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(Folylpolyglutamate Synthase (FPGS))
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This gene encodes the folylpolyglutamate synthetase enzyme. This enzyme has a central role in establishing and maintaining both cytosolic and mitochondrial folylpolyglutamate concentrations and, therefore, is essential for folate homeostasis and the survival of proliferating cells. This enzyme catalyzes the ATP-dependent addition of glutamate moieties to folate and folate derivatives. While several transcript variants may exist for this gene, the full-length natures of only two have been biologically validated to date. These two variants encode distinct isoforms. [provided by RefSeq, Jul 2008].
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FPGS Antibodies
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FPGS Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended FPGS Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Mouse
Application
WB, IHC, IP, ICC
Validations
- (4)
Cat. No.
ABIN7444802
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, IHC (p), FACS
Validations
- (4)
Cat. No.
ABIN390963
Quantity
400 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, ELISA
Validations
- (1)
Cat. No.
ABIN7153018
Quantity
100 μg
Datasheet
Datasheet
Recommended FPGS ELISA Kits
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6966873
Quantity
96 tests
Datasheet
Datasheet
Recommended FPGS Proteins
Latest Publications for our FPGS products
: "A folylpoly-γ-glutamate synthase single nucleotide polymorphism associated with response to pemetrexed treatment combined with platinum for non-small cell lung cancer." in: Lung cancer (Amsterdam, Netherlands), Vol. 102, pp. 15-20, (2016) (PubMed).Synonyms and alternative names related to FPGS
folylpolyglutamate synthase (fpgs), folylpolyglutamate synthase (fpgS), folylpolyglutamate synthase (FPGS), folylpolyglutamate synthase (SCO2614), folylpolyglutamate synthase (fgs), folylpolyglutamate synthase (folC), dihydrofolate synthase (folC), folylpolyglutamate synthase, mitochondrial (CpipJ_CPIJ008043), folylpolyglutamate synthase (Fpgs), folylpolyglutamyl synthetase (Fpgs), AA408187, BA4689, FPGS, fpgS, SCC88.25c, wu:fk49h03, wu:fk51d09, zgc:63807Protein level used designations for FPGS
- fk51d09
- folylpolyglutamate synthase, mitochondrial
- folylpolyglutamate synthase
- folylpoly-gamma-glutamate synthetase
- tetrahydrofolate synthase
- tetrahydrofolylpolyglutamate synthase
- Folylpoly-gamma-glutamate synthetase
- Tetrahydrofolate synthase
- Tetrahydrofolylpolyglutamate synthase
- folylpoly-gammaglutamate synthetase
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