GABBR2 Products
(gamma-aminobutyric Acid (GABA) B Receptor, 2 (GABBR2))
Categories
The multi-pass membrane protein encoded by this gene belongs to the G-protein coupled receptor 3 family and GABA-B receptor subfamily. The GABA-B receptors inhibit neuronal activity through G protein-coupled second-messenger systems, which regulate the release of neurotransmitters, and the activity of ion channels and adenylyl cyclase. This receptor subunit forms an active heterodimeric complex with GABA-B receptor subunit 1, neither of which is effective on its own. Allelic variants of this gene have been associated with nicotine dependence.[provided by RefSeq, Jan 2010].
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Featured GABBR2 Categories
GABBR2 Antibodies
High quality antibodies with extensive validation data.
GABBR2 ELISA Kits
Reliable ELISA kits for a wide range of species.
GABBR2 Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended GABBR2 Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB, IHC, ELISA, ICC
Validations
- (1)
- (5)
Cat. No.
ABIN1724937
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human, Mouse, Rat
Application
WB, ELISA, IF (cc), IF (p), IHC (p), IHC (fro)
Validations
- (3)
Cat. No.
ABIN674544
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human, Mouse
Application
WB, IHC (p)
Validations
- (3)
Cat. No.
ABIN654172
Quantity
400 μL
Datasheet
Datasheet
Recommended GABBR2 ELISA Kits
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Analytical Method
Validations
Cat. No.
ABIN1134289
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Mouse
Analytical Method
Validations
Cat. No.
ABIN1134290
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Rat
Analytical Method
Validations
Cat. No.
ABIN1134291
Quantity
96 tests
Datasheet
Datasheet
Recommended GABBR2 Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1354633
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
Cat. No.
ABIN1330099
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Mammalian Cells
Validations
Cat. No.
ABIN7538298
Quantity
50 μg
Datasheet
Datasheet
Latest Publications for our GABBR2 products
: "The Role of Spinal GABAB Receptors in Cancer-Induced Bone Pain in Rats." in: The journal of pain : official journal of the American Pain Society, Vol. 18, Issue 8, pp. 933-946, (2018) (PubMed).: "Sex differences in GABABR-GIRK signaling in layer 5/6 pyramidal neurons of the mouse prelimbic cortex." in: Neuropharmacology, Vol. 95, pp. 353-60, (2015) (PubMed).
: "Rapid antidepressants stimulate the decoupling of GABA(B) receptors from GIRK/Kir3 channels through increased protein stability of 14-3-3η." in: Molecular psychiatry, Vol. 20, Issue 3, pp. 298-310, (2015) (PubMed).
: "Novel mechanism of voltage-gated N-type (Cav2.2) calcium channel inhibition revealed through α-conotoxin Vc1.1 activation of the GABA(B) receptor." in: Molecular pharmacology, Vol. 87, Issue 2, pp. 240-50, (2015) (PubMed).
: "Less is More: Design of a Highly Stable Disulfide-Deleted Mutant of Analgesic Cyclic α-Conotoxin Vc1.1." in: Scientific reports, Vol. 5, pp. 13264, (2015) (PubMed).
: "Paraneoplastic Neurological Syndromes and Glutamic Acid Decarboxylase Antibodies." in: JAMA neurology, Vol. 72, Issue 8, pp. 874-81, (2015) (PubMed).
: "Postsynaptic GABAB receptor activity regulates excitatory neuronal architecture and spatial memory." in: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 34, Issue 3, pp. 804-16, (2014) (PubMed).
: "Post-transcriptional regulation of GABAB receptor and GIRK1 channels by Nogo receptor 1." in: Molecular brain, Vol. 6, pp. 30, (2013) (PubMed).
: "Repeated cocaine weakens GABA(B)-Girk signaling in layer 5/6 pyramidal neurons in the prelimbic cortex." in: Neuron, Vol. 80, Issue 1, pp. 159-70, (2013) (PubMed).
: "Defective dentate nucleus GABA receptors in essential tremor." in: Brain : a journal of neurology, Vol. 135, Issue Pt 1, pp. 105-16, (2012) (PubMed).
Synonyms and alternative names related to GABBR2
gamma-aminobutyric acid type B receptor subunit 2 (GABBR2), gamma-aminobutyric acid (GABA) B receptor, 2 (GABBR2), gamma-aminobutyric acid type B receptor subunit 2 (LOC100448699), gamma-aminobutyric acid type B receptor subunit 2 (gabbr2), gamma-aminobutyric acid type B receptor subunit 2 (Gabbr2), gamma-aminobutyric acid (GABA) B receptor, 2 (Gabbr2), gamma-aminobutyric acid (GABA) B receptor, 2 S homeolog (gabbr2.S), gamma-aminobutyric acid (GABA) B receptor, 2 (gabbr2), GABA(B)R2, GABABR2, Gb2, Gm425, Gpr51, GPR51, GPRC3B, HG20, HRIHFB2099, si:dkey-190l1.2Protein level used designations for GABBR2
- gamma-aminobutyric acid (GABA) B receptor, 2
- gamma-aminobutyric acid type B receptor subunit 2-like
- G protein-coupled receptor 51
- G-protein coupled receptor 51
- GABA-B R2 receptor
- GABA-B receptor 2
- GABA-B-R2
- GABA-BR2
- GABABR2
- gamma-aminobutyric acid type B receptor subunit 2
- gb2
- GABA-B receptor, R2 subunit
- gamma-aminobutyric acid B receptor 2
- gamma-aminobutyric acid type B receptor, subunit 2
- ortholog of human G protein-coupled receptor 51 GPR51
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