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GADD34 Products

(Protein Phosphatase 1, Regulatory (Inhibitor) Subunit 15A (PPP1R15A))
This gene is a member of a group of genes whose transcript levels are increased following stressful growth arrest conditions and treatment with DNA-damaging agents. The induction of this gene by ionizing radiation occurs in certain cell lines regardless of p53 status, and its protein response is correlated with apoptosis following ionizing radiation. [provided by RefSeq, Jul 2008].

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Featured GADD34 Categories

GADD34 Antibodies

High quality antibodies with extensive validation data.

GADD34 ELISA Kits

Reliable ELISA kits for a wide range of species.

GADD34 Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended GADD34 Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, ELISA, IHC, FACS, IF
Validations
  • (6)
Cat. No. ABIN184571
Quantity 100 μg
Datasheet Datasheet
Reactivity Dog, Human, Monkey, Mouse, Rat
Application WB, IHC, FACS, IF, IHC (p)
Validations
  • (10)
Cat. No. ABIN1498364
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, IF
Validations
  • (3)
Cat. No. ABIN7269676
Quantity 100 μL
Datasheet Datasheet

Recommended GADD34 ELISA Kits

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Mouse
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6958942
Quantity 96 tests
Datasheet Datasheet
Reactivity Rat
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6958943
Quantity 96 tests
Datasheet Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
Cat. No. ABIN6210738
Quantity 96 tests
Datasheet Datasheet

Recommended GADD34 Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
  • (1)
Cat. No. ABIN7124666
Quantity 50 μg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1315962
Quantity 10 μg
Datasheet Datasheet
Reactivity Rat
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN7418749
Quantity 100 μg
Datasheet Datasheet

Latest Publications for our GADD34 products

Rivera-Reyes, Ye, E Marino, Egolf, E Ciotti, Chor, Liu, Posimo, Park, Pak, Babichev, Sostre-Colón, Tameire, Leli, Koumenis, C Brady, Mancuso, Weber, Gladdy, Qi, Eisinger-Mathason: "YAP1 enhances NF-κB-dependent and independent effects on clock-mediated unfolded protein responses and autophagy in sarcoma." in: Cell death & disease, Vol. 9, Issue 11, pp. 1108, (2018) (PubMed).

Yu, Cui, Zong, Gao, Xu, Gao, Chen, Qin, Guan, Liu, Fu, Li, Wang: "The Orphan Nuclear Receptor NR4A1 Protects Pancreatic β-Cells from Endoplasmic Reticulum (ER) Stress-mediated Apoptosis." in: The Journal of biological chemistry, Vol. 290, Issue 34, pp. 20687-99, (2015) (PubMed).

Zhou, Jeyaraman, Yusoff, Shenolikar: "Phosphorylation at tyrosine 262 promotes GADD34 protein turnover." in: The Journal of biological chemistry, Vol. 288, Issue 46, pp. 33146-55, (2013) (PubMed).

Zhou, Brush, Choy, Shenolikar: "Association with endoplasmic reticulum promotes proteasomal degradation of GADD34 protein." in: The Journal of biological chemistry, Vol. 286, Issue 24, pp. 21687-96, (2011) (PubMed).

Aghi, Rabkin, Martuza: "Effect of chemotherapy-induced DNA repair on oncolytic herpes simplex viral replication." in: Journal of the National Cancer Institute, Vol. 98, Issue 1, pp. 38-50, (2006) (PubMed).

Kojima, Takeuchi, Haneda, Yagi, Hasegawa, Yamaki, Takeda, Akira, Shimokata, Isobe: "The function of GADD34 is a recovery from a shutoff of protein synthesis induced by ER stress: elucidation by GADD34-deficient mice." in: FASEB journal : official publication of the Federation of American Societies for Experimental Biology, Vol. 17, Issue 11, pp. 1573-5, (2003) (PubMed).

Synonyms and alternative names related to GADD34

protein phosphatase 1 regulatory subunit 15A (PPP1R15A), protein phosphatase 1, regulatory (inhibitor) subunit 15A (Ppp1r15a), protein phosphatase 1, regulatory subunit 15A (Ppp1r15a), 9630030H21, Gadd34, GADD34, Myd116, Peg-3, RGD1624209

Protein level used designations for GADD34

  • protein phosphatase 1, regulatory (inhibitor) subunit 15A
  • growth arrest and DNA damage-inducible protein GADD34
  • growth arrest and DNA-damage-inducible 34
  • myeloid differentiation primary response gene 116
  • myeloid differentiation primary response protein MyD116
  • protein phosphatase 1 regulatory subunit 15A
  • myeloid differentiation primary response protein MyD116 homolog
  • progression elevated gene 3 protein
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