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Gephyrin Products

(Gephyrin (GPHN))

Categories

This gene encodes a neuronal assembly protein that anchors inhibitory neurotransmitter receptors to the postsynaptic cytoskeleton via high affinity binding to a receptor subunit domain and tubulin dimers. In nonneuronal tissues, the encoded protein is also required for molybdenum cofactor biosynthesis. Mutations in this gene may be associated with the neurological condition hyperplexia and also lead to molybdenum cofactor deficiency. Numerous alternatively spliced transcript variants encoding different isoforms have been described\; however, the full-length nature of all transcript variants is not currently known. [provided by RefSeq, Jul 2008].

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Featured Gephyrin Categories

Gephyrin Antibodies

High quality antibodies with extensive validation data.

Gephyrin Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended Gephyrin Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human, Monkey
Application WB, IHC, FACS, IF, IHC (p)
Validations
  • (9)
Cat. No. ABIN1498424
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Monkey, Rat
Application WB, FACS
Validations
  • (4)
Cat. No. ABIN1498431
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse
Application WB, FACS, IHC (p)
Validations
  • (3)
Cat. No. ABIN653742
Quantity 400 μL
Datasheet Datasheet

Recommended Gephyrin ELISA Kits

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
Cat. No. ABIN6224702
Quantity 96 tests
Datasheet Datasheet

Recommended Gephyrin Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1355540
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Tobacco (Nicotiana tabacum)
Validations
Cat. No. ABIN3092743
Quantity 1 mg
Datasheet Datasheet
Reactivity Mouse
Source Tobacco (Nicotiana tabacum)
Validations
Cat. No. ABIN3136278
Quantity 1 mg
Datasheet Datasheet

Latest Publications for our Gephyrin products

Kneussel, Haverkamp, Fuhrmann, Wang, Wässle, Olsen, Betz: "The gamma-aminobutyric acid type A receptor (GABAAR)-associated protein GABARAP interacts with gephyrin but is not involved in receptor anchoring at the synapse." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 97, Issue 15, pp. 8594-9, (2000) (PubMed).

Feng, Tintrup, Kirsch, Nichol, Kuhse, Betz, Sanes: "Dual requirement for gephyrin in glycine receptor clustering and molybdoenzyme activity." in: Science (New York, N.Y.), Vol. 282, Issue 5392, pp. 1321-4, (1998) (PubMed).

Meyer, Kirsch, Betz, Langosch: "Identification of a gephyrin binding motif on the glycine receptor beta subunit." in: Neuron, Vol. 15, Issue 3, pp. 563-72, (1995) (PubMed).

Prior, Schmitt, Grenningloh, Pribilla, Multhaup, Beyreuther, Maulet, Werner, Langosch, Kirsch: "Primary structure and alternative splice variants of gephyrin, a putative glycine receptor-tubulin linker protein." in: Neuron, Vol. 8, Issue 6, pp. 1161-70, (1992) (PubMed).

Synonyms and alternative names related to Gephyrin

gephyrin (Gphn), gephyrin (GPHN), gephyrin L homeolog (gphn.L), gephyrin a (gphna), gephyrin (PTRG_08978), gephyrin (VDBG_00775), gephyrin (Tsp_03043), gephyrin (gphn), 5730552E08Rik, AI662856, BC027112, C230040D23, DKFZp459M0825, geph, Geph, GEPH, gpgb1, GPH, GPHN, GPHRYN, HKPX1

Protein level used designations for Gephyrin

  • gephyrin isoform
  • putative glycine receptor-tubulin linker protein
  • gephyrin
  • gephyrin1
  • gephyrin-like
  • LOW QUALITY PROTEIN: gephyrin
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