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GDF15 Products

(Growth Differentiation Factor 15 (GDF15))

Categories

Bone morphogenetic proteins (e.g., BMP9\; MIM 605120) are members of the transforming growth factor-beta (see TGFB1\; MIM 190180) superfamily and regulate tissue differentiation and maintenance. They are synthesized as precursor molecules that are processed at a dibasic cleavage site to release C-terminal domains containing a characteristic motif of 7 conserved cysteines in the mature protein.[supplied by OMIM, Oct 2009].

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Featured GDF15 Categories

GDF15 Antibodies

High quality antibodies with extensive validation data.

GDF15 ELISA Kits

Reliable ELISA kits for a wide range of species.

GDF15 Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended GDF15 Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, IHC, IP, IF
Validations
  • (3)
  • (6)
Cat. No. ABIN3020659
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, ELISA, IHC, FACS
Validations
  • (10)
Cat. No. ABIN185465
Quantity 100 μg
Datasheet Datasheet
Reactivity Human, Mouse
Application WB, ELISA
Validations
  • (1)
  • (3)
Cat. No. ABIN1043920
Quantity 100 μg
Datasheet Datasheet

Recommended GDF15 ELISA Kits

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
  • (1)
Cat. No. ABIN6956321
Quantity 96 tests
Datasheet Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
  • (1)
Cat. No. ABIN6976099
Quantity 96 tests
Datasheet Datasheet
Reactivity Rat
Analytical Method Quantitative Competition ELISA
Validations
  • (1)
Cat. No. ABIN6974344
Quantity 96 tests
Datasheet Datasheet

Recommended GDF15 Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
  • (5)
Cat. No. ABIN7274723
Quantity 100 μg
Datasheet Datasheet
Reactivity Cynomolgus
Source HEK-293 Cells
Validations
  • (4)
Cat. No. ABIN7274719
Quantity 100 μg
Datasheet Datasheet
Reactivity Mouse
Source HEK-293 Cells
Validations
  • (4)
Cat. No. ABIN7274729
Quantity 100 μg
Datasheet Datasheet

Latest Publications for our GDF15 products

Huang, Wang, Lo, Tseng, Chen, Wu, Hou, Yuan: "Visfatin Mediates Malignant Behaviors through Adipose-Derived Stem Cells Intermediary in Breast Cancer." in: Cancers, Vol. 12, Issue 1, (2019) (PubMed).

Uysal, Arslan, Buyukinan, Gederet, Vatansev, Ozcelik: "Growth Differentiation Factor-15 Level and Tissue Doppler Echocardiography as a Tool in Identification of Cardiac Effects in the Children with Type 1 Diabetes Mellitus." in: Experimental and clinical endocrinology & diabetes : official journal, German Society of Endocrinology [and] German Diabetes Association, (2019) (PubMed).

Wang, Yang, Dai, Lu, Zhang, Keller: "Prostate cancer promotes a vicious cycle of bone metastasis progression through inducing osteocytes to secrete GDF15 that stimulates prostate cancer growth and invasion." in: Oncogene, Vol. 38, Issue 23, pp. 4540-4559, (2019) (PubMed).

Li, Cui, Huang, Li, Jia, Liu, Qi: "Additional Diagnostic Value of Growth Differentiation Factor-15 (GDF-15) to N-Terminal B-Type Natriuretic Peptide (NT-proBNP) in Patients with Different Stages of Heart Failure." in: Medical science monitor : international medical journal of experimental and clinical research, Vol. 24, pp. 4992-4999, (2018) (PubMed).

Falk, Huhn, Behmenburg, Ritz-Timme, Mayer: "Biomechanical stress in myocardial infarctions: can endothelin-1 and growth differentiation factor 15 serve as immunohistochemical markers?" in: International journal of legal medicine, Vol. 132, Issue 2, pp. 509-518, (2017) (PubMed).

Han, Dai, Yousafzai, Wang, Wang, Zhou, Lu, Xu, Feng, Jin, Wang: "CXXC4 activates apoptosis through up-regulating GDF15 in gastric cancer." in: Oncotarget, Vol. 8, Issue 61, pp. 103557-103567, (2017) (PubMed).

Ilhan, Bilgin, Toylu, Dogan, Apaydin: "The Expression of GDF-15 in the Human Vitreous in the Presence of Retinal Pathologies with an Inflammatory Component." in: Ocular immunology and inflammation, Vol. 24, Issue 2, pp. 178-83, (2016) (PubMed).

Wu, Ding, Han, Arriens, Wei, Han, Pedroza, Jiang, Anolik, Petri, Sanz, Saxena, Mohan: "Antibody-Array-Based Proteomic Screening of Serum Markers in Systemic Lupus Erythematosus: A Discovery Study." in: Journal of proteome research, Vol. 15, Issue 7, pp. 2102-14, (2016) (PubMed).

Ueno, Samura, Nakamura, Tanaka, Takeuchi, Kawamura, Takahashi, Hosoyama, Morikage, Hamano: "Increased plasma VEGF levels following ischemic preconditioning are associated with downregulation of miRNA-762 and miR-3072-5p." in: Scientific reports, Vol. 6, pp. 36758, (2016) (PubMed).

Tsui, Hsu, Chung, Lin, Feng, Lee, Chang, Juang: "Growth differentiation factor-15: a p53- and demethylation-upregulating gene represses cell proliferation, invasion, and tumorigenesis in bladder carcinoma cells." in: Scientific reports, Vol. 5, pp. 12870, (2016) (PubMed).

Synonyms and alternative names related to GDF15

growth differentiation factor 15 (GDF15), growth differentiation factor 15 (Gdf15), GDF-15, GDF15, MIC-1, MIC1, NAG-1, PDF, PLAB, PTGFB, SBF

Protein level used designations for GDF15

  • growth differentiation factor 15
  • NRG-1
  • NSAID (nonsteroidal anti-inflammatory drug)-activated protein 1
  • NSAID-activated gene 1 protein
  • NSAID-regulated gene 1 protein
  • PTGF-beta
  • growth/differentiation factor 15
  • macrophage inhibitory cytokine 1
  • placental TGF-beta
  • placental bone morphogenetic protein
  • prostate differentiation factor
  • GDF-15
  • macrophage inhibiting cytokine-1
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