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FXR2 Products

(Fragile X Mental Retardation, Autosomal Homolog 2 (FXR2))

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The protein encoded by this gene is a RNA binding protein containing two KH domains and one RCG box, which is similar to FMRP and FXR1. It associates with polyribosomes, predominantly with 60S large ribosomal subunits. This encoded protein may self-associate or interact with FMRP and FXR1. It may have a role in the development of fragile X mental retardation syndrome. [provided by RefSeq, Jul 2008].

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Featured FXR2 Categories

FXR2 Antibodies

High quality antibodies with extensive validation data.

FXR2 Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended FXR2 Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human, Mouse
Application WB, IF, ELISA, IHC, ICC
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Cat. No. ABIN6257188
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, IF
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Cat. No. ABIN522996
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application WB, IF
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Cat. No. ABIN1679924
Quantity 100 μg
Datasheet Datasheet

Recommended FXR2 ELISA Kits

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
Cat. No. ABIN6204427
Quantity 96 tests
Datasheet Datasheet

Recommended FXR2 Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Wheat germ
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Cat. No. ABIN1354557
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Tobacco (Nicotiana tabacum)
Validations
Cat. No. ABIN3080466
Quantity 1 mg
Datasheet Datasheet
Reactivity Mouse
Source Tobacco (Nicotiana tabacum)
Validations
Cat. No. ABIN3120180
Quantity 1 mg
Datasheet Datasheet

Latest Publications for our FXR2 products

Darnell, Fraser, Mostovetsky, Darnell: "Discrimination of common and unique RNA-binding activities among Fragile X mental retardation protein paralogs." in: Human molecular genetics, Vol. 18, Issue 17, pp. 3164-77, (2009) (PubMed).

Ewing, Chu, Elisma, Li, Taylor, Climie, McBroom-Cerajewski, Robinson, OConnor, Li, Taylor, Dharsee, Ho, Heilbut, Moore, Zhang, Ornatsky, Bukhman, Ethier, Sheng, Vasilescu, Abu-Farha, Lambert, Duewel et al.: "Large-scale mapping of human protein-protein interactions by mass spectrometry. ..." in: Molecular systems biology, Vol. 3, pp. 89, (2007) (PubMed).

Agulhon, Blanchet, Kobetz, Marchant, Faucon, Sarda, Moraine, Sittler, Biancalana, Malafosse, Abitbol: "Expression of FMR1, FXR1, and FXR2 genes in human prenatal tissues." in: Journal of neuropathology and experimental neurology, Vol. 58, Issue 8, pp. 867-80, (1999) (PubMed).

Tamanini, Bontekoe, Bakker, van Unen, Anar, Willemsen, Yoshida, Galjaard, Oostra, Hoogeveen: "Different targets for the fragile X-related proteins revealed by their distinct nuclear localizations." in: Human molecular genetics, Vol. 8, Issue 5, pp. 863-9, (1999) (PubMed).

Siomi, Zhang, Siomi, Dreyfuss: "Specific sequences in the fragile X syndrome protein FMR1 and the FXR proteins mediate their binding to 60S ribosomal subunits and the interactions among them." in: Molecular and cellular biology, Vol. 16, Issue 7, pp. 3825-32, (1996) (PubMed).

Zhang, OConnor, Siomi, Srinivasan, Dutra, Nussbaum, Dreyfuss: "The fragile X mental retardation syndrome protein interacts with novel homologs FXR1 and FXR2." in: The EMBO journal, Vol. 14, Issue 21, pp. 5358-66, (1996) (PubMed).

Synonyms and alternative names related to FXR2

FMR1 autosomal homolog 2 (FXR2), fragile X mental retardation, autosomal homolog 2 (fxr2), fragile X mental retardation, autosomal homolog 2 (Fxr2), FMR1 autosomal homolog 2 (Fxr2), FMR1L2, Fxr2h, FXR2P, id:ibd5046, zgc:56215, zgc:77472

Protein level used designations for FXR2

  • fragile X mental retardation syndrome-related protein 2
  • fragile X mental retardation syndrome related protein 2
  • fragile X mental retardation, autosomal homolog 2
  • fragile X mental retardation syndrome-related protein 2-like
  • fragile X-mental retardation 1-like 2
  • fragile X mental retardation gene 2, autosomal homolog
  • fragile X mental retardation-related protein 2
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