GCS1 Products
(Mannosyl-Oligosaccharide Glucosidase (MOGS))
Categories
This gene encodes the first enzyme in the N-linked oligosaccharide processing pathway. The enzyme cleaves the distal alpha-1,2-linked glucose residue from the Glc(3)-Man(9)-GlcNAc(2) oligosaccharide precursor. This protein is located in the lumen of the endoplasmic reticulum. Defects in this gene are a cause of type IIb congenital disorder of glycosylation (CDGIIb). Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2009].
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Featured GCS1 Categories
GCS1 Antibodies
High quality antibodies with extensive validation data.
GCS1 Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended GCS1 Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB
Validations
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Cat. No.
ABIN389016
Quantity
400 μL
Datasheet
Datasheet
Reactivity
Human, Mouse
Application
WB
Validations
- (1)
Cat. No.
ABIN389017
Quantity
400 μL
Datasheet
Datasheet
Reactivity
Human, Mouse, Rat
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Validations
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Cat. No.
ABIN7256322
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Datasheet
Datasheet
Recommended GCS1 Proteins
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Reactivity
Source
Validations
Cat. No.
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Datasheet
Reactivity
Human
Source
Escherichia coli (E. coli)
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Cat. No.
ABIN7419994
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Mouse
Source
Escherichia coli (E. coli)
Validations
Cat. No.
ABIN7419997
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Source
Tobacco (Nicotiana tabacum)
Validations
Cat. No.
ABIN3114747
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Datasheet
Datasheet
Latest Publications for our GCS1 products
: "p32 regulates ER stress and lipid homeostasis by down-regulating GCS1 expression." in: FASEB journal : official publication of the Federation of American Societies for Experimental Biology, Vol. 32, Issue 7, pp. 3892-3902, (2019) (PubMed).: "Processing of N-linked carbohydrate chains in a patient with glucosidase I deficiency (CDG type IIb)." in: Glycobiology, Vol. 12, Issue 8, pp. 473-83, (2002) (PubMed).
: "A novel disorder caused by defective biosynthesis of N-linked oligosaccharides due to glucosidase I deficiency." in: American journal of human genetics, Vol. 66, Issue 6, pp. 1744-56, (2001) (PubMed).
Synonyms and alternative names related to GCS1
mannosyl-oligosaccharide glucosidase (AFUA_6G04210), mannosyl-oligosaccharide glucosidase (Tc00.1047053511015.10), mannosyl-oligosaccharide glucosidase (Tc00.1047053511805.10), mannosyl-oligosaccharide glucosidase GCS1 (LOC5576381), mannosyl-oligosaccharide glucosidase (AOR_1_260114), mannosyl-oligosaccharide glucosidase (MGYG_00305), mannosyl-oligosaccharide glucosidase (TERG_01248), mannosyl-oligosaccharide glucosidase L homeolog (mogs.L), mannosyl oligosaccharide glucosidase (TTHERM_00636930), mannosyl oligosaccharide glucosidase (LOAG_03690), glucosidase 1 (Gcs1), mannosyl-oligosaccharide glucosidase (MOGS), mannosyl-oligosaccharide glucosidase (Mogs), mannosyl-oligosaccharide glucosidase (mogs), 1810017N02Rik, Afu6g04210, AI181835, AO090701000141, CDG2B, CWH41, DER7, GCS1, Gcs1, gcs1, im:7160827, Mogs, wu:fe50a12, wu:fk09a10, zgc:158312Protein level used designations for GCS1
- mannosyl-oligosaccharide glucosidase
- Mannosyl oligosaccharide glucosidase
- mannosyl oligosaccharide glucosidase
- glycoprotein-processing glucosidase I
- glucosidase I
- processing A-glucosidase I
- glucosidase 1
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