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G3BP1 Products

(GTPase Activating Protein (SH3 Domain) Binding Protein 1 (G3BP1))

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This gene encodes one of the DNA-unwinding enzymes which prefers partially unwound 3'-tailed substrates and can also unwind partial RNA/DNA and RNA/RNA duplexes in an ATP-dependent fashion. This enzyme is a member of the heterogeneous nuclear RNA-binding proteins and is also an element of the Ras signal transduction pathway. It binds specifically to the Ras-GTPase-activating protein by associating with its SH3 domain. Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of some of these variants has not been determined. [provided by RefSeq, Jul 2008].

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Featured G3BP1 Categories

G3BP1 Antibodies

High quality antibodies with extensive validation data.

G3BP1 ELISA Kits

Reliable ELISA kits for a wide range of species.

G3BP1 Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended G3BP1 Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, ELISA, IF, IHC (p), RNAi
Validations
  • (4)
  • (7)
Cat. No. ABIN564390
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application WB, IF
Validations
  • (1)
  • (4)
Cat. No. ABIN523522
Quantity 50 μg
Datasheet Datasheet
Reactivity Cow, Dog, Guinea Pig, Horse, Human, Mouse, Rabbit, Rat
Application WB, IHC, IP
Validations
  • (6)
Cat. No. ABIN2780222
Quantity 100 μL
Datasheet Datasheet

Recommended G3BP1 ELISA Kits

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human, Mouse
Analytical Method Qualitative Cell ELISA
Validations
Cat. No. ABIN1380586
Quantity 2 x 96 tests
Datasheet Datasheet
Reactivity Cow
Analytical Method
Validations
Cat. No. ABIN1154507
Quantity 96 tests
Datasheet Datasheet

Recommended G3BP1 Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
  • (1)
Cat. No. ABIN7123226
Quantity 50 μg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1354601
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1354599
Quantity 10 μg
Datasheet Datasheet

Latest Publications for our G3BP1 products

Hu, Wang, Tang, Yang, Qin, Chen: "Inclusion bodies of human parainfluenza virus type 3 inhibit antiviral stress granule formation by shielding viral RNAs." in: PLoS pathogens, Vol. 14, Issue 3, pp. e1006948, (2018) (PubMed).

Ye, Pan, Wang, Fang, Ma, Zhu, Shi, Zhang, Zheng, Chen, Li, Xiao: "Foot-and-Mouth Disease Virus Counteracts on Internal Ribosome Entry Site Suppression by G3BP1 and Inhibits G3BP1-Mediated Stress Granule Assembly via Post-Translational Mechanisms." in: Frontiers in immunology, Vol. 9, pp. 1142, (2018) (PubMed).

Martin, Bellora, González-Vallinas, Irimia, Chebli, de Toledo, Raabe, Eyras, Urlaub, Blencowe, Tazi: "Preferential binding of a stable G3BP ribonucleoprotein complex to intron-retaining transcripts in mouse brain and modulation of their expression in the cerebellum." in: Journal of neurochemistry, Vol. 139, Issue 3, pp. 349-368, (2016) (PubMed).

Lind, Svedin, Domsgen, Kapell, Laitinen, Moll, Flodström-Tullberg: "Coxsackievirus counters the host innate immune response by blocking type III interferon expression." in: The Journal of general virology, Vol. 97, Issue 6, pp. 1-12, (2016) (PubMed).

Schulte, Liu, Panas, Thaa, Dickson, Götte, Achour, McInerney: "Combined structural, biochemical and cellular evidence demonstrates that both FGDF motifs in alphavirus nsP3 are required for efficient replication." in: Open biology, Vol. 6, Issue 7, (2016) (PubMed).

He, Yang, Abdellatif, Sayed: "GTPase Activating Protein (Sh3 Domain) Binding Protein 1 Regulates the Processing of MicroRNA-1 during Cardiac Hypertrophy." in: PLoS ONE, Vol. 10, Issue 12, pp. e0145112, (2015) (PubMed).

Luo, Fang, Jin, Wang, An, Xu, Chen, Xiao: "Label-free quantitative phosphoproteomic analysis reveals differentially regulated proteins and pathway in PRRSV-infected pulmonary alveolar macrophages." in: Journal of proteome research, Vol. 13, Issue 3, pp. 1270-80, (2014) (PubMed).

Kaehler, Isensee, Hucho, Lehrach, Krobitsch: "5-Fluorouracil affects assembly of stress granules based on RNA incorporation." in: Nucleic acids research, Vol. 42, Issue 10, pp. 6436-47, (2014) (PubMed).

Martin, Zekri, Metz, Maurice, Chebli, Vignes, Tazi: "Deficiency of G3BP1, the stress granules assembly factor, results in abnormal synaptic plasticity and calcium homeostasis in neurons." in: Journal of neurochemistry, (2013) (PubMed).

Kaehler, Isensee, Nonhoff, Terrey, Hucho, Lehrach, Krobitsch: "Ataxin-2-like is a regulator of stress granules and processing bodies." in: PLoS ONE, Vol. 7, Issue 11, pp. e50134, (2012) (PubMed).

Synonyms and alternative names related to G3BP1

G3BP stress granule assembly factor 1 (G3BP1), GTPase activating protein (SH3 domain) binding protein 1 (g3bp1), GTPase activating protein (SH3 domain) binding protein 1 L homeolog (g3bp1.L), Ras-GTPase-activating protein SH3-domain-binding protein (LOC100304885), G3BP stress granule assembly factor 1 (G3bp1), GTPase activating protein (SH3 domain) binding protein 1 (G3bp1), AI849976, B430204O07, C87777, fj17h05, G3BP, g3bp, G3bp, G3BP1, HDH-VIII, MGC53271, mKIAA4115, RGD1310666, wu:fj17h05, zgc:56034

Protein level used designations for G3BP1

  • ATP-dependent DNA helicase VIII
  • G3BP-1
  • GAP SH3 domain-binding protein 1
  • GAP binding protein
  • Ras-GTPase-activating protein SH3-domain-binding protein
  • RasGAP-associated endoribonuclease G3BP
  • ras GTPase-activating protein-binding protein 1
  • GTPase activating protein (SH3 domain) binding protein 1
  • ATP-dependent DNA/RNA helicase G3BP
  • Ras-GTPase-activating protein SH3-domain binding protein 1
  • GAP SH3 binding protein
  • HDH-VIII
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