FTO Products
(Fat Mass and Obesity-Associated (FTO))
Categories
This gene is a nuclear protein of the AlkB related non-haem iron and 2-oxoglutarate-dependent oxygenase superfamily but the exact physiological function of this gene is not known. Other non-heme iron enzymes function to reverse alkylated DNA and RNA damage by oxidative demethylation. Studies in mice and humans indicate a role in nervous and cardiovascular systems and a strong association with body mass index, obesity risk, and type 2 diabetes. [provided by RefSeq, Jul 2011].
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Featured FTO Categories
FTO Antibodies
High quality antibodies with extensive validation data.
FTO ELISA Kits
Reliable ELISA kits for a wide range of species.
FTO Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended FTO Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB, ELISA, IHC, IF
Validations
- (4)
Cat. No.
ABIN7127502
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, IHC (p), FACS
Validations
- (3)
Cat. No.
ABIN390964
Quantity
400 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, ELISA, IHC, IP
Validations
- (3)
Cat. No.
ABIN1169073
Quantity
100 μg
Datasheet
Datasheet
Recommended FTO ELISA Kits
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6966656
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Rat
Analytical Method
Quantitative Sandwich ELISA
Validations
Cat. No.
ABIN5594574
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Mouse
Analytical Method
Quantitative Sandwich ELISA
Validations
Cat. No.
ABIN6228458
Quantity
96 tests
Datasheet
Datasheet
Recommended FTO Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1354483
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Mouse
Source
Escherichia coli (E. coli)
Validations
Cat. No.
ABIN1344345
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
Cat. No.
ABIN1344349
Quantity
10 μg
Datasheet
Datasheet
Latest Publications for our FTO products
: "m6A in mRNA coding regions promotes translation via the RNA helicase-containing YTHDC2." in: Nature communications, Vol. 10, Issue 1, pp. 5332, (2020) (PubMed).: "Programmable RNA N6-methyladenosine editing by CRISPR-Cas9 conjugates." in: Nature chemical biology, Vol. 15, Issue 9, pp. 865-871, (2019) (PubMed).
: "N6-Methyladenosine Guides mRNA Alternative Translation during Integrated Stress Response." in: Molecular cell, Vol. 69, Issue 4, pp. 636-647.e7, (2019) (PubMed).
: "N6-methyladenosine RNA modification regulates embryonic neural stem cell self-renewal through histone modifications." in: Nature neuroscience, Vol. 21, Issue 2, pp. 195-206, (2019) (PubMed).
: "Dynamic m6A modification regulates local translation of mRNA in axons." in: Nucleic acids research, Vol. 46, Issue 3, pp. 1412-1423, (2019) (PubMed).
: "The Role of The RNA Demethylase FTO (Fat Mass and Obesity-Associated) and mRNA Methylation in Hippocampal Memory Formation." in: Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, Vol. 42, Issue 7, pp. 1502-1510, (2017) (PubMed).
: "FTO modulates circadian rhythms and inhibits the CLOCK-BMAL1-induced transcription." in: Biochemical and biophysical research communications, Vol. 464, Issue 3, pp. 826-32, (2015) (PubMed).
: "N6-adenosine methylation in MiRNAs." in: PLoS ONE, Vol. 10, Issue 2, pp. e0118438, (2015) (PubMed).
: "Dynamic m(6)A mRNA methylation directs translational control of heat shock response." in: Nature, Vol. 526, Issue 7574, pp. 591-4, (2015) (PubMed).
: "The obesity-associated FTO gene encodes a 2-oxoglutarate-dependent nucleic acid demethylase. ..." in: Science (New York, N.Y.), Vol. 318, Issue 5855, pp. 1469-72, (2007) (PubMed).
Synonyms and alternative names related to FTO
FTO, alpha-ketoglutarate dependent dioxygenase (FTO), fat mass and obesity associated (Fto), FTO, alpha-ketoglutarate dependent dioxygenase (Fto), fat mass and obesity associated L homeolog (fto.L), AW743446, mKIAA1752, RGD1305121Protein level used designations for FTO
- alpha-ketoglutarate-dependent dioxygenase FTO
- fat mass and obesity-associated protein
- protein fto
- protein fatso
- fat mass and obesity associated protein
- Protein fatso
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