FOXO Antibodies
(Forkhead Box, Sub-Group O (FOXO))
Transcription factor involved in the regulation of the insulin signaling pathway. Consistently activates both the downstream target Thor\d4EBP and the feedback control target InR. Involved in negative regulation of the cell cycle, modulating cell growth and proliferation. In response to cellular stresses, such as nutrient deprivation or increased levels of reactive oxygen species, foxo is activated and inhibits growth through the action of target genes such as Thor. Foxo activated in the adult fat body can regulate lifespan in adults\; an insulin peptide itself may function as one secondary messenger of insulin-regulated aging. Also regulates Lip4, homolog of human acid lipases, thereby acting as a key modulator of lipid metabolism by insulin signaling and integrates insulin responses to glucose and lipid homeostasis.
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Featured FOXO Categories
FOXO Antibodies
High quality antibodies with extensive validation data.
Recommended FOXO Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Drosophila melanogaster
Application
ELISA, WB
Validations
Cat. No.
ABIN780412
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Drosophila melanogaster
Application
ELISA, WB
Validations
Cat. No.
ABIN4889143
Quantity
100 μg
Datasheet
Datasheet
Synonyms and alternative names related to FOXO
forkhead box, sub-group O (foxo), 3143, Afx, anon-WO0118547.374, CG3143, cg3143, Dfoxo, dFOXO, dFoxO, dFoxo, dfoxo, Dmel\\CG3143, DmQ95V5, fd88A, FKHR, FOXO, FoxO, Foxo, foxO, foxo, Q95V55Protein level used designations for FOXO
- CG3143-PB
- CG3143-PC
- CG3143-PF
- CG3143-PG
- forkhead Box O
- forkhead bOX-containing protein, subfamily O
- forkhead box
- forkhead box sub-group O
- forkhead box type O
- forkhead box, subgroup O
- forkhead transcription factor
- foxo-PB
- foxo-PC
- foxo-PF
- foxo-PG
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