FRS2 Products
(Fibroblast Growth Factor Receptor Substrate 2 (FRS2))
Categories
Adapter protein that links activated FGR and NGF receptors to downstream signaling pathways. Plays an important role in the activation of MAP kinases and in the phosphorylation of PIK3R1, the regulatory subunit of phosphatidylinositol 3- kinase, in response to ligand-mediated activation of FGFR1. Modulates signaling via SHC1 by competing for a common binding site on NTRK1.
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Featured FRS2 Categories
FRS2 Antibodies
High quality antibodies with extensive validation data.
FRS2 ELISA Kits
Reliable ELISA kits for a wide range of species.
FRS2 Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended FRS2 Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human, Mouse
Application
WB, ELISA
Validations
- (3)
Cat. No.
ABIN3184696
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, IHC, IP, ICC
Validations
- (2)
Cat. No.
ABIN7439384
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, ELISA
Validations
- (2)
Cat. No.
ABIN7180012
Quantity
100 μL
Datasheet
Datasheet
Recommended FRS2 ELISA Kits
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Mouse
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6966796
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6966795
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Human, Mouse
Analytical Method
Qualitative Cell ELISA
Validations
Cat. No.
ABIN1380814
Quantity
2 x 96 tests
Datasheet
Datasheet
Recommended FRS2 Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (2)
- (1)
Cat. No.
ABIN1354441
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
- (1)
Cat. No.
ABIN7122957
Quantity
50 μg
Datasheet
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1354439
Quantity
10 μg
Datasheet
Datasheet
Latest Publications for our FRS2 products
: "Targeting extracellular and juxtamembrane FGFR2 mutations in chemotherapy-refractory cholangiocarcinoma." in: NPJ precision oncology, Vol. 5, Issue 1, pp. 80, (2021) (PubMed).: "Inorganic polyphosphates stimulate FGF23 expression through the FGFR pathway." in: Biochemical and biophysical research communications, Vol. 428, Issue 2, pp. 298-302, (2012) (PubMed).
: "STAT1 and STAT3 do not participate in FGF-mediated growth arrest in chondrocytes." in: Journal of cell science, Vol. 121, Issue Pt 3, pp. 272-81, (2008) (PubMed).
: "Bisindolylmaleimide I suppresses fibroblast growth factor-mediated activation of Erk MAP kinase in chondrocytes by preventing Shp2 association with the Frs2 and Gab1 adaptor proteins." in: The Journal of biological chemistry, Vol. 282, Issue 5, pp. 2929-36, (2007) (PubMed).
Synonyms and alternative names related to FRS2
fibroblast growth factor receptor substrate 2 (FRS2), fibroblast growth factor receptor substrate 2b (frs2b), fibroblast growth factor receptor substrate 2 (Frs2), 4732458E18, C330018A15Rik, frs2, FRS2A, FRS2alpha, Frs2alpha, SNT, SNT-1, SNT1, wu:fd21h10, zgc:91973Protein level used designations for FRS2
- fibroblast growth factor receptor substrate 2
- FGFR signalling adaptor
- FGFR substrate 2
- FGFR-signaling adaptor SNT
- suc1-associated neurotrophic factor target 1
- FRS2-alpha
- SNT-1
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