GABBR1 Products
(gamma-aminobutyric Acid (GABA) B Receptor, 1 (GABBR1))
Categories
Gamma-aminobutyric acid (GABA) is the main inhibitory neurotransmitter in the mammalian central nervous system. GABA exerts its effects through ionotropic [GABA(A/C)] receptors, to produce fast synaptic inhibition, and metabotropic [GABA(B)] receptors, to produce slow, prolonged inhibitory signals. The GABA(B) receptor consists of a heterodimer of two related 7-transmembrane receptors, GABA(B) receptor 1 and GABA(B) receptor 2. The GABA(B) receptor 1 gene is mapped to chromosome 6p21.3 within the HLA class I region close to the HLA-F gene. Susceptibility loci for multiple sclerosis, epilepsy, and schizophrenia have also been mapped in this region. Alternative splicing of this gene generates multiple transcript variants. [provided by RefSeq, Jun 2009].
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Featured GABBR1 Categories
GABBR1 Antibodies
High quality antibodies with extensive validation data.
GABBR1 ELISA Kits
Reliable ELISA kits for a wide range of species.
GABBR1 Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended GABBR1 Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB, ELISA, IF, RNAi
Validations
- (4)
- (6)
Cat. No.
ABIN560976
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human, Mouse, Rat
Application
WB, ELISA, IHC, IF, ICC
Validations
- (4)
Cat. No.
ABIN6261856
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, IF, ICC, IHC (p)
Validations
- (4)
Cat. No.
ABIN2855413
Quantity
100 μL
Datasheet
Datasheet
Recommended GABBR1 ELISA Kits
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6956037
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Human
Analytical Method
Validations
Cat. No.
ABIN1134286
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Mouse
Analytical Method
Validations
Cat. No.
ABIN1134287
Quantity
96 tests
Datasheet
Datasheet
Recommended GABBR1 Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1354631
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1354630
Quantity
25 μg
Datasheet
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
Cat. No.
ABIN1330098
Quantity
10 μg
Datasheet
Datasheet
Latest Publications for our GABBR1 products
: "Oligomerization of the heteromeric γ-aminobutyric acid receptor GABAB in a eukaryotic cell-free system." in: Scientific reports, Vol. 12, Issue 1, pp. 20742, (2022) (PubMed).: "The Role of Spinal GABAB Receptors in Cancer-Induced Bone Pain in Rats." in: The journal of pain : official journal of the American Pain Society, Vol. 18, Issue 8, pp. 933-946, (2018) (PubMed).
: "GABAB receptors couple to Gαq to mediate increases in voltage-dependent calcium current during development." in: Journal of neurochemistry, (2015) (PubMed).
: "Novel mechanism of voltage-gated N-type (Cav2.2) calcium channel inhibition revealed through α-conotoxin Vc1.1 activation of the GABA(B) receptor." in: Molecular pharmacology, Vol. 87, Issue 2, pp. 240-50, (2015) (PubMed).
: "Less is More: Design of a Highly Stable Disulfide-Deleted Mutant of Analgesic Cyclic α-Conotoxin Vc1.1." in: Scientific reports, Vol. 5, pp. 13264, (2015) (PubMed).
: "Paraneoplastic Neurological Syndromes and Glutamic Acid Decarboxylase Antibodies." in: JAMA neurology, Vol. 72, Issue 8, pp. 874-81, (2015) (PubMed).
: "Limbic encephalitis due to GABAB and AMPA receptor antibodies: a case series. ..." in: Journal of neurology, neurosurgery, and psychiatry, (2014) (PubMed).
: "Conjoint occurrence of GABAB receptor antibodies in Lambert-Eaton myasthenic syndrome with antibodies to the voltage gated calcium channel." in: Journal of neuroimmunology, Vol. 273, Issue 1-2, pp. 115-6, (2014) (PubMed).
: "Postsynaptic GABAB receptor activity regulates excitatory neuronal architecture and spatial memory." in: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 34, Issue 3, pp. 804-16, (2014) (PubMed).
: "Cortical stimulation causes long-term changes in H-reflexes and spinal motoneuron GABA receptors." in: Journal of neurophysiology, Vol. 108, Issue 10, pp. 2668-78, (2012) (PubMed).
Synonyms and alternative names related to GABBR1
gamma-aminobutyric acid type B receptor subunit 1 (GABBR1), gamma-aminobutyric acid (GABA) B receptor, 1a (gabbr1a), gamma-aminobutyric acid (GABA) B receptor, 1 (gabbr1), gamma-aminobutyric acid type B receptor subunit 1 (Gabbr1), gamma-aminobutyric acid (GABA) B receptor, 1 (GABBR1), gamma-aminobutyric acid (GABA) B receptor, 1 (Gabbr1), bM573K1.1, dJ271M21.1.1, dJ271M21.1.2, GABA(B)R1, GABAB1, GABABR1, GABAbR1, gabbr1, GABBR1, GABBR1-3, GB1, GPRC3AProtein level used designations for GABBR1
- GABA-BR1
- GABAB, subunit 1c
- gamma-aminobutyric acid type B receptor subunit 1
- seven transmembrane helix receptor
- gamma-aminobutyric acid (GABA) B receptor, 1
- gaba1
- gamma-aminobutyric acid (GABA) B receptor 1
- gamma-aminobutyric acid B receptor 1
- GABA-B receptor 1
- GABA-B-R1
- GABABR1
- gb1
- GABA-BR1b receptor
- bM573K1.1.1 (gamma-aminobutyric acid (GABA) B receptor, 1a)
- gamma-aminobutyric acid (GABA-B) receptor, 1
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