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FZD2 Products

(Frizzled Family Receptor 2 (FZD2))

Categories

This intronless gene is a member of the frizzled gene family. Members of this family encode seven-transmembrane domain proteins that are receptors for the wingless type MMTV integration site family of signaling proteins. This gene encodes a protein that is coupled to the beta-catenin canonical signaling pathway. Competition between the wingless-type MMTV integration site family, member 3A and wingless-type MMTV integration site family, member 5A gene products for binding of this protein is thought to regulate the beta-catenin-dependent and -independent pathways. [provided by RefSeq, Dec 2010].

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Featured FZD2 Categories

FZD2 Antibodies

High quality antibodies with extensive validation data.

FZD2 Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended FZD2 Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, ELISA, IF, IHC
Validations
  • (1)
  • (3)
Cat. No. ABIN302136
Quantity 100 μg
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application WB, ELISA, IF, ICC
Validations
  • (2)
Cat. No. ABIN6258789
Quantity 100 μL
Datasheet Datasheet
Reactivity Cow, Dog, Hamster, Horse, Human, Mouse, Pig, Rat
Application IHC, IHC (p)
Validations
  • (2)
Cat. No. ABIN1048611
Quantity 50 μg
Datasheet Datasheet

Recommended FZD2 ELISA Kits

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Mouse
Analytical Method Quantitative Sandwich ELISA
Validations
Cat. No. ABIN6730675
Quantity 96 tests
Datasheet Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
Cat. No. ABIN6228470
Quantity 96 tests
Datasheet Datasheet

Recommended FZD2 Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Mouse
Source Human Cells
Validations
  • (1)
Cat. No. ABIN7320533
Quantity 50 μg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1354574
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source HEK-293 Cells
Validations
  • (2)
  • (1)
Cat. No. ABIN2181124
Quantity 100 μg
Datasheet Datasheet

Latest Publications for our FZD2 products

Henkel, Tatge, Schöttelndreier, Tao, Dong, Gerhard: "Receptor Binding Domains of TcdB from Clostridioides difficile for Chondroitin Sulfate Proteoglycan-4 and Frizzled Proteins Are Functionally Independent and Additive." in: Toxins, Vol. 12, Issue 12, (2020) (PubMed).

Tao, Zhang, Meraner, Tovaglieri, Wu, Gerhard, Zhang, Stallcup, Miao, He, Hurdle, Breault, Brass, Dong: "Frizzled proteins are colonic epithelial receptors for C. difficile toxin B." in: Nature, Vol. 538, Issue 7625, pp. 350-355, (2017) (PubMed).

Tomizawa, Shinozaki, Motoyoshi, Sugiyama, Yamamoto, Ishige: "Gastric cancer cell proliferation is suppressed by frizzled-2 short hairpin RNA." in: International journal of oncology, Vol. 46, Issue 3, pp. 1018-24, (2015) (PubMed).

Tomizawa, Shinozaki, Motoyoshi, Sugiyama, Yamamoto, Ishige: "Suppression of hepatocellular carcinoma cell proliferation by short hairpin RNA of frizzled 2 with Sonazoid-enhanced irradiation." in: International journal of oncology, Vol. 48, Issue 1, pp. 123-9, (2015) (PubMed).

Hirano, Yonezawa, Yunoue, Habu, Uchida, Yoshioka, Kishida, Kishida, Oyoshi, Fujio, Sugata, Yamahata, Hanaya, Arita: "Immunoreactivity of Wnt5a, Fzd2, Fzd6, and Ryk in glioblastoma: evaluative methodology for DAB chromogenic immunostaining." in: Brain tumor pathology, Vol. 31, Issue 2, pp. 85-93, (2014) (PubMed).

Kaenel, Hahnewald, Wotzkow, Strange, Andres: "Overexpression of EphB4 in the mammary epithelium shifts the differentiation pathway of progenitor cells and promotes branching activity and vascularization." in: Development, growth & differentiation, Vol. 56, Issue 4, pp. 255-75, (2014) (PubMed).

Tomizawa, Shinozaki, Motoyoshi, Sugiyama, Yamamoto, Sueishi: "Short hairpin RNA of frizzled-2 suppresses the proliferation of hepatocellular carcinoma cells." in: Oncology letters, Vol. 8, Issue 4, pp. 1519-1522, (2014) (PubMed).

Tomizawa, Shinozaki, Sugiyama, Yamamoto, Sueishi, Yoshida: "Frizzled-2: A potential novel target for molecular pancreatic cancer therapy." in: Oncology letters, Vol. 7, Issue 1, pp. 74-78, (2013) (PubMed).

Ring, Neth, Weber, Steffens, Faussner et al.: "β-Catenin-dependent pathway activation by both promiscuous "canonical" WNT3a-, and specific "noncanonical" WNT4- and WNT5a-FZD receptor combinations with strong differences in LRP5 and LRP6 ..." in: Cellular signalling, Vol. 26, Issue 2, pp. 260-7, (2013) (PubMed).

Tentler, Nallapareddy, Tan, Spreafico, Pitts, Morelli, Selby, Kachaeva, Flanigan, Kulikowski, Leong, Arcaroli, Messersmith, Eckhardt: "Identification of predictive markers of response to the MEK1/2 inhibitor selumetinib (AZD6244) in K-ras-mutated colorectal cancer." in: Molecular cancer therapeutics, Vol. 9, Issue 12, pp. 3351-62, (2010) (PubMed).

Synonyms and alternative names related to FZD2

frizzled 2 (fz2), frizzled class receptor 2 (fzd2), frizzled class receptor 2 (FZD2), frizzled class receptor 2 (Fzd2), frizzled class receptor 2 S homeolog (fzd2.S), AL033370, AW456835, BG01711, cb383, cFz-2, CG9739, D-Fz2, D-fz2, Dfrz2, dfz(2), DFz-2, DFZ2, DFz2, Dfz2, dFz2, dfz2, dfz2r, Dfz[[2]], Dmel\\CG9739, Dm Fz2, frizzled2, frz2, fz-2, Fz-10, FZ2, Fz2, fz2, fz8, Fz10, FZD2, Fzd10, fzE2, hFz2, Mfz10, Mfz10a, wu:fb70g09, xfz2, zfz2, zg08

Protein level used designations for FZD2

  • CG9739-PA
  • CG9739-PB
  • CG9739-PC
  • CG9739-PD
  • CG9739-PE
  • CG9739-PF
  • CG9739-PG
  • D-frizzled2
  • DFrizzled2
  • Dfrizzled[[2]]
  • Frizzled2
  • drosophila frizzled 2
  • frizzled-2
  • fz2-PA
  • fz2-PB
  • fz2-PC
  • fz2-PD
  • fz2-PE
  • fz2-PF
  • fz2-PG
  • frizzled homolog 8
  • fz-2
  • frizzled homolog 2 (Drosophila)
  • frizzled 2
  • frizzled 2, seven transmembrane spanning receptor
  • frizzled homolog 2
  • Drosophila polarity gene (frizzled) homologue
  • Drosophila polarity gene homolog 2
  • rFz2
  • frizzled-2-like
  • frizzled-10
  • fz-10
  • mFz2
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