GABRB3 Products
(gamma-aminobutyric Acid (GABA) A Receptor, beta 3 (GABRB3))
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This gene encodes a member of the ligand-gated ionic channel family. The encoded protein is one of at least 13 distinct subunits of a multisubunit chloride channel that serves as the receptor for gamma-aminobutyric acid, the major inhibitory transmitter of the nervous system. This gene is located on the long arm of chromosome 15 in a cluster with two genes encoding related subunits of the family. Mutations in this gene may be associated with the pathogenesis of Angelman syndrome, Prader-Willi syndrome, and autism. Alternatively spliced transcript variants encoding distinct isoforms have been described. [provided by RefSeq, Jul 2010].
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Featured GABRB3 Categories
GABRB3 Antibodies
High quality antibodies with extensive validation data.
GABRB3 Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended GABRB3 Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB, IHC, ELISA, IF
Validations
- (4)
Cat. No.
ABIN7153497
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Mouse, Rat
Application
WB, IHC, ICC
Validations
- (1)
- (3)
Cat. No.
ABIN1742465
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Rat
Application
WB
Validations
- (1)
- (1)
Cat. No.
ABIN6254101
Quantity
100 μL
Datasheet
Datasheet
Recommended GABRB3 Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
Cat. No.
ABIN7505216
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
Cat. No.
ABIN7423804
Quantity
100 μg
Datasheet
Datasheet
Latest Publications for our GABRB3 products
: "Distinct mechanisms drive sequential internalization and degradation of GABAARs during global ischemia and reperfusion injury." in: iScience, Vol. 26, Issue 10, pp. 108061, (2023) (PubMed).: "Sex- and age-related changes in GABA signaling components in the human cortex." in: Biology of sex differences, Vol. 10, Issue 1, pp. 5, (2019) (PubMed).
: "GABAA Receptors Are Well Preserved in the Hippocampus of Aged Mice." in: eNeuro, Vol. 6, Issue 4, (2019) (PubMed).
: "Sodium Valproate Ameliorates Neuronal Apoptosis in a Kainic Acid Model of Epilepsy via Enhancing PKC-Dependent GABAAR γ2 Serine 327 Phosphorylation." in: Neurochemical research, Vol. 43, Issue 12, pp. 2343-2352, (2018) (PubMed).
: "Role of spinal GABA receptors in the acute antinociceptive response of mice to hyperbaric oxygen." in: Brain research, Vol. 1699, pp. 107-116, (2018) (PubMed).
: "The Na+/H+ Exchanger Nhe1 Modulates Network Excitability via GABA Release." in: Cerebral cortex (New York, N.Y. : 1991), (2018) (PubMed).
: "Construction of Protein-Based Biosensors Using Ligand-Directed Chemistry for Detecting Analyte Binding." in: Methods in enzymology, Vol. 589, pp. 253-280, (2017) (PubMed).
: "Discovery of allosteric modulators for GABAA receptors by ligand-directed chemistry." in: Nature chemical biology, Vol. 12, Issue 10, pp. 822-30, (2017) (PubMed).
: "Effects of Traumatic Stress Induced in the Juvenile Period on the Expression of Gamma-Aminobutyric Acid Receptor Type A Subunits in Adult Rat Brain." in: Neural plasticity, Vol. 2017, pp. 5715816, (2017) (PubMed).
: "Differential regulation of synaptic and extrasynaptic α4 GABA(A) receptor populations by protein kinase A and protein kinase C in cultured cortical neurons." in: Neuropharmacology, Vol. 105, pp. 124-32, (2016) (PubMed).
Synonyms and alternative names related to GABRB3
gamma-aminobutyric acid type A receptor beta3 subunit (GABRB3), gamma-aminobutyric acid (GABA) A receptor, beta 3 (gabrb3), gamma-aminobutyric acid type A receptor beta 3 subunit (Gabrb3), gamma-aminobutyric acid (GABA) A receptor, subunit beta 3 (Gabrb3), A230092K12Rik, AW049585, beta3, Cp1, eca5, ECA5, Gabrb-3, GABRB3, LOC100230475Protein level used designations for GABRB3
- gamma-aminobutyric acid (GABA) A receptor, beta 3
- gamma-aminobutyric acid receptor subunit beta-3
- gamma-aminobutyric acid A receptor beta 3
- gamma-aminobutyric acid receptor subunit beta-3-like
- GABA-alpha receptor beta-2 subunit
- GABAA receptor beta-3 subunit
- GABA(A) receptor subunit beta-3
- Gamma-aminobutyric acid receptor beta 3
- gamma-aminobutyric acid (GABA-A) receptor, subunit beta 3
- gamma-aminobutyric acid receptor, subunit beta 3
- testis gamma-aminobutyric acid receptor subunit beta 3
- GABA-A receptor beta-3 subunit
- cleft palate 1
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