GEN1 Products
(Gen Endonuclease Homolog 1 (GEN1))
Categories
Endonuclease which resolves Holliday junctions by the introduction of symmetrically related cuts across the junction point, to produce nicked duplex products in which the nicks can be readily ligated. Four-way DNA intermediates, also known as Holliday junctions, are formed during homologous recombination and DNA repair, and their resolution is necessary for proper chromosome segregation.
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Featured GEN1 Categories
GEN1 Antibodies
High quality antibodies with extensive validation data.
GEN1 Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended GEN1 Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human, Mouse
Application
WB
Validations
- (2)
Cat. No.
ABIN653446
Quantity
400 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB
Validations
- (1)
Cat. No.
ABIN6141058
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, ELISA, IF (cc), IF (p), IHC (fro), IHC (p), ICC
Validations
Cat. No.
ABIN1715019
Quantity
100 μL
Datasheet
Datasheet
Recommended GEN1 Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Tobacco (Nicotiana tabacum)
Validations
Cat. No.
ABIN3092747
Quantity
1 mg
Datasheet
Datasheet
Reactivity
Mouse
Source
Tobacco (Nicotiana tabacum)
Validations
Cat. No.
ABIN3136234
Quantity
1 mg
Datasheet
Datasheet
Reactivity
Staphylococcus aureus
Source
Yeast
Validations
- (1)
Cat. No.
ABIN5713720
Quantity
100 μg
Datasheet
Datasheet
Latest Publications for our GEN1 products
: "SLX4 Prevents GEN1-Dependent DSBs During DNA Replication Arrest Under Pathological Conditions in Human Cells." in: Scientific reports, Vol. 7, pp. 44464, (2018) (PubMed).: "Identification of Holliday junction resolvases from humans and yeast." in: Nature, Vol. 456, Issue 7220, pp. 357-61, (2008) (PubMed).
Synonyms and alternative names related to GEN1
GEN1, Holliday junction 5' flap endonuclease (GEN1), GEN1, Holliday junction 5' flap endonuclease (Gen1), GEN1 Holliday junction 5' flap endonuclease (Gen1), 5830483C08Rik, Gen, RGD1559792Protein level used designations for GEN1
- Gen homolog 1, endonuclease
- flap endonuclease GEN homolog 1
- Gen endonuclease homolog 1
- Holliday junction resolvase
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