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GCDH Products

(Glutaryl-CoA Dehydrogenase (GCDH))

Categories

The protein encoded by this gene belongs to the acyl-CoA dehydrogenase family. It catalyzes the oxidative decarboxylation of glutaryl-CoA to crotonyl-CoA and CO(2) in the degradative pathway of L-lysine, L-hydroxylysine, and L-tryptophan metabolism. It uses electron transfer flavoprotein as its electron acceptor. The enzyme exists in the mitochondrial matrix as a homotetramer of 45-kD subunits. Mutations in this gene result in the metabolic disorder glutaric aciduria type 1, which is also known as glutaric acidemia type I. Alternative splicing of this gene results in multiple transcript variants. A related pseudogene has been identified on chromosome 12. [provided by RefSeq, Mar 2013].

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Featured GCDH Categories

GCDH Antibodies

High quality antibodies with extensive validation data.

GCDH ELISA Kits

Reliable ELISA kits for a wide range of species.

GCDH Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended GCDH Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, IHC, IP, ICC
Validations
  • (5)
Cat. No. ABIN7445012
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, IHC, ELISA, IP
Validations
  • (4)
Cat. No. ABIN7154056
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application WB, IF
Validations
  • (4)
Cat. No. ABIN515979
Quantity 50 μg
Datasheet Datasheet

Recommended GCDH ELISA Kits

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method Quantitative Competition ELISA
Validations
Cat. No. ABIN5594801
Quantity 96 tests
Datasheet Datasheet
Reactivity Human
Analytical Method
Validations
Cat. No. ABIN1134990
Quantity 96 tests
Datasheet Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
Cat. No. ABIN6230119
Quantity 96 tests
Datasheet Datasheet

Recommended GCDH Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1354902
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
  • (1)
Cat. No. ABIN7123126
Quantity 50 μg
Datasheet Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN7419541
Quantity 100 μg
Datasheet Datasheet

Latest Publications for our GCDH products

Hu, Lausted, Yoo, Yan, Brightman, Chen, Wang, Bu, Hood: "Quantitative liver-specific protein fingerprint in blood: a signature for hepatotoxicity." in: Theranostics, Vol. 4, Issue 2, pp. 215-28, (2014) (PubMed).

Lazrek, Goffard, Schanen, Karquel, Bocket, Lion, Devaux, Hedouin, Gosset, Hober: "Detection of hepatitis C virus antibodies and RNA among medicolegal autopsy cases in Northern France." in: Diagnostic microbiology and infectious disease, Vol. 55, Issue 1, pp. 55-8, (2006) (PubMed).

Synonyms and alternative names related to GCDH

glutaryl-CoA dehydrogenase (GCDH), glutaryl-CoA dehydrogenase (Gcdh), glutaryl-CoA dehydrogenase a (gcdha), glutaryl-Coenzyme A dehydrogenase (Gcdh), 9030411L18, ACAD5, AI266902, D17825, GCD, zgc:56505, zgc:77704

Protein level used designations for GCDH

  • glutaryl-CoA dehydrogenase, mitochondrial
  • glutaryl-Coenzyme A dehydrogenase
  • GCD
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