GCG Products
(Glucagon (GCG))
Categories
The protein encoded by this gene is actually a preproprotein that is cleaved into four distinct mature peptides. One of these, glucagon, is a pancreatic hormone that counteracts the glucose-lowering action of insulin by stimulating glycogenolysis and gluconeogenesis. Glucagon is a ligand for a specific G-protein linked receptor whose signalling pathway controls cell proliferation. Two of the other peptides are secreted from gut endocrine cells and promote nutrient absorption through distinct mechanisms. Finally, the fourth peptide is similar to glicentin, an active enteroglucagon. [provided by RefSeq, Jul 2008].
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Featured GCG Categories
GCG Antibodies
High quality antibodies with extensive validation data.
GCG ELISA Kits
Reliable ELISA kits for a wide range of species.
GCG Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended GCG Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
ELISA, WB, IHC, IF, IHC (p)
Validations
- (2)
- (1)
Cat. No.
ABIN7448121
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Application
WB, IF, IHC (p), FACS
Validations
- (6)
Cat. No.
ABIN390769
Quantity
400 μL
Datasheet
Datasheet
Reactivity
Mouse
Application
WB, IHC, IP, ICC
Validations
- (5)
Cat. No.
ABIN7429778
Quantity
100 μL
Datasheet
Datasheet
Recommended GCG ELISA Kits
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Analytical Method
Quantitative Competition ELISA
Validations
- (1)
- (1)
Cat. No.
ABIN6963535
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Human
Analytical Method
Quantitative Competition ELISA
Validations
- (2)
- (1)
Cat. No.
ABIN6956102
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Mouse
Analytical Method
Quantitative Competition ELISA
Validations
- (7)
- (1)
Cat. No.
ABIN6956103
Quantity
96 tests
Datasheet
Datasheet
Recommended GCG Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
- (1)
Cat. No.
ABIN7123099
Quantity
50 μg
Datasheet
Datasheet
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
- (1)
Cat. No.
ABIN7123098
Quantity
50 μg
Datasheet
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1354908
Quantity
10 μg
Datasheet
Datasheet
Latest Publications for our GCG products
: "Effect of fully automated closed-loop insulin delivery using faster aspart versus standard aspart on gluco-regulatory hormones in type 2 diabetes." in: Diabetes, obesity & metabolism, Vol. 23, Issue 1, pp. 228-233, (2021) (PubMed).: "Emodin Alleviates Severe Acute Pancreatitis-Associated Acute Lung Injury by Inhibiting the Cold-Inducible RNA-Binding Protein (CIRP)-Mediated Activation of the NLRP3/IL-1β/CXCL1 Signaling." in: Frontiers in pharmacology, Vol. 12, pp. 655372, (2021) (PubMed).
: "HWL-088, a new potent free fatty acid receptor 1 (FFAR1) agonist, improves glucolipid metabolism and acts additively with metformin in ob/ob diabetic mice." in: British journal of pharmacology, Vol. 177, Issue 10, pp. 2286-2302, (2021) (PubMed).
: "In vitro expansion of pancreatic islet clusters facilitated by hormones and chemicals." in: Cell discovery, Vol. 6, pp. 20, (2020) (PubMed).
: "Identification of Potential Therapeutic Targets and Pathways of Liraglutide Against Type 2 Diabetes Mellitus (T2DM) Based on Long Non-Coding RNA (lncRNA) Sequencing." in: Medical science monitor : international medical journal of experimental and clinical research, Vol. 26, pp. e922210, (2020) (PubMed).
: "Necrostatin-1 supplementation enhances young porcine islet maturation and in vitro function." in: Xenotransplantation, pp. e12555, (2019) (PubMed).
: "Exogenous obestatin decreases beta-cell apoptosis and alfa-cell proliferation in high fat diet and streptozotocin induced type 2 diabetic rats." in: European journal of pharmacology, Vol. 851, pp. 36-42, (2019) (PubMed).
: "Nigella sativa Oil and Chromium Picolinate Ameliorate Fructose-Induced Hyperinsulinemia by Enhancing Insulin Signaling and Suppressing Insulin-Degrading Enzyme in Male Rats." in: Biological trace element research, Vol. 184, Issue 1, pp. 119-126, (2018) (PubMed).
: "6-Shogaol ameliorates diabetic nephropathy through anti-inflammatory, hyperlipidemic, anti-oxidative activity in db/db mice." in: Biomedicine & pharmacotherapy, Vol. 97, pp. 633-641, (2018) (PubMed).
: "Chronic oscillating glucose challenges disarrange innate immune homeostasis to potentiate the variation of neutrophil-lymphocyte ratio in rats with or without hidden diabetes mellitus." in: Diabetes, metabolic syndrome and obesity : targets and therapy, Vol. 11, pp. 277-288, (2018) (PubMed).
Synonyms and alternative names related to GCG
glucagon (GCG), glucagon (Gcg), glucagon L homeolog (gcg.L), GCG, gcg-A, gcg1, GLP-1, GLP1, GLP2, Glu, GRPP, PPGProtein level used designations for GCG
- glicentin-related polypeptide
- glucagon-like peptide 1
- glucagon-like peptide 2
- preproglucagon
- glucagon-like peptide I
- glucagon-like peptide-1
- proglucagon
- glucagon
- preproglucagon B
- glucagon preproprotein
- preproglucagon A
- glucagon I
- glucagon-1
- proglucagon I
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