
100 μg
Datasheet
Datasheet
Recommended GFRA1 ELISA Kits
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Rat
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6966987
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6966986
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Pig
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6966988
Quantity
96 tests
Datasheet
Datasheet
Recommended GFRA1 Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
HEK-293 Cells
Validations
- (3)
Cat. No.
ABIN7274741
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1355034
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1778939
Quantity
10 μg
Datasheet
Datasheet
Latest Publications for our GFRA1 products
: "Systematic identification and comparison of expressed profiles of lncRNAs and circRNAs with associated co-expression and ceRNA networks in mouse germline stem cells." in: Oncotarget, Vol. 8, Issue 16, pp. 26573-26590, (2018) (PubMed).: "Lin28a promotes self-renewal and proliferation of dairy goat spermatogonial stem cells (SSCs) through regulation of mTOR and PI3K/AKT." in: Scientific reports, Vol. 6, pp. 38805, (2016) (PubMed).
: "Quantitative analysis of receptor tyrosine kinase-effector coupling at functionally relevant stimulus levels." in: The Journal of biological chemistry, Vol. 290, Issue 16, pp. 10018-36, (2015) (PubMed).
: "Artemin, a glial cell line-derived neurotrophic factor family member, induces TRPM8-dependent cold pain." in: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 33, Issue 30, pp. 12543-52, (2013) (PubMed).
: "Site-specific gene expression and localization of growth factor ligand receptors RET, GFRα1 and GFRα2 in human adult colon." in: Cell and tissue research, Vol. 354, Issue 2, pp. 371-80, (2013) (PubMed).
: "Unilateral labyrinthectomy induced changes on GDNF receptor complex proteins in the rat medial vestibular nuclei." in: Journal of vestibular research : equilibrium & orientation, Vol. 16, Issue 4-5, pp. 171-7, (2007) (PubMed).
: "Gfra1 silencing in mouse spermatogonial stem cells results in their differentiation via the inactivation of RET tyrosine kinase." in: Biology of reproduction, Vol. 77, Issue 4, pp. 723-33, (2007) (PubMed).
: "Nerve growth factor and glial cell line-derived neurotrophic factor restore the cholinergic neuronal phenotype in organotypic brain slices of the basal nucleus of Meynert." in: Neuroscience, Vol. 102, Issue 1, pp. 129-38, (2001) (PubMed).
: "Glial cell line-derived neurotrophic factor (GDNF) and its receptor (GFR-alpha 1) are strongly expressed in human gliomas." in: Acta neuropathologica, Vol. 99, Issue 2, pp. 131-7, (2000) (PubMed).
: "Caspases: the executioners of apoptosis." in: The Biochemical journal, Vol. 326 ( Pt 1), Issue 5693, pp. 1-16, (1997) (PubMed).
Synonyms and alternative names related to GFRA1
GDNF family receptor alpha 1 (gfra1), GDNF family receptor alpha 1 (GFRA1), glial cell line derived neurotrophic factor family receptor alpha 1 (Gfra1), GDNF family receptor alpha 1 (Gfra1), gdnf family receptor alpha 1a (gfra1a), AU042498, gdnfr, GDNFR, gdnfra, GDNFRA, GDNFRALPHA, gfr-alpha-1, GFR-ALPHA-1, GFRA1, gfralpha1a, MGC122616, ret1l, RET1L, retl1, RETL1, trnr1, TRNR1, zgc:110129Protein level used designations for GFRA1
- GDNF family receptor alpha 1
- GDNF family receptor alpha-1
- GDNF receptor alpha-1
- GDNFR-alpha-1
- GPI-linked anchor protein
- Glial cell line-derived neurotrophic factor receptor alpha
- PI-linked cell-surface accessory protein
- RET ligand 1
- TGF-beta related neurotrophic factor receptor 1
- TGF-beta-related neurotrophic factor receptor 1
- GDNF receptor alpha
- GFR-alpha-1
- GDNF family receptor alpha-1-like
- GDNFR-alpha
- GFR alpha-1
- glial cell line derived neurotrophic factor family receptor alpha 1
- gdnf family receptor alpha 1a
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