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GFR Products

(Rap Guanine Nucleotide Exchange Factor (GEF) 5 (RAPGEF5))

Categories

Members of the RAS (see HRAS\; MIM 190020) subfamily of GTPases function in signal transduction as GTP/GDP-regulated switches that cycle between inactive GDP- and active GTP-bound states. Guanine nucleotide exchange factors (GEFs), such as RAPGEF5, serve as RAS activators by promoting acquisition of GTP to maintain the active GTP-bound state and are the key link between cell surface receptors and RAS activation (Rebhun et al., 2000 [PubMed 10934204]).[supplied by OMIM, Mar 2008].

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Featured GFR Categories

GFR Antibodies

High quality antibodies with extensive validation data.

GFR Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended GFR Antibodies

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Recommended GFR ELISA Kits

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Recommended GFR Proteins

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Synonyms and alternative names related to GFR

Rap guanine nucleotide exchange factor 5 (RAPGEF5), Rap guanine nucleotide exchange factor (GEF) 5 (Rapgef5), Rap guanine nucleotide exchange factor 5 (Rapgef5), Rap guanine nucleotide exchange factor 5 S homeolog (rapgef5.S), 4932413M22, C86120, D030051B22Rik, GFR, MGC154311, mKIAA0277, mmr-gef, MR-GEF, Mrgef, REPAC, RGD1562891, rMR-GEF

Protein level used designations for GFR

  • M-Ras-regulated GEF
  • M-Ras-regulated Rap GEF
  • guanine nucleotide exchange factor for Rap1
  • rap guanine nucleotide exchange factor 5
  • related to Epac
  • MR-GEF
  • Mras regulated guanine nucleotide exchange factor
  • guanine nucleotide exchange factor
  • Rap guanine nucleotide exchange factor (GEF) 5
  • rap guanine nucleotide exchange factor 5-like
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