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FXYD1 Proteins

(FXYD Domain Containing Ion Transport Regulator 1 (FXYD1))

This gene encodes a member of a family of small membrane proteins that share a 35-amino acid signature sequence domain, beginning with the sequence PFXYD and containing 7 invariant and 6 highly conserved amino acids. The approved human gene nomenclature for the family is FXYD-domain containing ion transport regulator. Mouse FXYD5 has been termed RIC (Related to Ion Channel). FXYD2, also known as the gamma subunit of the Na,K-ATPase, regulates the properties of that enzyme. FXYD1 (phospholemman), FXYD2 (gamma), FXYD3 (MAT-8), FXYD4 (CHIF), and FXYD5 (RIC) have been shown to induce channel activity in experimental expression systems. Transmembrane topology has been established for two family members (FXYD1 and FXYD2), with the N-terminus extracellular and the C-terminus on the cytoplasmic side of the membrane. The protein encoded by this gene is a plasma membrane substrate for several kinases, including protein kinase A, protein kinase C, NIMA kinase, and myotonic dystrophy kinase. It is thought to form an ion channel or regulate ion channel activity. Transcript variants with different 5' UTR sequences have been described in the literature. [provided by RefSeq, Jul 2008].

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FXYD1 Protein (Transcript Variant A) (Myc-DYKDDDDK Tag) (ABIN2728859)

FXYD1 Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD

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FXYD1 Proteins by Origin

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FXYD1 Proteins by Application

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Popular FXYD1 Proteins

Product

Reactivity

Source

Validations

Cat. No.

Quantity

Datasheet

FXYD1 Protein (Transcript Variant A) (Myc-DYKDDDDK Tag)

Reactivity Human

Source HEK-293 Cells

Validations

Cat. No. ABIN2728859

Quantity 20 μg

Datasheet Datasheet

Aliases for FXYD1 Proteins

FXYD domain containing ion transport regulator 1 (FXYD1) Proteins
FXYD domain-containing ion transport regulator 1 (Fxyd1) Proteins
0610012C17Rik Proteins
1110006M24Rik Proteins
PLM Proteins
Plm Proteins
Pml Proteins

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