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FTH1 Products

(Ferritin, Heavy Polypeptide 1 (FTH1))

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This gene encodes the heavy subunit of ferritin, the major intracellular iron storage protein in prokaryotes and eukaryotes. It is composed of 24 subunits of the heavy and light ferritin chains. Variation in ferritin subunit composition may affect the rates of iron uptake and release in different tissues. A major function of ferritin is the storage of iron in a soluble and nontoxic state. Defects in ferritin proteins are associated with several neurodegenerative diseases. This gene has multiple pseudogenes. Several alternatively spliced transcript variants have been observed, but their biological validity has not been determined. [provided by RefSeq, Jul 2008].

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Featured FTH1 Categories

FTH1 Antibodies

High quality antibodies with extensive validation data.

FTH1 ELISA Kits

Reliable ELISA kits for a wide range of species.

FTH1 Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended FTH1 Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, IHC, IP, ICC
Validations
  • (8)
Cat. No. ABIN7435313
Quantity 100 μL
Datasheet Datasheet
Reactivity Rat
Application WB, IHC, IP, ICC
Validations
  • (9)
Cat. No. ABIN7437164
Quantity 100 μL
Datasheet Datasheet
Reactivity Pig
Application WB, IHC, IP, ICC
Validations
  • (7)
Cat. No. ABIN7440041
Quantity 100 μL
Datasheet Datasheet

Recommended FTH1 ELISA Kits

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (5)
  • (1)
Cat. No. ABIN6955747
Quantity 96 tests
Datasheet Datasheet
Reactivity Rat
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
  • (1)
Cat. No. ABIN6955749
Quantity 96 tests
Datasheet Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6966709
Quantity 96 tests
Datasheet Datasheet

Recommended FTH1 Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1354475
Quantity 10 μg
Datasheet Datasheet
Reactivity
Source Escherichia coli (E. coli)
Validations
  • (3)
  • (1)
Cat. No. ABIN1095588
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN7505081
Quantity 100 μg
Datasheet Datasheet

Latest Publications for our FTH1 products

Inokura, Fujiwara, Saito, Iino, Hatta, Okitsu, Fukuhara, Onishi, Ishizawa, Shimoda, Harigae: "Impact of TET2 deficiency on iron metabolism in erythroblasts." in: Experimental hematology, Vol. 49, pp. 56-67.e5, (2017) (PubMed).

Yang, Gong, Yang, Zhang, Wang, Su, Wen, Zhang: "MR molecular imaging of tumours using ferritin heavy chain reporter gene expression mediated by the hTERT promoter." in: European radiology, Vol. 26, Issue 11, pp. 4089-4097, (2016) (PubMed).

Zhang, Zhao, Chang, Zhang, Chu, Zhang, Liu, Guo, Wang, Gao, Zhang, Chu: "Calcium channel blockers ameliorate iron overload-associated hepatic fibrosis by altering iron transport and stellate cell apoptosis." in: Toxicology and applied pharmacology, Vol. 301, pp. 50-60, (2016) (PubMed).

Banerjee, Sahoo, Anand, Bir, Chakrabarti: "The Oral Iron Chelator, Deferasirox, Reverses the Age-Dependent Alterations in Iron and Amyloid-β Homeostasis in Rat Brain: Implications in the Therapy of Alzheimer's Disease." in: Journal of Alzheimer's disease : JAD, Vol. 49, Issue 3, pp. 681-93, (2015) (PubMed).

Mumby, Ramakrishnan, Evans, Griffiths, Quinlan: "Methemoglobin-induced signaling and chemokine responses in human alveolar epithelial cells." in: American journal of physiology. Lung cellular and molecular physiology, Vol. 306, Issue 1, pp. L88-100, (2014) (PubMed).

Ciregia, Giusti, Molinaro, Niccolai, Agretti, Rago, Di Coscio, Vitti, Basolo, Iacconi, Tonacchera, Lucacchini: "Presence in the pre-surgical fine-needle aspiration of potential thyroid biomarkers previously identified in the post-surgical one." in: PLoS ONE, Vol. 8, Issue 9, pp. e72911, (2013) (PubMed).

Ge, Xu, Feng, Wang, Li, Feng: "Relationships among serum C-reactive protein, receptor for advanced glycation products, metabolic dysfunction, and cognitive impairments." in: BMC neurology, Vol. 13, pp. 110, (2013) (PubMed).

Potrykus, Stead, Maccallum, Urgast, Raab, van Rooijen, Feldmann, Brown: "Fungal iron availability during deep seated candidiasis is defined by a complex interplay involving systemic and local events." in: PLoS pathogens, Vol. 9, Issue 10, pp. e1003676, (2013) (PubMed).

Kim, Moore, Fussenegger: "Genetically programmed superparamagnetic behavior of mammalian cells." in: Journal of biotechnology, Vol. 162, Issue 2-3, pp. 237-45, (2012) (PubMed).

Sammarco, Ditch, Banerjee, Grabczyk: "Ferritin L and H subunits are differentially regulated on a post-transcriptional level." in: The Journal of biological chemistry, Vol. 283, Issue 8, pp. 4578-87, (2008) (PubMed).

Synonyms and alternative names related to FTH1

ferritin heavy chain 1 (FTH1), ferritin, heavy polypeptide 1 L homeolog (fth1.L), ferritin, heavy polypeptide 1 S homeolog (fth1.S), ferritin heavy polypeptide 1 (Fth1), ferritin heavy chain 1 (Fth1), ferritin, heavy polypeptide 1a (fth1a), ferritin (EAMY_RS19690), ferritin, heavy polypeptide 1 (fth1), tudor domain containing 9 (TDRD9), ferritin, heavy polypeptide 1 (FTH1), ferritin, heavy polypeptide 1 a (fth1a), apoferritin, fb06g09, ferritin, FHC, fhc, FTH, fth, Fth, fth1, fth1b, FTHL6, fthl6, ftn-2, HFt, hm:zeh1145, MFH, PIG15, pig15, PLIF, plif, wu:fb06g09, wu:fq18c10, zeh1145

Protein level used designations for FTH1

  • apoferritin
  • cell proliferation-inducing gene 15 protein
  • ferritin H subunit
  • ferritin heavy chain
  • placenta immunoregulatory factor
  • proliferation-inducing protein 15
  • ferritin H chain
  • XL2-17
  • ferritin H subunit A
  • ferritin heavy chain 2
  • ferritin heavy chain A
  • ferritin H subunit B
  • ferritin heavy chain 1
  • ferritin heavy chain B
  • ferritin, heavy polypeptide 1 b
  • ferritin heavy polypeptide 1
  • ferritin heavy-chain
  • H-ferritin
  • Ferritin subunit H
  • ferritin, heavy polypeptide 1
  • tudor domain containing 9
  • Ferritin H subunit
  • ferritin heavy chain 1 a
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